Abstract: Provided is uses of SAA1?/?(1.5/1.5) homozygote in prognosis and/diagnosis of liver cirrhosis, and in preparation of a reagent for liver cirrhosis prognosis and/or liver cirrhosis diagnosis. Recognition of liver cirrhosis susceptible populations can be achieved by detection of human SAA1?/? homozygote and non-SAA1?/? homozygote through real-time fluorescence quantitative allele specific PCR.

Abstract: An interchangeable disposable measuring cassette for insertion into a measuring apparatus for detecting target molecules in a liquid sample by measuring fluorescence emission has a flow measurement cell in which an excitation radiation provided by the measuring apparatus produces an evanescent field in the liquid sample beyond a boundary layer for the liquid sample and the measurement cell. To be better able to ensure that no sample liquid can cross from the measurement cell into the measuring apparatus, the measuring cassette includes a body including an optically transparent material and a base in contact with the underside of the body. The measurement cell is formed by a cutout provided in the body, the base, or both. The areas on which the body and the base are on top of one another around this cutout are connected to one another directly and in fluid-tight fashion by laser welding.

Abstract: The invention concerns a method of automatically metering and mixing liquids, which mixes the liquids particularly effectively as quickly as possible and in few steps, which is simple to carry out and which is inexpensive and which does not require any additional component.