Patents Assigned to Dolorgiet Beteiligungs GmbH
  • Patent number: 5173304
    Abstract: The agents for the treatment of conditions of severe pain, and especially of tumor pain and post-operative pain, consist of soft gelatin capsules containing from about 30 to about 50 parts by weight of ibuprofen and from about 1.5 to about 4 parts by weight of codeine and/or physiologically compatible salts thereof, partially dissolved and partially suspended in about 68.5 to about 46 parts by weight of polyoxyethylene-polyoxypropylene-diol or in a mixture comprising about 30 to about 76 parts by weight of polyoxyethylene-polyoxypropylene- diol or polyethylene-glycol or polypropyleneglycol and from about 7 to about 40 parts by weight of a physiologically compatible surfactant.
    Type: Grant
    Filed: August 14, 1990
    Date of Patent: December 22, 1992
    Assignee: Dolorgiet Beteiligungs GmbH
    Inventors: Manfred Lohner, Klaus Posselt, Ute Vogtle-Junkert, Hans H. Wagener
  • Patent number: 4849418
    Abstract: Transdermally absorbable water-containing preparations of therapeutically active arylpropionic acid derivatives comprises 1 to 15% by weight of such active ingredient, from 10 to 40% by weight of polyoxyethylene polyoxypropylene copolymers, from 10 to 50% by weight of one or more physiologically acceptable organic solvents, optionally up to 1% by weight of preservatives, colorants and/or perfumes, and at least 10% by weight of water. From polyoxyethylene polyoxypropylene copolymers having a relative molecular weight of more than 6,000 there may also be prepared gels, if certain ratios of amounts are chosen.
    Type: Grant
    Filed: November 16, 1987
    Date of Patent: July 18, 1989
    Assignee: Dolorgiet Beteiligungs-GmbH
    Inventors: Manfred Lohner, Hans H. Wagener
  • Patent number: 4690823
    Abstract: Soft gelatin capsules containing a solution of from 15 to 30 parts by weight of ibuprofen in from 70 to 85 parts by weight of polyoxyethylene-polyoxypropylene polymer or in a mixture of from 30 to 76 parts by weight of polyalkylene glycol and from 7 to 40 parts by weight of a surfactant have a very rapid and high bio-availability of the active ingredient. The active ingredient is not re-precipitated therefrom by aqueous media such as artificial gastric juice.
    Type: Grant
    Filed: March 8, 1985
    Date of Patent: September 1, 1987
    Assignee: Dolorgiet Beteiligungs-GmbH
    Inventors: Manfred Lohner, Klaus Posselt
  • Patent number: 4371545
    Abstract: The present invention relates to new isopropyl amine compounds and processes for preparing the same. This invention also relates to pharmaceutical compositions containing said isopropyl amine compounds.The new isopropyl amine compounds correspond to the following general formula: ##STR1## wherein R represents a nitrophenyl radical, which may be substituted one or more times by halogen, preferably chloride, and/or by lower straignt- or branched-chain alkyl radicals containing from 1 to 4 carbon atoms an/or by alkoxy radicals containing from 1 to 3 carbon atoms and salts thereof with physiologically compatible acids.
    Type: Grant
    Filed: March 17, 1981
    Date of Patent: February 1, 1983
    Assignee: Dolorgiet Beteiligungs GmbH
    Inventors: Wilhelm Kunz, Klaus Gruber