Abstract: A wire terminal block coupling separation member (1) is provided and includes an insulative housing (10), separation members (20) and conductive wire and terminal crimping members (30). The separation member (20) is secured to the insulative housing and includes a base (21) and a pressing mechanism (22) operably connected to the base (21). The pressing mechanism (22) includes a pressing portion (221) and a tail portion (222) extended outward from the pressing portion (221). The conductive wire and terminal crimping members (30) are arranged inside the insulative housing (10). When an acting force is exerted on the pressing portion (221), the pressing mechanism (22) generates deformation to drive the tail portion (222) to ascend. Accordingly, the pressing operation of the wire terminal block coupling separation member (1) is facilitated, and it is equipped with simple structure for easy installation.