Abstract: The present invention provides DNA constructs, transgenic plants containing such constructs, and methods of making the plants. The DNA constructs encode a polypeptide that when expressed results in the production of fatty acid compounds having anthelmintic activity. Transgenic plants expressing such a polypeptide can exhibit enhanced resistance to plant parasitic nematodes, particularly when expressed in vegetative tissues. Transgenic plants expressing such a polypeptide can also be useful for non-pesticidal industrial uses.
Type:
Application
Filed:
October 25, 2006
Publication date:
July 19, 2007
Applicant:
Divergence, Inc., a Delaware corporation
Inventors:
Michelle Verbsky, Catherine Baublite, Andrew Kloek, Jennifer Davila-Aponte, Michelle Hresko, Merry McLaird, Rodolfo Zentella, Deryck Williams
Abstract: Disclosed are two nucleic acid molecules from M. incognita encoding malate dehydrogenase-like (MDH-like) polypeptides. The MDH-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of MDH-like nucleotides and polypeptides. The invention further relates to screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
Type:
Application
Filed:
April 6, 2004
Publication date:
November 25, 2004
Applicant:
Divergence, Inc., a Delaware corporation
Inventors:
Andrew P. Kloek, Brandy Salmon, Deryck Jeremy Williams