Patents Assigned to DFH THERAPEUTICS
  • Triterpene amine derivatives
    Patent number: 11236122
    Abstract: The present invention concerns novel pharmaceutically active triterpene amine derivatives, pharmaceutical compositions containing the same, their use as medicaments, and the use of the compounds for the manufacture of specific medicaments. The present invention also concerns a method of treatment involving administration of the triterpene amine compounds. Specifically, the compounds are derivatives of betulinic acid having substitutions at one or more of the C-3, C-28 and C-19 positions as further described herein. The novel compounds are useful as antiretroviral agents. In particular, the novel compounds are useful for the treatment of Human Immunodeficiency Virus-1 (HIV-1).
    Type: Grant
    Filed: June 28, 2019
    Date of Patent: February 1, 2022
    Assignees: DFH THERAPEUTICS, The United States Of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Theodore J. Nitz, Carl T. Wild, David E. Martin, Eric O. Freed
  • C-3 novel triterpenone with C-17 reverse amide derivatives as HIV inhibitors
    Patent number: 10533035
    Abstract: The invention relates to C-3 novel triterpenone with C-17 reverse amide derivatives, related compounds, and pharmaceutical compositions useful for the therapeutic treatment of viral diseases and particularly HIV mediated diseases.
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: January 14, 2020
    Assignees: HETERO LABS LTD., DFH THERAPEUTICS, INC.
    Inventors: Bandi Parthasaradhi Reddy, Gazula Levi David Krupadanam, Adulla Panduranga Reddy, Kasireddy Bhaskar Reddy, Lanka Vl Subrahmanyam, Kura Rathnakar Reddy