Abstract: Systems, devices, and methods are provided for an improved mass spectrometry detection system for pulse counting applications. The detector can comprise an electron multiplier and circuitry, such as a transimpedance amplifier, that allows for the gain of the detector to be decreased, which in turn leads to a pulse counting detector with a high dynamic range. In some embodiments, the detector can operate at count rates of up to about 20 million counts per second without reaching saturation. Further, the lifetime of the detector can be extended. A variety of embodiments of systems, devices, and methods in conjunction with the disclosures are provided.