Abstract: Provided herein are compositions, kits, methods and devices for cyanide detection, particularly for cyanide detection in biological samples such as whole blood. The method comprises (1) contacting a sample with a cobinamide conjugate comprising a cobinamide moiety and a carrier; and (2) measuring the absorbance of light by the cobinamide conjugate. The present disclosure provides field-deployable cyanide detection methods, compositions, kits and devices, which provide rapid, accurate readout at the point of contact. Further provided herein is a method for determining exposure of a subject to cyanide.
Type:
Grant
Filed:
July 7, 2015
Date of Patent:
January 17, 2017
Assignee:
DIAGNOSTIC CONSULTING NETWORK, INC.
Inventors:
Brendan O'Farrell, Hans Boehringer, Roy Chung, Winnie Tong
Abstract: Provided herein are compositions, kits, methods and devices for cyanide detection, particularly for cyanide detection in biological samples such as whole blood. The method comprises (1) contacting a sample with a cobinamide conjugate comprising a cobinamide moiety and a carrier; and (2) measuring the absorbance of light by the cobinamide conjugate. The present disclosure provides field-deployable cyanide detection methods, compositions, kits and devices, which provide rapid, accurate readout at the point of contact. Further provided herein is a method for determining exposure of a subject to cyanide.
Type:
Application
Filed:
July 7, 2015
Publication date:
October 29, 2015
Applicant:
DIAGNOSTIC CONSULTING NETWORK, INC.
Inventors:
Brendan O'FARRELL, Hans BOEHRINGER, Roy CHUNG, Winnie TONG
Abstract: Provided herein are compositions, kits, methods and devices for cyanide detection, particularly for cyanide detection in biological samples such as whole blood. The method comprises (1) contacting a sample with a cobinamide conjugate comprising a cobinamide moiety and a carrier; and (2) measuring the absorbance of light by the cobinamide conjugate. The present disclosure provides field-deployable cyanide detection methods, compositions, kits and devices, which provide rapid, accurate readout at the point of contact. Further provided herein is a method for determining exposure of a subject to cyanide.
Type:
Grant
Filed:
March 14, 2013
Date of Patent:
August 18, 2015
Assignee:
Diagnostic Consulting Network, Inc.
Inventors:
Brendan O'Farrell, Hans Boehringer, Roy Chung, Winnie Tong
Abstract: Provided herein are compositions, kits, methods and devices for cyanide detection, particularly for cyanide detection in biological samples such as whole blood. The method comprises (1) contacting a sample with a cobinamide conjugate comprising a cobinamide moiety and a carrier; and (2) measuring the absorbance of light by the cobinamide conjugate. The present disclosure provides field-deployable cyanide detection methods, compositions, kits and devices, which provide rapid, accurate readout at the point of contact. Further provided herein is a method for determining exposure of a subject to cyanide.
Type:
Application
Filed:
March 14, 2013
Publication date:
December 26, 2013
Applicant:
Diagnostic Consulting Network, Inc.
Inventors:
Brendan O'FARRELL, Hans BOEHRINGER, Roy CHUNG, Winnie TONG