Abstract: A novel process is described for the preparation of the active principle pantoprazole based on the use of novel intermediate compounds of general formula (I) where X is an atom of halogen and n=0 or 1, so that when n=1, the intermediate compounds are methoxylated, and when n=0 said intermediate compounds are first oxidized to n=1 and thereafter are methoxylated. Also described are the novel intermediates, as well as the process for the preparation thereof.
Type:
Grant
Filed:
October 1, 2001
Date of Patent:
June 13, 2006
Assignee:
Dinamite Dipharma (Dipharma S.P.A.)
Inventors:
Pilar Sturla De Palomo, legal representative, Deborah Palomo Sturla, legal representative, Alberto Palomo Sturla, legal representative, Alberto Palomo Coll, deceased