Abstract: The present invention relates to a composition comprising a peptide of the formula: (Xaa)n1-Xaa1-His-Thr-Asp-(Xaa)n2 wherein Xaa is any amino acid; Xaa1 is a hydrophobic amino acid; n1 is 0-10; and n2 is 0-10; and derivatives thereof; and insulin. Complexes of insulin and the peptides, methods of dispersing multimeric insulin complexes and methods of regulating in vivo blood glucose levels, particularly in the treatment of diabetes are also described.
Type:
Application
Filed:
November 22, 2006
Publication date:
August 27, 2009
Applicant:
DIA-B TECH LIMITED
Inventors:
Mark A. Myers, Robyn Gray, Sarah Paule, Paul Zev Zimmet