Abstract: A recombinant flavocytochrome b2 (FCb2), comprising a mature FCb2 peptide sequence of a native FCb2, or a functionally active variant of said mature FCb2 peptide sequence, wherein the N-terminus of said mature FCb2 peptide sequence consists of a truncated signal peptide sequence replacing the native signal peptide sequence, and wherein said truncated signal peptide sequence is of the following structure from N- to C-terminus: i. a methionine; ii. optionally a tag sequence; iii. an amino acid sequence of a length of 0-9 amino acids of the native signal peptide sequence, corresponding to the amino acid sequence up to 9 amino acids directly upstream of the I/L/V-x-N/A/L motif of the native signal peptide sequence of FCb2; and iv. the I/L/V-x-N/A/L motif, which can be of number 0, 1, or can be partially truncated, wherein if the number is 0 or the I/L/V-x-N/A/L is partially truncated, the length of the amino acid sequence of iii.

Abstract: The present invention relates to a modified cellobiose dehydrogenase (CDH) or its functional flavodehydrogenase domain having glucose oxidation activity and a reduced maltose oxidation activity as compared to the unmodified CDH or its functional flavodehydrogenase domain, nucleic acids encoding said enzyme or domain, electrodes with said enzyme or domain and methods of producing and using the same.

Abstract: The present invention relates to cellobiose dehydrogenases (CDH) having glucose oxidation activity at a pH of 7.4 or above, modifications to modify the pH dependency of the enzymes activity, uses for these CDHs, in particular electrode sensors and electrochemical cells.

Abstract: The present invention relates to cellobiose dehydrogenases (CDH) having glucose oxidation activity at a pH of 7.4 or above, modifications to modify the pH dependency of the enzymes activity, uses for these CDHs, in particular electrode sensors and electrochemical cells.

Abstract: The present invention relates to cellobiose dehydrogenases (CDH) having glucose oxidation activity at a pH of 7.4 or above, modifications to modify the pH dependency of the enzymes activity, uses for these CDHs, in particular electrode sensors and electrochemical cells.

Abstract: The present invention relates to cellobiose dehydrogenases (CDH) having glucose oxidation activity at a pH of 7.4 or above, modifications to modify the pH dependency of the enzymes activity, uses for these CDHs, in particular electrode sensors and electrochemical cells.