Patents Assigned to DNA THERAPEUTICS
  • Optimized in vivo delivery system with endosomolytic agents for nucleic acid conjugates
    Patent number: 9428538
    Abstract: The present invention relates to an optimized in vivo delivery system with endosomolytic agents for nucleic acid of therapeutic interest conjugated to molecules facilitating endocytosis, in particular for use in the treatment of cancer.
    Type: Grant
    Filed: October 27, 2015
    Date of Patent: August 30, 2016
    Assignees: DNA THERAPEUTICS, INSTITUT CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Jian-Sheng Sun, Marie Dutreix, Maria Quanz
  • Optimized in vivo delivery system with endosomolytic agents for nucleic acid conjugates
    Patent number: 9205099
    Abstract: The present invention relates to an optimized in vivo delivery system with endosomolytic agents for nucleic acid of therapeutic interest conjugated to molecules facilitating endocytosis, in particular for use in the treatment of cancer.
    Type: Grant
    Filed: June 21, 2011
    Date of Patent: December 8, 2015
    Assignees: DNA THERAPEUTICS, INSTITUT CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Jian-Sheng Sun, Marie Dutreix, Maria Quanz
  • Cancer treatment by combining DNA molecules mimicking double strand breaks with hyperthermia
    Patent number: 9205101
    Abstract: The present invention relates to a method for treating a cancer including a combination of a treatment by a nucleic acid molecule mimicking double strand breaks with hyperthermia.
    Type: Grant
    Filed: May 25, 2012
    Date of Patent: December 8, 2015
    Assignees: INSTITUT CURIE, DNA THERAPEUTICS
    Inventors: Marie Dutreix, Jian-Sheng Sun, Flavien Devun
  • CANCER TREATMENT BY COMBINING DNA MOLECULES MIMICKING DOUBLE STRAND BREAKS WITH HYPERTHERMIA
    Publication number: 20140100266
    Abstract: The present invention relates to a method for treating a cancer including a combination of a treatment by a nucleic acid molecule mimicking double strand breaks with hyperthermia.
    Type: Application
    Filed: May 25, 2012
    Publication date: April 10, 2014
    Applicants: DNA THERAPEUTICS, INSTITUT CURIE
    Inventors: Marie Dutreix, Jian-Sheng Sun, Flavien Devun
  • Optimized In Vivo Delivery System with Endosomolytic Agents for Nucleic Acid Conjugates
    Publication number: 20130131155
    Abstract: The present invention relates to an optimized in vivo delivery system with endosomolytic agents for nucleic acid of therapeutic interest conjugated to molecules facilitating endocytosis, in particular for use in the treatment of cancer.
    Type: Application
    Filed: June 21, 2011
    Publication date: May 23, 2013
    Applicants: DNA THERAPEUTICS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT CURIE
    Inventors: Jian-Sheng Sun, Marie Dutreix, Maria Quanz