Abstract: Advanced cervical cancer screening methods that provide a molecular based process of detecting HPV-integration. The disclosed methods allow for a streamlined approach of conducting a Pap test and immunohistochemical test on the same slide. The disclosed methods provides an inexpensive, highly sensitive, specific, and detailed test that is easy to evaluate and follow-up.
Abstract: A cell collector and cell collection method are provided for collecting clusters of cells for subsequent analysis of the cells to screen for abnormalities. The cell collector is designed to enhance the capability of the collector to pick-up clusters or clumps of cells, and to facilitate transfer of the collected clusters of cells onto a receiving structure, for example a slide. In one embodiment, a combination of the material of the collector, the texture of the collection surface of the collector, and the use of expansion and rotation of the collector during collection facilitate the collection of the clusters of cells.
Type:
Application
Filed:
December 19, 2008
Publication date:
April 23, 2009
Applicant:
DIAMICS, INC.
Inventors:
Peter GOMBRICH, Eugene DIMONTE, Edward EATON, Eric LARSON
Abstract: Systems and methods of interrogating clusters of cells for two or more biological markers that do not, or rarely, occur in the same cell during normal cellular growth, development and function, to indicate the existence of cells that are part of a local area where a pre-neoplastic or neoplastic lesion may be present. The relationship among cells is maintained while interrogating the clusters of cells to facilitate the examination and determination of the existence of possible dysplasia.
Type:
Application
Filed:
September 22, 2008
Publication date:
January 15, 2009
Applicant:
DIAMICS, INC.
Inventors:
Warren MALTZMAN, Peter GOMBRICH, Eugene DIMONTE, Edward Eaton, Eric LARSON
Abstract: Systems and methods of interrogating clusters of cells for two or more biological markers that do not, or rarely, occur in the same cell during normal cellular growth, development and function, to indicate the existence of cells that are part of a local area where a pre-neoplastic or neoplastic lesion may be present. The relationship among cells is maintained while interrogating the clusters of cells to facilitate the examination and determination of the existence of possible dysplasia.
Type:
Application
Filed:
December 23, 2005
Publication date:
August 24, 2006
Applicant:
DIAMICS, INC.
Inventors:
Warren Maltzman, Peter Gombrich, Eugene Dimonte, Edward Eaton, Eric Larson
Abstract: A cell collector and cell collection method are provided for collecting clusters of cells for subsequent analysis of the cells to screen for abnormalities. The cell collector is designed to enhance the capability of the collector to pick-up clusters or clumps of cells, and to facilitate transfer of the collected clusters of cells onto a receiving structure, for example a slide. In one embodiment, a combination of the material of the collector, the texture of the collection surface of the collector, and the use of expansion and rotation of the collector during collection facilitate the collection of the clusters of cells.
Type:
Application
Filed:
December 23, 2005
Publication date:
July 20, 2006
Applicant:
DIAMICS, INC.
Inventors:
Peter Gombrich, Eugene Dimonte, Edward Eaton, Eric Larson