Abstract: An aqueous water miscible composition composed of carboxylic acid diesters and a fatty acid salt. The fatty acid salt may be represented by the formula: R1COO−X+  (I) wherein R1 is a C6 to C19 hydrocarbyl group, optionally substituted with one or more hydroxyl or C1-C5 hydrocarbyl groups; and X is ammonium or an alkali metal. The carboxylic acid diester may be represented by the formula: ROOC(CH2)nCOOR′  (II) wherein R and R′ are independently selected from a C1 to C8 alkyl group and n is from 1 to 8.

Abstract: Omapatrilat (I) is a potent inhibitor of angiotensin-converting enzyme (ACE) and neutral endopeptidase (NEP) both in vitro and in vivo and is currently undergoing large scale clinical trials as an anti-hypertensive. Omapatrilat may be synthesized using the S-stereoisomer of compound (V). Compound (V) may be prepared from a novel hydantoin (III). The hydantoin may be prepared from a monoacetal (XI) or via a dinitrile (V).

Abstract: Omapatrilat (I) is a potent inhibitor of angiotensin-converting enzyme (ACE) and neutral endopeptidase (NEP) both in vitro and in vivo and is currently undergoing large scale clinical trials as an anti-hypertensive. Omapatrilat may be synthesized using the S-stereoisomer of a racemic mixture. The racemic mixture may be prepared from a hydantoin (III). The hydantoin may be prepared from a novel dinitrile compound (IV): The dinitrile may be produced by reacting a monoacetal with a non-carbonate ammonium salt and an alkali cyanide.

Abstract: A heat exchanger comprising (a) a hollow, cylindrical roller mounted on its longitudinal axis for rotation about said axis; (b) a manifold positioned in the hollow interior of said roller, said manifold comprising (bi) a central pipe which extends axially along the longitudinal axis of said roller, (b2) a plurality of spoke pipes, wherein said spoke pipes are in communication with said central pipe and with the hollow interior of said roller; (c) a supply means for introducing a heat exchange fluid into said central pipe; and (d) a discharge means for removing said heat exchange fluid from the hollow interior of said roller, so that said heat exchange fluid is sequentially introduced to said central pipe, transferred through said central pipe and then through said spoke pipes, so as to exit said spoke pipes and collide against the inside surface of said roller, thereafter turbulently mixing with the entire mass of said heat exchange fluid contained within the substantially full roller, and thereafter withdraw

Abstract: A method for controlling undesired vegetation comprises contacting the vegetation with a herbicidally effective amount of a composition containing the compound of the formula ROOC(CH.sub.2).sub.n COOR' wherein R and R' are independently selected from a C.sub.1 to C.sub.8 alkyl group and n is from 1 to 8.

Abstract: A process of producing compounds containing an acyloxyalkoxy group from an alcohol consists of reacting the alcohol with a formaldehyde donor until a compound of the formula:R--O--CH.sub.2 (OCH.sub.2).sub.X OR (V)is generated, wherein x is between about 1 to about 5 and R is an organic moiety. This product is then reacted with a carboxylic acid anhydride. The resulting product has the formula:R--O--CH.sub.2 O--COR.sup.1wherein R.sup.1 is a C.sub.1 -C.sub.6 alkyl group. The invention further relates to intermediates used in the production of such acyloxyalkoxylated compounds.

Abstract: A heat exchanger comprising (a) a hollow, cylindrical roller mounted on its longitudinal axis for rotation about said axis; (b) a manifold positioned in the hollow interior of said roller, said manifold comprising (b1) a central pipe which extends axially along the longitudinal axis of said roller, (b2) a plurality of spoke pipes, wherein said spoke pipes are in communication with said central pipe and with the hollow interior of said roller; (c) a supply means for introducing a heat exchange fluid into said central pipe; and (d) a discharge means for removing said heat exchange fluid from the hollow interior of said roller, so that said heat exchange fluid is sequentially introduced to said central pipe, transferred through said central pipe and then through said spoke pipes, so as to exit said spoke pipes and collide against the inside surface of said roller, thereafter turbulently mixing with the entire mass of said heat exchange fluid contained within the substantially full roller, and thereafter withdraw

Abstract: A method of transferring heat between a feed material and a heat exchange fluid employs a heat exchanger comprising (a) a hollow, cylindrical roller mounted on its longitudinal axis for rotation about said axis; (b) a manifold positioned in the hollow interior of said roller, said manifold comprising (b1) a central pipe which extends axially along the longitudinal axis of said roller, (b2) a plurality of spoke pipes, wherein said spoke pipes are in communication with said central pipe and with the hollow interior of said roller; (c) a supply means for introducing a heat exchange fluid into said central pipe; and (d) a discharge means for removing said heat exchange fluid from the hollow interior of said roller, so that said heat exchange fluid is sequentially introduced to said central pipe, transferred through said central pipe and then through said spoke pipes, so as to exit said spoke pipes and collide against the inside surface of said roller, thereafter turbulently mixing with the entire mass of said hea

Abstract: A process for isomerizing a chlorofluorocarbon of the formula:CClFYCClFXwherein X and Y are independently selected from chlorine and fluorine provided that X is not --Cl when Y is --Fto the compound of the formula:CCl.sub.2 YCF.sub.2 XThe process comprises contacting the chlorofluorocarbon with an activated aluminum trihalide catalyst. The catalyst is prepared by contacting the chlorofluorocarbon with anhydrous aluminum trichloride in the presence of a metal. The metal is selected from the group consisting of stainless steel, chromium, manganese, molybdenum, tungsten and combinations thereof.

Abstract: A process of isomerizing a chlorofluorocarbon of the formula: ##STR1## wherein X is chlorine or fluorine to the compound of the formula: ##STR2## The process comprises contacting the chlorofluorocarbon with an activated aluminum trichloride catalyst. The catalyst is prepared by contacting the chlorofluorocarbon with anhydrous aluminum trichloride in the presence of a metal. The metal is selected from the group consisting of stainless steel, chromium, manganese, molybdenum, tungsten and combinations thereof.