Abstract: The invention is directed to methods for diagnosis and differentiation of neurodegenerative diseases (NDs), by quantifying miRNAs in bodily fluids.
Type:
Grant
Filed:
March 21, 2017
Date of Patent:
October 19, 2021
Assignee:
DIAMIR, LLC
Inventors:
Samuil R. Umansky, Kira S. Sheinerman, Vladimir G. Tsivinsky
Abstract: The invention is directed to methods for early diagnosis, progression and treatment monitoring of Parkinson's disease (PD) and its differentiation from other neurodegenerative diseases by quantifying brain-enriched miRNA in bodily fluids.
Type:
Grant
Filed:
November 17, 2014
Date of Patent:
August 24, 2021
Assignee:
DIAMIR, LLC
Inventors:
Samuil R. Umansky, Kira S. Sheinerman, Vladimir G. Tsivinsky
Abstract: The invention provides methods for diagnosis and monitoring of Rett syndrome and other neurodevelopmental disorders by quantitative analysis of miRNAs in bodily fluids.
Type:
Grant
Filed:
July 5, 2018
Date of Patent:
April 13, 2021
Assignee:
DIAMIR, LLC
Inventors:
Samuil R. Umansky, Kira S. Sheinerman, Vladimir G. Tsivinsky
Abstract: The present invention is directed to methods for detection, treatment monitoring, and slowing of aging by quantifying miRNAs in bodily fluids.
Type:
Grant
Filed:
July 24, 2018
Date of Patent:
September 22, 2020
Assignee:
DIAMIR, LLC
Inventors:
Kira S. Sheinerman, Vladimir G. Tsivinsky, Samuil R. Umansky
Abstract: Described are methods for early noninvasive or minimally invasive detection of pathological changes in organ systems/organs/tissues/cells by quantifying organ system-/organ-/tissue-/cells type-enriched miRNA in bodily fluids.
Type:
Grant
Filed:
May 26, 2017
Date of Patent:
November 12, 2019
Assignee:
DIAMIR, LLC
Inventors:
Samuil R. Umansky, Kira S. Sheinerman, Vladimir Tsivinsky
Abstract: Described are methods for early diagnosis and progression monitoring of Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD) by quantifying neurite and/or synapse miRNAs in bodily fluids.
Type:
Grant
Filed:
December 23, 2016
Date of Patent:
April 2, 2019
Assignee:
DiamiR, LLC
Inventors:
Samuil R. Umansky, Kira S. Sheinerman, Vladimir Tsivinsky
Abstract: The invention is directed to methods for diagnosis and differentiation of neurodegenerative diseases (NDs), by quantifying miRNAs in bodily fluids.
Type:
Application
Filed:
March 21, 2017
Publication date:
March 28, 2019
Applicant:
DIAMIR, LLC
Inventors:
Samuil R. UMANSKY, Kira S. SHEINERMAN, Vladimir G. TSIVINSKY
Abstract: The present invention is directed to methods for detection, treatment monitoring, and slowing of aging by quantifying miRNAs in bodily fluids.
Type:
Application
Filed:
July 24, 2018
Publication date:
January 24, 2019
Applicant:
DiamiR, LLC
Inventors:
Kira S. Sheinerman, Vladimir G. Tsivinsky, Samuil R. Umansky
Abstract: The invention provides methods for diagnosis and monitoring of Rett syndrome and other neurodevelopmental disorders by quantitative analysis of miRNAs in bodily fluids.
Type:
Application
Filed:
July 5, 2018
Publication date:
November 1, 2018
Applicant:
DiamiR, LLC
Inventors:
Samuil R. Umansky, Kira S. Sheinerman, Vladimir G. Tsivinsky
Abstract: Described are methods for early noninvasive or minimally invasive detection of pathological changes in organ systems/organs/tissues/cells by quantifying organ system-/organ-/tissue-/cells type-enriched miRNA in bodily fluids.
Type:
Application
Filed:
May 26, 2017
Publication date:
December 21, 2017
Applicant:
DIAMIR, LLC
Inventors:
Samuil R. Umansky, Kira S. Sheinerman, Vladimir Tsivinsky
Abstract: Described are methods for early noninvasive or minimally invasive detection of pathological changes in organ systems/organs/tissues/cells by quantifying organ system-/organ-/tissue-/cells type-enriched miRNA in bodily fluids.
Type:
Grant
Filed:
April 18, 2012
Date of Patent:
October 31, 2017
Assignee:
DiamiR, LLC
Inventors:
Samuil R. Umansky, Kira S. Sheinerman, Vladimir Tsivinsky
Abstract: Described are methods for early diagnosis and progression monitoring of Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD) by quantifying neurite and/or synapse miRNAs in bodily fluids.
Type:
Application
Filed:
December 23, 2016
Publication date:
April 20, 2017
Applicant:
DiamiR, LLC
Inventors:
Samuil R. Umansky, Kira S. Sheinerman, Vladimir Tsivinsky
Abstract: Described are methods for early diagnosis and progression monitoring of Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD) by quantifying neurite and/or synapse miRNAs in bodily fluids.
Type:
Grant
Filed:
April 18, 2012
Date of Patent:
January 31, 2017
Assignee:
DIAMIR, LLC
Inventors:
Samuil R. Umansky, Kira S. Sheinerman, Vladimir Tsivinsky
Abstract: The invention is directed to methods for early diagnosis, progression and treatment monitoring of Parkinson's disease (PD) and its differentiation from other neurodegenerative diseases by quantifying brain-enriched miRNA in bodily fluids.
Type:
Application
Filed:
November 17, 2014
Publication date:
September 22, 2016
Applicant:
DIAMIR, LLC
Inventors:
Samuil R. UMANKSY, Kira S. Sheinerman, Vladimir G. Tsivinsky
Abstract: Described are methods for detection of neuronal pathologies using quantitative analysis in bodily fluids of synapse and/or neurite small RNAs and application of these methods to early diagnosis and monitoring of neurodegenerative diseases and other neurological disorders.
Abstract: Described are methods for early noninvasive or minimally invasive detection of pathological changes in organ systems/organs/tissues/cells by quantifying organ system-/organ-/tissue-/cells type-enriched miRNA in bodily fluids.
Type:
Application
Filed:
April 18, 2012
Publication date:
September 11, 2014
Applicant:
DiamiR, LLC
Inventors:
Samuil R. Umansky, Kira S. Sheinerman, Vladimir Tsivinsky
Abstract: Described are methods for early diagnosis and progression monitoring of Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD) by quantifying neurite and/or synapse miRNAs in bodily fluids.
Type:
Application
Filed:
April 18, 2012
Publication date:
May 1, 2014
Applicant:
DIAMIR, LLC
Inventors:
Samuil R. Umansky, Kira S. Sheinerman, Vladimir Tsivinsky
Abstract: Described are methods for detection of neuronal pathologies using quantitative analysis in bodily fluids of synapse and/or neurite small RNAs and application of these methods to early diagnosis and monitoring of neurodegenerative diseases and other neurological disorders.
Abstract: Described are methods for detection of neuronal pathologies using quantitative analysis in bodily fluids of synapse and/or neurite small RNAs and application of these methods to early diagnosis and monitoring of neurodegenerative diseases and other neurological disorders.