Patents Assigned to Dinona Inc.
-
Patent number: 9746474Abstract: The present invention relates to a CD43 epitope expressed on human acute leukemia and lymphoblastic lymphoma cells and its use. More particularly, the present invention relates to a CD43 epitope expressed on human acute leukemia, lymphoblastic lymphoma cells, but not on mature hematopoietic cells, hematopoietic stem cells and non-hematopoietic cells, and to its diagnostic and therapeutic application on acute leukemia and lymphoblastic lymphoma.Type: GrantFiled: May 2, 2014Date of Patent: August 29, 2017Assignee: DINONA INC.Inventors: Seong-Hoe Park, Kyeong-Cheon Jung, Eun-Young Choi, Seong-Pyo Park
-
Patent number: 9115198Abstract: The present invention relates to an antibody binding to human intercellular adhesion molecule-1 (ICAM-1) where the antibody is able to modulate the differentiation status of dendritic cells and prolong the graft survival. In addition, the present invention provides a pharmaceutical composition comprising the antibody, and method of using them for the treatment of disease.Type: GrantFiled: November 22, 2012Date of Patent: August 25, 2015Assignee: Dinona Inc.Inventors: Seong-Hoe Park, Kyeong-Cheon Jung, Youngmee Bae, Seong-Pyo Park, Yoon-Kyung Jeon
-
Patent number: 8900586Abstract: The present invention relates to an antibody binding to the domain 2 of human intercellular adhesion molecules-1 (ICAM-1) where the antibody is able to modulate the differentiation status of dendritic cells and induce antigen-specific T cell tolerance, thereby be effective in the prevention and/or treatment of T cell-mediated immune disorders such as transplantation rejection, graft-versus-host disease, and autoimmune disease. In addition, the present invention provides a pharmaceutical composition comprising the antibody, and method of using them for the treatment of disease.Type: GrantFiled: July 5, 2011Date of Patent: December 2, 2014Assignees: Dinona Inc., SNU R&DB FoundationInventors: Seong Hoe Park, Kyeong Cheon Jung
-
Publication number: 20140342374Abstract: The present invention relates to a CD43 epitope expressed on human acute leukemia and lymphoblastic lymphoma cells and its use. More particularly, the present invention relates to a CD43 epitope expressed on human acute leukemia, lymphoblastic lymphoma cells, but not on mature hematopoietic cells, hematopoietic stem cells and non-hematopoietic cells, and to its diagnostic and therapeutic application on acute leukemia and lymphoblastic lymphoma.Type: ApplicationFiled: May 2, 2014Publication date: November 20, 2014Applicant: Dinona Inc.Inventors: Seong-Hoe Park, Kyeong-Cheon Jung, Eun-Young Choi, Seong-Pyo Park
-
Patent number: 8753636Abstract: The present invention relates to a CD43 epitope expressed on human acute leukemia and lymphoblastic lymphoma cells and its use. More particularly, the present invention relates to a CD43 epitope expressed on human acute leukemia, lymphoblastic lymphoma cells, but not on mature hematopoietic cells, hematopoietic stem cells and non-hematopoietic cells, and to its diagnostic and therapeutic application on acute leukemia and lymphoblastic lymphoma.Type: GrantFiled: March 15, 2013Date of Patent: June 17, 2014Assignee: Dinona Inc.Inventors: Seong-Hoe Park, Kyeong-Cheon Jung, Eun-Young Choi, Seong-Pyo Park
-
Publication number: 20140148583Abstract: The present invention relates to an antibody binding to the domain 2 of human intercellular adhesion molecules-1 (ICAM-1) where the antibody is able to modulate the differentiation status of dendritic cells and induce antigen-specific T cell tolerance, thereby be effective in the prevention and/or treatment of T cell-mediated immune disorders such as transplantation rejection, graft-versus-host disease, and autoimmune disease. In addition, the present invention provides a pharmaceutical composition comprising the antibody, and method of using them for the treatment of disease.Type: ApplicationFiled: July 5, 2011Publication date: May 29, 2014Applicants: SNU R&DB FOUNDATION, DINONA INC.Inventors: Seong Hoe Park, Kyeong Cheon Jung
-
Patent number: 8546093Abstract: The present invention relates to an antibody against a protein specifically expressed in methicillin-resistant strains of Staphylococcus aureus (MRSA), and a method and a kit for detecting MRSA. The present invention enables a fast and accurate detection of MRSA by using both a PBP2a-specific antibody for the detection of PBP2a and a Protein A-specific antibody for the detection of Protein A.Type: GrantFiled: June 24, 2009Date of Patent: October 1, 2013Assignee: Dinona Inc.Inventors: Hyung-Geun Song, Sang-Soon Yoon, Hae-Jung Kim, Gil-Yong Jee, Mi-Hyang Shin, Yu-Ri Moon
-
Publication number: 20130142811Abstract: The present invention relates to an antibody binding to human intercellular adhesion molecule-1 (ICAM-1) where the antibody is able to modulate the differentiation status of dendritic cells and prolong the graft survival. In addition, the present invention provides a pharmaceutical composition comprising the antibody, and method of using them for the treatment of disease.Type: ApplicationFiled: November 22, 2012Publication date: June 6, 2013Applicant: DINONA INC.Inventor: Dinona Inc.
-
Patent number: 8426555Abstract: The present invention relates to a CD43 epitope expressed on human acute leukemia and lymphoblastic lymphoma cells and its use. More particularly, the present invention relates to a CD43 epitope expressed on human acute leukemia, lymphoblastic lymphoma cells, but not on mature hematopoietic cells, hematopoietic stem cells and non-hematopoietic cells, and to its diagnostic and therapeutic application on acute leukemia and lymphoblastic lymphoma.Type: GrantFiled: October 9, 2009Date of Patent: April 23, 2013Assignee: Dinona Inc.Inventors: Seong-Hoe Park, Kyeong-Cheon Jung, Eun-Young Choi, Seong-Pyo Park
-
Patent number: 8404812Abstract: The present invention relates to epitope of CD66c specific to lung adenocarcinoma and antibody recognizing the same. The present invention relates to identifying epitope of CD66c specific to lung adenocarcinoma, antibody recognizing the same, cell lines producing the same and the applications in diagnosis, prevention and treatment of lung adenocarcinoma by using the same. The above CD66c epitope is specific to lung adenocarcinoma cells, and therefore the antibody or its fragment recognizing the epitope can be used in compositions to diagnose, treat and prevent lung adenocarcinoma cells.Type: GrantFiled: August 26, 2010Date of Patent: March 26, 2013Assignee: Dinona Inc.Inventors: Hyung-Geun Song, Sang-Sun Yoon, Mi-Hyang Shin, Yu-Ri Moon
-
Publication number: 20120083589Abstract: The present invention relates to an antibody binding to human intercellular adhesion molecule-1 (ICAM-1) where the antibody is able to modulate the differentiation status of dendritic cells and prolong the graft survival. In addition, the present invention provides a pharmaceutical composition comprising the antibody, and method of using them for the treatment of disease.Type: ApplicationFiled: August 10, 2011Publication date: April 5, 2012Applicant: DINONA INC.Inventors: Seong-Hoe Park, Kyeong-Cheon Jung, Youngmee Bae, Seong-Pyo Park, Yoon-Kyung Jeon
-
Publication number: 20120070851Abstract: The present invention relates to an antibody against a protein specifically expressed in methicillin-resistant strains of Staphylococcus aureus (MRSA), and a method and a kit for detecting MRSA. The present invention enables a fast and accurate detection of MRSA by using both a PBP2a-specific antibody for the detection of PBP2a and a Protein A-specific antibody for the detection of Protein A.Type: ApplicationFiled: June 24, 2009Publication date: March 22, 2012Applicant: DiNonA Inc.Inventors: Hyung-Geun Song, Sang-Soon Yoon, Hae-Jung Kim, Gil-Yong Jee, Mi-Hyang Shin, Yu-Ri Moon
-
Patent number: 8026343Abstract: The present invention relates to an antibody binding to human intercellular adhesion molecule-1 (ICAM-1) where the antibody is able to modulate the differentiation status of dendritic cells and prolong the graft survival. In addition, the present invention provides a pharmaceutical composition comprising the antibody, and method of using them for the treatment of disease.Type: GrantFiled: March 24, 2009Date of Patent: September 27, 2011Assignee: Dinona Inc.Inventors: Seong-Hoe Park, Kyeong-Cheon Jung, Youngmee Bae, Seong-Pyo Park, Yoon-Kyung Jeon
-
Publication number: 20110212095Abstract: The present invention relates to epitope of CD66c specific to lung adenocarcinoma and antibody recognizing the same. The present invention relates to identifying epitope of CD66c specific to lung adenocarcinoma, antibody recognizing the same, cell lines producing the same and the applications in diagnosis, prevention and treatment of lung adenocarcinoma by using the same. The above CD66c epitope is specific to lung adenocarcinoma cells, and therefore the antibody or its fragment recognizing the epitope can be used in compositions to diagnose, treat and prevent lung adenocarcinoma cells.Type: ApplicationFiled: August 26, 2010Publication date: September 1, 2011Applicant: DiNonA Inc.Inventors: Hyung-Geun SONG, Sang-Sun Yoon, Mi-Hyang Shin, Yu-Ri Moon
-
Publication number: 20100234562Abstract: The present invention relates to a CD43 epitope expressed on human acute leukemia and lymphoblastic lymphoma cells and its use. More particularly, the present invention relates to a CD43 epitope expressed on human acute leukemia, lymphoblastic lymphoma cells, but not on mature hematopoietic cells, hematopoietic stem cells and non-hematopoietic cells, and to its diagnostic and therapeutic application on acute leukemia and lymphoblastic lymphoma.Type: ApplicationFiled: October 9, 2009Publication date: September 16, 2010Applicant: DINONA INC.Inventors: SEONG-HOE PARK, KYEONG-CHEON JUNG, EUN-YOUNG CHOI, SEONG-PYO PARK
-
Patent number: 7622560Abstract: The present invention relates to a CD43 epitope expressed on human acute leukemia and lymphoblastic lymphoma cells and its use. More particularly, the present invention relates to a CD43 epitope expressed on human acute leukemia, lymphoblastic lymphoma cells, but not on mature hematopoietic cells, hematopoietic stem cells and non-hematopoietic cells, and to its diagnostic and therapeutic application on acute leukemia and lymphoblastic lymphoma.Type: GrantFiled: December 20, 2005Date of Patent: November 24, 2009Assignee: Dinona Inc.Inventors: Seong-Hoe Park, Kyeong-Cheon Jung, Eun-Young Choi, Seong-Pyo Park
-
Publication number: 20080300582Abstract: A laser skin perforator and a method of forming a skin hole using a laser that forms a plurality of micro holes in skin using the laser when treating various skin diseases such as removing a wrinkle and a scar of skin are provided. The laser skin perforator includes a main laser oscillator, an optical unit, an area display laser oscillator, a shutter unit, and a laser emission unit. Further, the method of forming a skin hole using a laser includes setting a surgical operation area, radiating an area display laser beam, setting an emission value of a main laser beam, setting the pulse number of the main laser beam, and forming a micro hole in skin by radiating the main laser beam of the set pulse number.Type: ApplicationFiled: April 22, 2008Publication date: December 4, 2008Applicant: DiNonA Inc.Inventor: Man-Su PARK