Patents Assigned to Dongguan APAC Biotechnology Co., Ltd.
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Patent number: 10563185Abstract: A beta-glucosidase having improved enzymatic activity is disclosed. The amino acid sequence of the beta-glucosidase is a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of tyrosine at position 286 with phenylalanine, or a substitution of asparagine at position 639 with glutamate.Type: GrantFiled: March 25, 2019Date of Patent: February 18, 2020Assignee: DONGGUAN APAC BIOTECHNOLOGY CO., LTD.Inventors: Hui-Lin Lai, Ya-Shan Cheng, Tzu-Hui Wu, Cheng-Yen Lin, Ting-Yung Huang, I-Hsuan Lin, Cheng-Bin Zheng
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Patent number: 10385346Abstract: A xylosidase having improved enzymatic activity is disclosed. The amino acid sequence of the xylosidase is a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of phenylalanine at position 35 with glutamate, and/or a substitution of glutamine at position 41 with histidine.Type: GrantFiled: October 11, 2018Date of Patent: August 20, 2019Assignee: DONGGUAN APAC BIOTECHNOLOGY CO., LTD.Inventors: Ya-Shan Cheng, Tzu-Hui Wu, Cheng-Yen Lin, Hui-Lin Lai, Cheng-Bin Zheng, Ting-Yung Huang, I-Hsuan Lin, Jian-Wen Huang, Chun-Chi Chen, Rey-Ting Guo
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Patent number: 10233430Abstract: A glucose oxidase having improved thermostability is disclosed. The amino acid sequence of the glucose oxidase is a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of glutamate at position 129 with proline, and/or a substitution of glutamine at position 243 with valine.Type: GrantFiled: September 13, 2018Date of Patent: March 19, 2019Assignee: DONGGUAN APAC BIOTECHNOLOGY CO.,LTD.Inventors: Ya-Shan Cheng, Tzu-Hui Wu, Cheng-Yen Lin, Hui-Lin Lai, Cheng-Bin Zheng, Ting-Yung Huang, I-Hsuan Lin, Jian-Wen Huang, Chun-Chi Chen, Rey-Ting Guo
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Patent number: 10011822Abstract: A phytase having improved thermostability is disclosed. The phytase has a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is one of mutations A to D. The mutation A is to substitute amino acids at positions 143 and 262 with cysteine, the mutation B is to substitute amino acids at positions 259 and 312 with cysteine, the mutation C is to substitute amino acids at positions 205 and 257 with cysteine, and the mutation D is to substitute amino acids at positions 264 and 309 with cysteine.Type: GrantFiled: February 17, 2017Date of Patent: July 3, 2018Assignee: DONGGUAN APAC BIOTECHNOLOGY CO., LTD.Inventors: Tzu-Hui Wu, Ya-Shan Cheng, Hui-Lin Lai, Cheng-Yen Lin, Tsung-Yu Ko, Jian-Wen Huang, Chun-Chi Chen, Rey-Ting Guo
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Patent number: 9944915Abstract: A cellulase having improved thermostability is disclosed. The cellulase comprises a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is adding a cysteine in N terminal and adding a glycine and a cysteine or adding a proline and a cysteine in C terminal.Type: GrantFiled: December 16, 2016Date of Patent: April 17, 2018Assignee: DONGGUAN APAC BIOTECHNOLOGY CO., LTD.Inventors: Rey-Ting Guo, Ya-Shan Cheng, Jian-Wen Huang, Tzu-Hui Wu, Hui-Lin Lai, Cheng-Yen Lin, Tsung-Yu Ko
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Patent number: 9809807Abstract: A cellulase having improved enzymatic activity is disclosed. The cellulase comprises a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of Tyrosine at position 161 with Histidine.Type: GrantFiled: July 17, 2017Date of Patent: November 7, 2017Assignee: DONGGUAN APAC BIOTECHNOLOGY CO., LTD.Inventors: Rey-Ting Guo, Chun-Chi Chen, Ya-Shan Cheng, Jian-Wen Huang, Tzu-Hui Wu, Hui-Lin Lai, Cheng-Yen Lin, Tsung-Yu Ko
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Patent number: 9650625Abstract: A pectinase having improved thermostability is disclosed. The pectinase has a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of serine at position 181 with phenylalanine, methionine or leucine.Type: GrantFiled: October 26, 2016Date of Patent: May 16, 2017Assignee: DONGGUAN APAC BIOTECHNOLOGY CO., LTD.Inventors: Rey-Ting Guo, Ya-Shan Cheng, Jian-Wen Huang, Tzu-Hui Wu, Hui-Lin Lai, Cheng-Yen Lin, Tsung-Yu Ko
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Patent number: 9194010Abstract: A phytase having improved enzymatic activity is disclosed. The phytase has a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of Valine at position 90 with Threonine. Alternatively, the phytase has a modified amino acid sequence of SEQ ID NO: 6, wherein the modification is a substitution of Asparagine at position 204 with Alanine or a substitution of Serine at position 206 with Alanine.Type: GrantFiled: July 22, 2014Date of Patent: November 24, 2015Assignee: DONGGUAN APAC BIOTECHNOLOGY CO., LTD.Inventors: Rey-Ting Guo, Tzu-Hui Wu, Ya-Shan Cheng, Jian-Wen Huang, Hui-Lin Lai, Cheng-Yen Lin, Ting-Yung Huang
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Patent number: 8999695Abstract: A ?-mannanase having increased production yield and enzymatic activity is disclosed. The ?-mannanase has a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of Tyrosine at position 25 with Histidine.Type: GrantFiled: August 18, 2014Date of Patent: April 7, 2015Assignee: DongGuan APAC Biotechnology Co., Ltd.Inventors: Rey-Ting Guo, Jian-Wen Huang, Ya-Shan Cheng, Tzu-Hui Wu, Hui-Lin Lai, Cheng-Yen Lin, Ting-Yung Huang
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Publication number: 20140315273Abstract: A ?-mannanase having increased enzymaic activity is disclosed. The ?-mannanase has a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of Tyrosine at position 216 with Tryptophan.Type: ApplicationFiled: September 5, 2013Publication date: October 23, 2014Applicant: Dongguan APAC Biotechnology CO., Ltd.Inventors: Rey-Ting Guo, Jian-Wen Huang, Ya-Shan Cheng, Tzu-Hui Wu, Hui-Lin Lai, Cheng-Yen Lin, Ting-Yung Huang
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Patent number: 8865444Abstract: A ?-mannanase having increased enzymaic activity is disclosed. The ?-mannanase has a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of Tyrosine at position 216 with Tryptophan.Type: GrantFiled: September 5, 2013Date of Patent: October 21, 2014Assignee: Dongguan APAC Biotechnology Co., Ltd.Inventors: Rey-Ting Guo, Jian-Wen Huang, Ya-Shan Cheng, Tzu-Hui Wu, Hui-Lin Lai, Cheng-Yen Lin, Ting-Yung Huang
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Patent number: 8722382Abstract: A xylanase having increased enzymaic activity is disclosed. The xylanase has a modified amino acid sequence of SEQ ID NO: 2, wherein Tryptophan at position 125 is substituted with Phenylalanine and Phenylalanine at position 163 is substituted with Tryptophan.Type: GrantFiled: September 27, 2013Date of Patent: May 13, 2014Assignee: Dongguan APAC Biotechnology Co., Ltd.Inventors: Rey-Ting Guo, Ya-Shan Cheng, Jian-Wen Huang, Tzu-Hui Wu, Hui-Lin Lai, Cheng-Yen Lin, Ting-Yung Huang