Patents Assigned to DiPharma S.A.
  • Stable solid pharmaceutical formulations containing 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cylcohexanedione
    Patent number: 10888527
    Abstract: The present invention relates to highly stable drug dosage forms comprising. The invention also contemplates said highly stable drug dosage forms for the treatment of diseases where inhibition of 4-hydroxyphenylpyruvate dioxygenase 5 will result at improving the health of the patient.
    Type: Grant
    Filed: February 9, 2017
    Date of Patent: January 12, 2021
    Assignee: DIPHARMA S.A.
    Inventors: Chiara Conti, Salvatore Agostino Giammillari, Giuseppe Maccari
  • Stable Solid Pharmaceutical Formulations Containing 2-(2-Nitro-4-Trifluoromethylbenzoyl)-1,3-Cylcohexanedione
    Publication number: 20190160014
    Abstract: The present invention relates to highly stable drug dosage forms comprising. The invention also contemplates said highly stable drug dosage forms for the treatment of diseases where inhibition of 4-hydroxyphenylpyruvate dioxygenase 5 will result at improving the health of the patient.
    Type: Application
    Filed: February 9, 2017
    Publication date: May 30, 2019
    Applicant: Dipharma S.A.
    Inventors: Chiara CONTI, Salvatore Agostino GIAMMILLARI, Giuseppe MACCARI
  • Crystalline inhibitor of 4-hydroxyphenylpyruvate dioxygenase
    Patent number: 10093610
    Abstract: The present invention relates to an improved synthesis and crystallization process of the 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione, also known as nitisinone or NTBC.
    Type: Grant
    Filed: September 14, 2017
    Date of Patent: October 9, 2018
    Assignee: DIPHARMA S.A.
    Inventor: Emanuele Attolino
  • Crystalline Inhibitor of 4-Hydroxyphenylpyruvate Dioxygenase
    Publication number: 20180148402
    Abstract: The present invention relates to an improved synthesis and crystallization process of the 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione, also known as nitisinone or NTBC.
    Type: Application
    Filed: September 14, 2017
    Publication date: May 31, 2018
    Applicant: Dipharma S.A.
    Inventor: Emanuele ATTOLINO
  • Crystalline inhibitor of 4-hydroxyphenylpyruvate dioxygenase, and a process of synthesis and crystallization thereof
    Patent number: 9783485
    Abstract: The present invention relates to an improved synthesis and crystallization process of the 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione, also known as nitisinone or NTBC.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: October 10, 2017
    Assignee: Dipharma S.A.
    Inventor: Emanuele Attolino
  • Stable compositions of tetrahydrobiopterin
    Patent number: 9492451
    Abstract: The present invention relates to stable pharmaceutical compositions of tetrahydrobiopterin and processes for producing such compositions. Particularly the present invention relates to stable pharmaceutical compositions comprising tetrahydrobiopterin and at least one stabilizing agent.
    Type: Grant
    Filed: March 1, 2012
    Date of Patent: November 15, 2016
    Assignee: DiPharma S.A.
    Inventors: Maharukh Tehmasp Rustomjee, Anilkumar Surendrakumar Gandhi