Patents Assigned to DOMPE PHA.MA S.P.A.
  • Human Anti-Folate Receptor Alpha Antibodies and Antibody Fragments for the Radioimmunotherapy of Ovarian Carcinoma
    Publication number: 20100055034
    Abstract: Antibody or fragment thereof, which specifically binds to folate receptor-alpha (FR?), wherein said antibody or fragment thereof comprises a light chain whose variable region comprises at least one of the following amino acid sequences: RASESVSFLGINLIH, (SEQ ID NO: 3) QASNKDT, (SEQ ID NO: 4) LQSKNFPPYT, (SEQ ID NO: 5) and wherein the constant region of said light chain is a kappa constant region.
    Type: Application
    Filed: September 12, 2007
    Publication date: March 4, 2010
    Applicants: DOMPE PHA.MA S.P.A., Istituto Nazionale per lo Studio e la Cura dei Tumori
    Inventors: Franck Martin, Margherita Cattozzo, Giovanni Maurizi, Vito Di Cioccio, Mariangela Figini, Silvana Canevari