Patents Assigned to Diagnostics Hybrids, Inc.
  • Systems for detection and production of respiratory, herpes and enteric viruses
    Patent number: 7435588
    Abstract: The present invention generally relates to the field of diagnostic microbiology, and, more particularly, to compositions and methods for detecting and differentiating one or more viruses or other intracellular parasites present in a specimen. The present invention also provides compositions and methods to evaluate the susceptibility of organisms to antimicrobial agents.
    Type: Grant
    Filed: April 28, 2006
    Date of Patent: October 14, 2008
    Assignee: Diagnostic Hybrids, Inc.
    Inventors: Yung T. Huang, Joseph A. Jollick, Jr.
  • In situ growth, freezing and testing of cultured cells
    Patent number: 7341829
    Abstract: The present invention provides methods and compositions for the in situ growth, freezing and testing of cultured cells. In particular, the present invention provides methods and compositions for the long-term preservation of cells in ready-to-use formats for testing. In addition, the present invention provides rapid and easy to use means to diagnose viral and other infections. Furthermore, the present invention provides easy to use means to grow and store cells in situ for testing methods. Indeed, the present invention makes viral, chlamydial and other diagnostic methods accessible to small laboratories, including those without cell culture capabilities.
    Type: Grant
    Filed: September 9, 2002
    Date of Patent: March 11, 2008
    Assignee: Diagnostic Hybrids, Inc.
    Inventors: David R. Scholl, Francesco Saverio Ambesi-Impiombato, James L. Brown, Leonard D. Kohn, Joseph A. Jollick, Jr.
  • Systems for detection and production of respiratory, herpes and enteric viruses
    Publication number: 20070065939
    Abstract: The present invention generally relates to the field of diagnostic microbiology, and, more particularly to compositions and methods for detecting and differentiating one or more viruses or other intracellular parasites present in a specimen. The present invention also provides compositions and methods to evaluate the susceptibility of organisms to antimicrobial agents.
    Type: Application
    Filed: April 28, 2006
    Publication date: March 22, 2007
    Applicants: University Hospitals of Cleveland, Diagnostic Hybrids, Inc.
    Inventors: Yung Huang, Joseph Jollick
  • Methods for detection and production of influenza viruses
    Publication number: 20060286667
    Abstract: The present invention generally relates to the field of diagnostic microbiology, and, more particularly; to compositions and methods for detecting and differentiating one or more viruses or other intracellular parasites present in a specimen. The present invention also provides compositions and methods to evaluate the susceptibility of organisms to antimicrobial agents.
    Type: Application
    Filed: April 28, 2006
    Publication date: December 21, 2006
    Applicants: Diagnostic Hybrids, Inc., University Hospitals of Cleveland
    Inventors: David Scholl, Yung Huang, Patricia Goodrum
  • Compositions and methods for detecting severe acute respiratory syndrome coronavirus
    Patent number: 7129042
    Abstract: The invention provides compositions and methods for detecting the presence of SARS-coronavirus, for screening anti-SARS coronavirus agents and vaccines, and for reducing infection with plus-strand RNA viruses such as SARS-coronavirus.
    Type: Grant
    Filed: November 3, 2003
    Date of Patent: October 31, 2006
    Assignees: Diagnostic Hybrids, Inc., Health Research Incorporated
    Inventors: Laura Gillim-Ross, Jill Taylor, David R. Scholl, David E. Wentworth, Joseph D. Jollick
  • Mixed cell diagnostic systems for detection of respiratory, herpes and enteric viruses
    Publication number: 20060094105
    Abstract: The present invention generally relates to the field of diagnostic microbiology, and, more particularly, to compositions and methods for detecting and differentiating one or more viruses or other intracellular parasites present in a specimen. The present invention also provides compositions and methods to evaluate the susceptibility of organisms to antimicrobial agents.
    Type: Application
    Filed: September 20, 2005
    Publication date: May 4, 2006
    Applicants: University Hospitals of Cleveland, Diagnostic Hybrids, Inc.
    Inventors: Yung Huang, Joseph Jollick
  • Mixed cell diagnostic systems
    Patent number: 6946291
    Abstract: The present invention generally relates to the field of diagnostic microbiology, and, more particularly, to compositions and methods for detecting and differentiating one or more viruses or other intracellular parasites present in a specimen. The present invention also provides compositions and methods to evaluate the susceptibility of a organisms to antimicrobial agents.
    Type: Grant
    Filed: March 30, 2004
    Date of Patent: September 20, 2005
    Assignees: University Hospitals of Cleveland, Diagnostic Hybrids, Inc.
    Inventors: David R. Scholl, Patricia Gail Ray Goodrum, Yung T. Huang
  • Compositions and methods for detecting severe acute respiratory syndrome coronavirus
    Publication number: 20050095582
    Abstract: The invention provides compositions and methods for detecting the presence of SARS-coronavirus, for screening anti-SARS coronavirus agents and vaccines, and for reducing infection with plus-strand RNA viruses such as SARS-coronavirus.
    Type: Application
    Filed: November 3, 2003
    Publication date: May 5, 2005
    Applicants: Diagnostic Hybrids, Inc., Health Research Incorporated
    Inventors: Laura Gillim-Ross, Jill Taylor, David Scholl, David Wentworth, Joseph Jollick
  • Mixed cell diagnostic systems
    Patent number: 6875600
    Abstract: The present invention generally relates to the field of diagnostic microbiology, and, more particularly, to compositions and methods for detecting and differentiating one or more viruses or other intracellular parasites present in a specimen. The present invention also provides compositions and methods to evaluate the susceptibility of a organisms to antimicrobial agents.
    Type: Grant
    Filed: April 4, 2003
    Date of Patent: April 5, 2005
    Assignees: Diagnostic Hybrids, Inc., University Hospitals of Cleveland
    Inventors: David R. Scholl, Yung T. Huang, Patricia Gail Ray Goodrum
  • Diagnosis of autoimmune disease
    Patent number: 6852546
    Abstract: The present invention provides methods and compositions useful in the diagnosis and management of autoimmune diseases. In particular, the present invention provides improved methods and compositions for the diagnosis and management of Graves' disease. The methods of the present invention avoid the need for radioactivity and are much simpler, economical, and rapid than methods traditionally used for the diagnosis of Graves' disease.
    Type: Grant
    Filed: March 30, 2000
    Date of Patent: February 8, 2005
    Assignee: Diagnostic Hybrids, Inc.
    Inventor: James L. Brown
  • Mixed cell diagnostic systems
    Patent number: 6573080
    Abstract: The present invention generally relates to the field of diagnostic microbiology, and, more particularly, to compositions and methods for detecting and differentiating one or more viruses or other intracellular parasites present in a specimen. The present invention also provides compositions and methods to evaluate the susceptibility of a organisms to antimicrobial agents.
    Type: Grant
    Filed: August 9, 2001
    Date of Patent: June 3, 2003
    Assignees: Diagnostic Hybrids, Inc., University Hospitals of Cleveland
    Inventors: David R. Scholl, Yung T. Huang, Patricia Gail Ray Goodrum
  • Mixed cell diagnostic systems
    Publication number: 20030087418
    Abstract: The present invention generally relates to the field of diagnostic microbiology, and, more particularly, to compositions and methods for detecting and differentiating one or more viruses or other intracellular parasites present in a specimen. The present invention also provides compositions and methods to evaluate the susceptibility of a organisms to antimicrobial agents.
    Type: Application
    Filed: August 9, 2001
    Publication date: May 8, 2003
    Applicant: Diagnostic Hybrids, Inc.
    Inventors: David R. Scholl, Yung T. Huang, Patricia Gail Ray Goodrum
  • Mixed cell diagnostic systems
    Patent number: 6495316
    Abstract: The present invention generally relates to the field of diagnostic microbiology, and, more particularly, to compositions and methods for detecting and differentiating one or more viruses or other intracellular parasites present in a specimen. The present invention also provides compositions and methods to evaluate the susceptibility of a organisms to antimicrobial agents.
    Type: Grant
    Filed: August 10, 2001
    Date of Patent: December 17, 2002
    Assignees: Diagnostic Hybrids, Inc., University Hospitals of Cleveland
    Inventors: David R. Scholl, Yung T. Huang, Patricia Gail Ray Goodrum
  • In situ growth, freezing and testing of cultured cells
    Patent number: 6472206
    Abstract: The present invention provides methods and compositions for the in situ growth, freezing and testing of cultured cells. In particular, the present invention provides methods and compositions for the long-term preservation of cells in ready-to-use formats for testing. In addition, the present invention provides rapid and easy to use means to diagnose viral and other infections. Furthermore, the present invention provides easy to use means to grow and store cells in situ for testing methods. Indeed, the present invention makes viral, chlamydial and other diagnostic methods accessible to small laboratories, including those without cell culture capabilities.
    Type: Grant
    Filed: April 28, 2000
    Date of Patent: October 29, 2002
    Assignees: Interthyr Corporation, Diagnostic Hybrids, Inc.
    Inventors: David R. Scholl, Francesco Saverio Ambesi-Impiombato, James L. Brown, Leonard D. Kohn, Joseph A. Jollick, Jr.
  • Mixed cell diagnostic systems
    Patent number: 6406842
    Abstract: The present invention generally relates to the field of diagnostic microbiology, and, more particularly, to compositions and methods for detecting and differentiating one or more viruses or other intracellular parasites present in a specimen. The present invention also provides compositions and methods to evaluate the susceptibility of a organisms to antimicrobial agents.
    Type: Grant
    Filed: May 1, 2001
    Date of Patent: June 18, 2002
    Assignees: Diagnostic Hybrids, Inc., University Hospitals of Cleveland
    Inventors: David R. Scholl, Yung T. Huang, Patricia Gail Ray Goodrum
  • Mixed cell diagnostic systems
    Patent number: 6376172
    Abstract: The present invention generally relates to the field of diagnostic microbiology, and, more particularly, to compositions and methods for detecting and differentiating one or more viruses or other intracellular parasites present in a specimen. The present invention also provides compositions and methods to evaluate the susceptibility of a organisms to antimicrobial agents.
    Type: Grant
    Filed: September 14, 2000
    Date of Patent: April 23, 2002
    Assignees: Diagnostic Hybrids, Inc., University Hospitals of Cleveland
    Inventors: David R. Scholl, Yung T. Huang, Patricia Gail Ray Goodrum
  • Mixed cell diagnostic systems
    Publication number: 20020006610
    Abstract: The present invention generally relates to the field of diagnostic microbiology, and, more particularly, to compositions and methods for detecting and differentiating one or more viruses or other intracellular parasites present in a specimen. The present invention also provides compositions and methods to evaluate the susceptibility of a organisms to antimicrobial agents.
    Type: Application
    Filed: June 28, 2001
    Publication date: January 17, 2002
    Applicant: Diagnostic Hybrids, Inc.
    Inventors: David R. Scholl, Yung T. Huang, Patricia Gail Ray Goodrum
  • Mixed cell diagnostic systems
    Publication number: 20010036628
    Abstract: The present invention generally relates to the field of diagnostic microbiology, and, more particularly, to compositions and methods for detecting and differentiating one or more viruses or other intracellular parasites present in a specimen. The present invention also provides compositions and methods to evaluate the susceptibility of a organisms to antimicrobial agents.
    Type: Application
    Filed: May 1, 2001
    Publication date: November 1, 2001
    Applicant: DIAGNOSTIC HYBRIDS, INC.
    Inventors: David R. Scholl, Yung T. Huang, Patricia Gail Ray Goodrum
  • Mixed cell diagnostic systems
    Publication number: 20010034022
    Abstract: The present invention generally relates to the field of diagnostic microbiology, and, more particularly, to compositions and methods for detecting and differentiating one or more viruses or other intracellular parasites present in a specimen. The present invention also provides compositions and methods to evaluate the susceptibility of a organisms to antimicrobial agents.
    Type: Application
    Filed: May 1, 2001
    Publication date: October 25, 2001
    Applicant: DIAGNOSTIC HYBRIDS, INC.
    Inventors: David R. Scholl, Yung T. Huang, Patricia Gail Ray Goodrum
  • Mixed cell diagnostic systems
    Patent number: 6306582
    Abstract: The present invention generally relates to the field of diagnostic microbiology, and, more particularly, to compositions and methods for detecting and differentiating one or more viruses or other intracellular parasites present in a specimen. The present invention also provides compositions and methods to evaluate the susceptibility of a organisms to antimicrobial agents.
    Type: Grant
    Filed: April 19, 2000
    Date of Patent: October 23, 2001
    Assignees: Diagnostics Hybrids, Inc., University Hospitals of Cleveland
    Inventors: David R. Scholl, Yung T. Huang, Patricia Gail Ray Goodrum