Patents Assigned to DNAtrix
  • ARMED REPLICATION-COMPETENT ONCOLYTIC ADENOVIRUSES
    Publication number: 20180169271
    Abstract: Disclosed are replication-competent oncolytic adenoviruses, comprising chimeric human/mouse CD40 ligands. The oncolytic adenoviruses may be replication competent. The chimeric human/mouse CD40 ligand may be MEM40. Also disclosed are methods comprising administering a replication competent oncolytic adenovirus armed with at least one chimeric human/mouse CD40 ligand, for example MEM40, to a patient suffering from a cancer.
    Type: Application
    Filed: December 19, 2017
    Publication date: June 21, 2018
    Applicants: Memgen, LLC, DNAtrix
    Inventors: Mark J. Cantwell, Winnie M. Chan, Brett Ewald, Joan M. Robbins