Abstract: The present disclosure relates to discogenic cell populations, methods of deriving, and methods of using them. The presently described discogenic cell populations may be used to restore or regenerate damaged, diseased, or missing intervertebral discs of a subject. The presently described discogenic cell populations can be derived from and administered or implanted into a subject, or may be derived from an unrelated donor.
Abstract: This invention provides an isolated disc stem cell population, compositions, and methods of obtaining and growing the same. Moreover, this invention provides an isolated discosphere, compositions, and methods of obtaining and growing the same. An artificial disc containing the cells of the present invention is provided together with methods of making the same. This invention also provides a method of treating a subject having a herniated disc utilizing the cells and methods of the invention.
Type:
Grant
Filed:
November 8, 2016
Date of Patent:
November 9, 2021
Assignee:
DiscGenics, Inc.
Inventors:
Valery Kukekov, Christopher Duntsch, Tatyana Ignatova
Abstract: This invention provides disc stem cells, processes for obtaining and culturing disc stem cells, and methods for repairing damaged or diseased disc tissue comprising the use of the disc stem cells of the invention.
Type:
Grant
Filed:
May 22, 2017
Date of Patent:
April 28, 2020
Assignee:
DiscGenics, Inc.
Inventors:
Valery Kukekov, Umar Akbar, Christopher Duntsch
Abstract: This invention provides disc stem cells, processes for obtaining and culturing disc stem cells, and methods for repairing damaged or diseased disc tissue comprising the use of the disc stem cells of the invention.
Type:
Grant
Filed:
February 14, 2012
Date of Patent:
May 23, 2017
Assignee:
DISCGENICS
Inventors:
Valery Kukekov, Umar Akbar, Christopher Duntsch
Abstract: This invention provides an isolated disc stem cell population, compositions, and methods of obtaining and growing the same. Moreover, this invention provides an isolated discosphere, compositions, and methods of obtaining and growing the same. An artificial disc containing the cells of the present invention is provided together with methods of making the same. This invention also provides a method of treating a subject having a herniated disc utilizing the cells and methods of the invention.
Type:
Grant
Filed:
December 21, 2011
Date of Patent:
November 8, 2016
Assignee:
DISCGENICS
Inventors:
Valery Kukekeov, Christopher Duntsch, Tatyana Igantova
Abstract: This invention provides disc stem cells, processes for obtaining and culturing disc stein cells, and methods for repairing damaged or diseased disc tissue comprising the use of the disc stem cells of the invention.
Type:
Application
Filed:
February 14, 2012
Publication date:
April 2, 2015
Applicant:
DISCGENICS
Inventors:
Valery Kukekov, Umar Akbar, Christopher Duntsch
Abstract: The present disclosure relates to discogenic cell populations, methods of deriving, and methods of using them. The presently described discogenic cell populations may be used to restore or regenerate damaged, diseased, or missing intervertebral discs of a subject. The presently described discogenic cell populations can be derived from and administered or implanted into a subject, or may be derived from an unrelated donor.
Abstract: This invention provides disc stem cells, processes for obtaining and culturing disc stem cells, and methods for repairing damaged or diseased disc tissue comprising the use of the disc stem cells of the invention.
Type:
Application
Filed:
March 24, 2014
Publication date:
September 25, 2014
Applicant:
DISCGENICS
Inventors:
Valery Kukekov, Umar Akbar, Christopher Duntsch
Abstract: This invention provides an isolated disc stem cell population, compositions, and methods of obtaining and growing the same. Moreover, this invention provides an isolated discosphere, compositions, and methods of obtaining and growing the same. An artificial disc containing the cells of the present invention is provided together with methods of making the same. This invention also provides a method of treating a subject having a herniated disc utilizing the cells and methods of the invention.
Type:
Grant
Filed:
July 7, 2008
Date of Patent:
July 24, 2012
Assignee:
Discgenics
Inventors:
Valery Kukekeov, Christopher Duntsch, Tatyana Igantova