Patents Assigned to DKFZ Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts
  • Means and methods for treating or preventing brain tumors based on the nuclear receptor tailless (TIx)
    Patent number: 8992923
    Abstract: The present invention relates to the use of an inhibitor of tailless gene expression or tailless protein activity for the preparation of a pharmaceutical composition for treating or preventing the brain tumor in a subject. Preferably an inhibitor of tailless expression is a single or double stranded RNA. An inhibitor of tailless protein activity is preferably an antibody which specifically binds thereto. Finally, the invention includes methods for identifying anti-brain tumor drugs.
    Type: Grant
    Filed: February 22, 2013
    Date of Patent: March 31, 2015
    Assignee: DKFZ Deutsches Krebsforschungszentrum, Stiftung des Oeffentlichen Rechts
    Inventors: Hai-Kun Liu, Guenther Schuetz
  • MEANS AND METHODS FOR TREATING OR PREVENTING BRAIN TUMORS BASED ON THE NUCLEAR RECEPTOR TAILLESS (TIX)
    Publication number: 20130189267
    Abstract: The present invention relates to the use of an inhibitor of tailless gene expression or tailless protein activity for the preparation of a pharmaceutical composition for treating or preventing the brain tumor in a subject. Preferably an inhibitor of tailless expression is a single or double stranded RNA. An inhibitor of tailless protein activity is preferably an antibody which specifically binds thereto. Finally, the invention includes methods for identifying anti-brain tumor drugs.
    Type: Application
    Filed: February 22, 2013
    Publication date: July 25, 2013
    Applicant: DKFZ Deutsches Krebsforschungszentrum, Stiftung Des Oeffentlichen Rechts
    Inventor: DKFZ Deutsches Krebsforschungszentrum, Stiftung Des Oeffentlichen Rechts
  • Means and methods for treating or preventing brain tumors based on the nuclear receptor tailless (Tlx)
    Patent number: 8404657
    Abstract: The present invention relates to the use of an inhibitor of tailless gene expression or tailless protein activity for the preparation of a pharmaceutical composition for treating or preventing the brain tumor in a subject. Preferably an inhibitor of tailless expression is a single or double stranded RNA. An inhibitor of tailless protein activity is preferably an antibody which specifically binds thereto. Finally, the invention includes methods for identifying anti-brain tumor drugs.
    Type: Grant
    Filed: November 18, 2008
    Date of Patent: March 26, 2013
    Assignee: DKFZ Deutsches Krebsforschungszentrum, Stiftung des Oeffentlichen Rechts
    Inventors: Hai-Kun Liu, Günther Schütz
  • Composition comprising an oligonucleotide mixture for improved detection of human papillomavirus genotypes
    Patent number: 8202694
    Abstract: The present invention relates to a composition comprising an oligonucleotide mixture. Moreover, the present invention relates to the use of said oligonucleotide mixture for diagnosing different HPV genotypes in a sample of a subject. Further encompassed is a method for diagnosing different HPV genotypes in a sample of a subject and a kit carrying out said method.
    Type: Grant
    Filed: August 26, 2008
    Date of Patent: June 19, 2012
    Assignee: DKFZ Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts
    Inventors: Markus Schmitt, Tim Waterboer, Michael Pawlita
  • METHOD FOR LUNG CANCER EARLY DETECTION AND PROGNOSIS
    Publication number: 20110183864
    Abstract: The present invention provides method for the prognosis or detection of lung cancer, notably for early detection of lung cancer, as well as a kit and a (micro) array suitable for said method.
    Type: Application
    Filed: July 15, 2009
    Publication date: July 28, 2011
    Applicants: UNIVERSITAET ZU KOELN, DKFZ DEUTSCHES KREBSFORSCHUNGSZENTRUM, STIFTUNG DES OEFFENTLICHEN RECHTS
    Inventors: Thomas Zander, Joachim L. Schultze, Juergen Wolf, Andrea Staratschek-Jox, Svenja Debey-Pascher, Daniela Maisel, Paolo Boffetta, Jakob Linseisen