Abstract: The object of this invention is to provide novel buprenorphine analgesic analogues represented by following formula(I) and their non-toxic pharmaceutically acceptable salts. ##STR1## wherein R.sub.1 is hydrogen atom, methyl, ethyl, cyclopropyl or cyclobutyl; andR.sub.2 is cyclopropyl or cyclobutyl.
Type:
Grant
Filed:
May 21, 1997
Date of Patent:
December 15, 1998
Assignee:
Dong Kook Pharmaceutical Company, Ltd.
Inventors:
Yong Hae Kim, Jin Kyu Park, Kwon Kim, Hee Sock Park