Patents Assigned to Director-General of Agency of Industrial Science & Technology an organ of The Ministry of Industrial Trade and Industry of Japan
  • Transformed yeasts having steroid-hydroxylase activity and process for hydroxylation of steroids using the said transformed yeasts
    Patent number: 5137822
    Abstract: Transformed yeasts with yeast expression plasmid containing yeast alcohol dehydrogenase promoter and bovine adrenocortical cytochrome P-450.sub.17.alpha. cDNA, which produce bovine adrenocortical cytochrome P-450.sub.17.alpha., and processes for producing 17-hydroxypregnenolone and 17-hydroxyprogesterone which comprises 17-hydroxylating pregnenolone or progesterone to 17-hydroxypregnenolone or 17-hydroxyprogesterone, respectively, with the said transformed yeasts.
    Type: Grant
    Filed: August 16, 1988
    Date of Patent: August 11, 1992
    Assignee: Director-General of Agency of Industrial Science & Technology an organ of The Ministry of Industrial Trade and Industry of Japan
    Inventors: Yoshiyasu Yabusaki, Toshiyuki Sakaki, Megumi Shibata, Hideo Ohkawa