Abstract: The object of the present invention is to provide an improved process for preparing benzodiazepine-3-alkyl carboxylate of formula(I) and its pharmaceutically acceptable salts and esters. ##STR1## wherein R.sup.1 is methyl, ethyl or isopropyl;R.sup.2 and R.sup.3 are each independently hydrogen or C.sub.1 -C.sub.6 lower alkyl;R.sup.4 is hydrogen, halogen or trifluoromethyl;carbon atom denoted as c has the S-- or R, S-- configuration.
Type:
Grant
Filed:
September 8, 1997
Date of Patent:
October 6, 1998
Assignee:
Dong Kook Pharmaceutical Company, Inc.
Inventors:
Yong Hae Kim, Jin Kyu Park, Kwon Kim, Hee Sock Park