Patents Assigned to DFB Soria, LLC
  • Topical therapy for the treatment of skin malignancies using nanoparticles of taxanes
    Patent number: 11633349
    Abstract: Disclosed are methods useful for the topical therapeutic treatment of skin malignancies including skin cancers and cutaneous metastases using compositions containing nanoparticles of paclitaxel or other taxanes.
    Type: Grant
    Filed: November 1, 2021
    Date of Patent: April 25, 2023
    Assignee: DFB SORIA, LLC
    Inventor: Gere Dizerega
  • Delivery of drug nanoparticles and methods of use thereof
    Patent number: 11331278
    Abstract: A hydrophobic topical skin composition is disclosed. The composition includes greater than 50% w/w of the composition of a continuous hydrophobic carrier, 5-24% w/w of one or more volatile silicone fluids, and 0.1 to 5% w/w of the composition of a plurality of taxane nanoparticles, wherein the mean particle size (number) of the taxane nanoparticles is from 0.1 microns to 1.5 microns, and wherein the taxane nanoparticles are crystalline nanoparticles or a combination of amorphous and crystalline nanoparticles.
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: May 17, 2022
    Assignee: DFB SORIA, LLC
    Inventors: Keith Johnson, Robert Lathrop, Meidong Yang, Holly Maulhardt, Roland Franke
  • TOPICAL THERAPY FOR THE TREATMENT OF SKIN MALIGNANCIES USING NANOPARTICLES OF TAXANES
    Publication number: 20220117882
    Abstract: Disclosed are methods useful for the topical therapeutic treatment of skin malignancies including skin cancers and cutaneous metastases using compositions containing nanoparticles of paclitaxel or other taxanes.
    Type: Application
    Filed: November 1, 2021
    Publication date: April 21, 2022
    Applicant: DFB SORIA, LLC
    Inventor: Gere DIZEREGA
  • Topical therapy for the treatment of skin malignancies using nanoparticles of taxanes
    Patent number: 11191717
    Abstract: Disclosed are methods useful for the topical therapeutic treatment of skin malignancies including skin cancers and cutaneous metastases using compositions containing nanoparticles of paclitaxel or other taxanes.
    Type: Grant
    Filed: September 22, 2020
    Date of Patent: December 7, 2021
    Assignee: DFB SORIA, LLC
    Inventor: Gere Dizerega
  • DELIVERY OF DRUG NANOPARTICLES AND METHODS OF USE THEREOF
    Publication number: 20210106539
    Abstract: A hydrophobic topical skin composition is disclosed. The composition includes greater than 50% w/w of the composition of a continuous hydrophobic carrier, 5-24% w/w of one or more volatile silicone fluids, and 0.1 to 5% w/w of the composition of a plurality of taxane nanoparticles, wherein the mean particle size (number) of the taxane nanoparticles is from 0.1 microns to 1.5 microns, and wherein the taxane nanoparticles are crystalline nanoparticles or a combination of amorphous and crystalline nanoparticles.
    Type: Application
    Filed: December 4, 2020
    Publication date: April 15, 2021
    Applicant: DFB Soria, LLC
    Inventors: Keith JOHNSON, Robert LATHROP, Meidong YANG, Holly MAULHARDT, Roland FRANKE
  • TOPICAL THERAPY FOR THE TREATMENT OF SKIN MALIGNANCIES USING NANOPARTICLES OF TAXANES
    Publication number: 20210069099
    Abstract: Disclosed are methods useful for the topical therapeutic treatment of skin malignancies including skin cancers and cutaneous metastases using compositions containing nanoparticles of paclitaxel or other taxanes.
    Type: Application
    Filed: September 22, 2020
    Publication date: March 11, 2021
    Applicant: DFB SORIA, LLC
    Inventor: Gere DIZEREGA
  • Delivery of drug nanoparticles and methods of use thereof
    Patent number: 10918606
    Abstract: Disclosed are compositions and methods useful for enhancing the skin penetration of drug nanoparticles. The compositions can be hydrophobic and include a hydrophobic carrier, a volatile silicone fluid, and drug nanoparticles. Also disclosed are methods for inhibiting crystal growth of drug nanoparticles in an aqueous carrier or a hydrophobic carrier. Further, methods to topically treat psoriasis using compositions containing nanoparticles of paclitaxel or other taxanes are disclosed.
    Type: Grant
    Filed: September 11, 2019
    Date of Patent: February 16, 2021
    Assignee: DFB Soria, LLC
    Inventors: Keith Johnson, Robert Lathrop, Meidong Yang, Holly Maulhardt, Roland Franke
  • Topical therapy for the treatment of skin malignancies using nanoparticles of taxanes
    Patent number: 10842736
    Abstract: Disclosed are methods useful for the topical therapeutic treatment of skin malignancies including skin cancers and cutaneous metastases using compositions containing nanoparticles of paclitaxel or other taxanes.
    Type: Grant
    Filed: December 6, 2019
    Date of Patent: November 24, 2020
    Assignee: DFB Soria, LLC
    Inventor: Gere Dizerega
  • TOPICAL THERAPY FOR THE TREATMENT OF SKIN MALIGNANCIES USING NANOPARTICLES OF TAXANES
    Publication number: 20200188295
    Abstract: Disclosed are methods useful for the topical therapeutic treatment of skin malignancies including skin cancers and cutaneous metastases using compositions containing nanoparticles of paclitaxel or other taxanes.
    Type: Application
    Filed: December 6, 2019
    Publication date: June 18, 2020
    Applicant: DFB SORIA, LLC
    Inventor: Gere DIZEREGA
  • DELIVERY OF DRUG NANOPARTICLES AND METHODS OF USE THEREOF
    Publication number: 20200069600
    Abstract: Disclosed are compositions and methods useful for enhancing the skin penetration of drug nanoparticles. The compositions can be hydrophobic and include a hydrophobic carrier, a volatile silicone fluid, and drug nanoparticles. Also disclosed are methods for inhibiting crystal growth of drug nanoparticles in an aqueous carrier or a hydrophobic carrier. Further, methods to topically treat psoriasis using compositions containing nanoparticles of paclitaxel or other taxanes are disclosed.
    Type: Application
    Filed: September 11, 2019
    Publication date: March 5, 2020
    Applicant: DFB Soria, LLC
    Inventors: Keith JOHNSON, Robert LATHROP, Meidong YANG, Holly MAULHARDT, Roland FRANKE
  • Topical therapy for the treatment of skin malignancies using nanoparticles of taxanes
    Patent number: 10555898
    Abstract: Disclosed are methods useful for the topical therapeutic treatment of skin malignancies including skin cancers and cutaneous metastases using compositions containing nanoparticles of paclitaxel or other taxanes.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: February 11, 2020
    Assignee: DFB SORIA, LLC
    Inventor: Gere Dizerega
  • Delivery of drug nanoparticles and methods of use thereof
    Patent number: 10449162
    Abstract: Disclosed are compositions and methods useful for enhancing the skin penetration of drug nanoparticles. The compositions can be hydrophobic and include a hydrophobic carrier, a volatile silicone fluid, and drug nanoparticles. Also disclosed are methods for inhibiting crystal growth of drug nanoparticles in an aqueous carrier or a hydrophobic carrier. Further, methods to topically treat psoriasis using compositions containing nanoparticles of paclitaxel or other taxanes are disclosed.
    Type: Grant
    Filed: February 19, 2018
    Date of Patent: October 22, 2019
    Assignee: DFB Soria LLC
    Inventors: Keith Johnson, Robert Lathrop, Meidong Yang, Holly Maulhardt, Roland Franke
  • TOPICAL THERAPY FOR THE TREATMENT OF SKIN KERATOSES USING NANOPARTICLES OF TAXANES
    Publication number: 20190216767
    Abstract: Disclosed are methods useful for the topical therapeutic treatment of skin keratoses including precancerous skin keratoses such as actinic keratosis using compositions containing nanoparticles of paclitaxel or other taxanes.
    Type: Application
    Filed: February 21, 2019
    Publication date: July 18, 2019
    Applicant: DFB SORIA, LLC
    Inventor: Gere DIZEREGA
  • TOPICAL THERAPY FOR THE TREATMENT OF SKIN MALIGNANCIES USING NANOPARTICLES OF TAXANES
    Publication number: 20190183787
    Abstract: Disclosed are methods useful for the topical therapeutic treatment of skin malignancies including skin cancers and cutaneous metastases using compositions containing nanoparticles of paclitaxel or other taxanes.
    Type: Application
    Filed: February 21, 2019
    Publication date: June 20, 2019
    Applicant: DFB SORIA, LLC
    Inventor: Gere DIZEREGA
  • DELIVERY OF DRUG NANOPARTICLES AND METHODS OF USE THEREOF
    Publication number: 20180177739
    Abstract: Disclosed are compositions and methods useful for enhancing the skin penetration of drug nanoparticles. The compositions can be hydrophobic and include a hydrophobic carrier, a volatile silicone fluid, and drug nanoparticles. Also disclosed are methods for inhibiting crystal growth of drug nanoparticles in an aqueous carrier or a hydrophobic carrier. Further, methods to topically treat psoriasis using compositions containing nanoparticles of paclitaxel or other taxanes are disclosed.
    Type: Application
    Filed: February 19, 2018
    Publication date: June 28, 2018
    Applicant: DFB Soria, LLC
    Inventors: Keith JOHNSON, Robert LATHROP, Meidong YANG, Holly MAULHARDT, Roland FRANKE