Patents Assigned to Diatos, S.A.
  • Patent number: 7884070
    Abstract: A peptide including a first peptide sequence of formula KLAKLAK (SEQ ID NO:11)in which K is lysine, L is leucine and A is alanine, and a second peptide sequence of formula (B) in which B is a peptide of 4 to 15 amino acids positively charged at neutral pH, including at least one peptide motif of formula ?xx? (SEQ ID NO:13)in which ? is a basic amino acid and X is any amino acid, and in which the first peptide sequence is repeated n times and the second peptide sequence is repeated m times, n and m being whole numbers between 1 and 5.
    Type: Grant
    Filed: January 7, 2005
    Date of Patent: February 8, 2011
    Assignee: Diatos S.A.
    Inventor: Valérie Arranz
  • Publication number: 20090220529
    Abstract: This invention relates to the field of antibody-drug conjugates, and more particularly antibody-drug conjugates that are intended for the treatment and/or diagnosis of diseases such as tumors and/or inflammatory reactions.
    Type: Application
    Filed: March 10, 2006
    Publication date: September 3, 2009
    Applicant: Diatos, S.A.
    Inventors: Andre Trouet, Vincent Dubois
  • Patent number: 7544664
    Abstract: The present invention relates to an amino acid sequence being able to facilitate penetration of a substance of interest inside cells and/or cell nuclei and having the following formula (I) [(X1)p [(X)o (B)nX B X X B]m (X2)q wherein X1 and X2 are amino acid sequences of 1 to 20 amino acids; p and q are whole numbers between 0 and 5; B is a basic amino acid; X is a non-basic, preferably hydrophobic amino acid, such as alanine, isoleucine, leucine, methionine, phenylalanine, tryptophan, valine or tyrosine; n is 2 or 3; m is 1 to 4; o is 0 or 1, between 0 and 5; B is a basic amino acid; X is a non-basic, preferably hydrophobic amino acid, such as alanine, isoleucine, leucine, methionine phenylalanine, tryptophan, valine or tyrosine; n is 2 or 3; m is 1 to 4; o is 0 or 1.
    Type: Grant
    Filed: August 13, 2004
    Date of Patent: June 9, 2009
    Assignee: Diatos, S.A.
    Inventor: Alexandre Avrameas
  • Patent number: 7112562
    Abstract: The invention relates generally to chimeric peptides and compositions that facilitate the transport of insulin across biological membranes, methods for preparing the chimeric peptides, and a method for treating a subject suffering from diabetes.
    Type: Grant
    Filed: January 9, 2006
    Date of Patent: September 26, 2006
    Assignee: Diatos, S.A.
    Inventor: Jean-Leon Tchelingerian
  • Patent number: 7049286
    Abstract: The invention relates generally to chimeric peptides and compositions that facilitate the transport of insulin across biological membranes, methods for preparing the chimeric peptides, and a method for treating a subject suffering from diabetes.
    Type: Grant
    Filed: August 29, 2002
    Date of Patent: May 23, 2006
    Assignee: Diatos, S.A.
    Inventor: Jean-Leon Tchelingerian
  • Publication number: 20050277589
    Abstract: A peptide including a first peptide sequence of formula KLAKLAK in which K is lysine, L is leucine and A is alanine, and a second peptide sequence of formula (B) in which B is a peptide of 4 to 15 amino acids positively charged at neutral pH, including at least one peptide motif of formula ?xx? in which ? is a basic amino acid and X is any amino acid, and in which the first peptide sequence is repeated n times and the second peptide sequence is repeated m times, n and m being whole numbers between 1 and 5.
    Type: Application
    Filed: January 7, 2005
    Publication date: December 15, 2005
    Applicant: Diatos S.A., a corporation of France
    Inventor: Valerie Arranz