Patents Assigned to Dongguan APAC Biotechnology Co., Ltd.
  • Patent number: 10563185
    Abstract: A beta-glucosidase having improved enzymatic activity is disclosed. The amino acid sequence of the beta-glucosidase is a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of tyrosine at position 286 with phenylalanine, or a substitution of asparagine at position 639 with glutamate.
    Type: Grant
    Filed: March 25, 2019
    Date of Patent: February 18, 2020
    Assignee: DONGGUAN APAC BIOTECHNOLOGY CO., LTD.
    Inventors: Hui-Lin Lai, Ya-Shan Cheng, Tzu-Hui Wu, Cheng-Yen Lin, Ting-Yung Huang, I-Hsuan Lin, Cheng-Bin Zheng
  • Patent number: 10385346
    Abstract: A xylosidase having improved enzymatic activity is disclosed. The amino acid sequence of the xylosidase is a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of phenylalanine at position 35 with glutamate, and/or a substitution of glutamine at position 41 with histidine.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: August 20, 2019
    Assignee: DONGGUAN APAC BIOTECHNOLOGY CO., LTD.
    Inventors: Ya-Shan Cheng, Tzu-Hui Wu, Cheng-Yen Lin, Hui-Lin Lai, Cheng-Bin Zheng, Ting-Yung Huang, I-Hsuan Lin, Jian-Wen Huang, Chun-Chi Chen, Rey-Ting Guo
  • Patent number: 10233430
    Abstract: A glucose oxidase having improved thermostability is disclosed. The amino acid sequence of the glucose oxidase is a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of glutamate at position 129 with proline, and/or a substitution of glutamine at position 243 with valine.
    Type: Grant
    Filed: September 13, 2018
    Date of Patent: March 19, 2019
    Assignee: DONGGUAN APAC BIOTECHNOLOGY CO.,LTD.
    Inventors: Ya-Shan Cheng, Tzu-Hui Wu, Cheng-Yen Lin, Hui-Lin Lai, Cheng-Bin Zheng, Ting-Yung Huang, I-Hsuan Lin, Jian-Wen Huang, Chun-Chi Chen, Rey-Ting Guo
  • Patent number: 10011822
    Abstract: A phytase having improved thermostability is disclosed. The phytase has a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is one of mutations A to D. The mutation A is to substitute amino acids at positions 143 and 262 with cysteine, the mutation B is to substitute amino acids at positions 259 and 312 with cysteine, the mutation C is to substitute amino acids at positions 205 and 257 with cysteine, and the mutation D is to substitute amino acids at positions 264 and 309 with cysteine.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: July 3, 2018
    Assignee: DONGGUAN APAC BIOTECHNOLOGY CO., LTD.
    Inventors: Tzu-Hui Wu, Ya-Shan Cheng, Hui-Lin Lai, Cheng-Yen Lin, Tsung-Yu Ko, Jian-Wen Huang, Chun-Chi Chen, Rey-Ting Guo
  • Patent number: 9944915
    Abstract: A cellulase having improved thermostability is disclosed. The cellulase comprises a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is adding a cysteine in N terminal and adding a glycine and a cysteine or adding a proline and a cysteine in C terminal.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: April 17, 2018
    Assignee: DONGGUAN APAC BIOTECHNOLOGY CO., LTD.
    Inventors: Rey-Ting Guo, Ya-Shan Cheng, Jian-Wen Huang, Tzu-Hui Wu, Hui-Lin Lai, Cheng-Yen Lin, Tsung-Yu Ko
  • Patent number: 9809807
    Abstract: A cellulase having improved enzymatic activity is disclosed. The cellulase comprises a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of Tyrosine at position 161 with Histidine.
    Type: Grant
    Filed: July 17, 2017
    Date of Patent: November 7, 2017
    Assignee: DONGGUAN APAC BIOTECHNOLOGY CO., LTD.
    Inventors: Rey-Ting Guo, Chun-Chi Chen, Ya-Shan Cheng, Jian-Wen Huang, Tzu-Hui Wu, Hui-Lin Lai, Cheng-Yen Lin, Tsung-Yu Ko
  • Patent number: 9650625
    Abstract: A pectinase having improved thermostability is disclosed. The pectinase has a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of serine at position 181 with phenylalanine, methionine or leucine.
    Type: Grant
    Filed: October 26, 2016
    Date of Patent: May 16, 2017
    Assignee: DONGGUAN APAC BIOTECHNOLOGY CO., LTD.
    Inventors: Rey-Ting Guo, Ya-Shan Cheng, Jian-Wen Huang, Tzu-Hui Wu, Hui-Lin Lai, Cheng-Yen Lin, Tsung-Yu Ko
  • Patent number: 9194010
    Abstract: A phytase having improved enzymatic activity is disclosed. The phytase has a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of Valine at position 90 with Threonine. Alternatively, the phytase has a modified amino acid sequence of SEQ ID NO: 6, wherein the modification is a substitution of Asparagine at position 204 with Alanine or a substitution of Serine at position 206 with Alanine.
    Type: Grant
    Filed: July 22, 2014
    Date of Patent: November 24, 2015
    Assignee: DONGGUAN APAC BIOTECHNOLOGY CO., LTD.
    Inventors: Rey-Ting Guo, Tzu-Hui Wu, Ya-Shan Cheng, Jian-Wen Huang, Hui-Lin Lai, Cheng-Yen Lin, Ting-Yung Huang
  • Patent number: 8999695
    Abstract: A ?-mannanase having increased production yield and enzymatic activity is disclosed. The ?-mannanase has a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of Tyrosine at position 25 with Histidine.
    Type: Grant
    Filed: August 18, 2014
    Date of Patent: April 7, 2015
    Assignee: DongGuan APAC Biotechnology Co., Ltd.
    Inventors: Rey-Ting Guo, Jian-Wen Huang, Ya-Shan Cheng, Tzu-Hui Wu, Hui-Lin Lai, Cheng-Yen Lin, Ting-Yung Huang
  • Publication number: 20140315273
    Abstract: A ?-mannanase having increased enzymaic activity is disclosed. The ?-mannanase has a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of Tyrosine at position 216 with Tryptophan.
    Type: Application
    Filed: September 5, 2013
    Publication date: October 23, 2014
    Applicant: Dongguan APAC Biotechnology CO., Ltd.
    Inventors: Rey-Ting Guo, Jian-Wen Huang, Ya-Shan Cheng, Tzu-Hui Wu, Hui-Lin Lai, Cheng-Yen Lin, Ting-Yung Huang
  • Patent number: 8865444
    Abstract: A ?-mannanase having increased enzymaic activity is disclosed. The ?-mannanase has a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of Tyrosine at position 216 with Tryptophan.
    Type: Grant
    Filed: September 5, 2013
    Date of Patent: October 21, 2014
    Assignee: Dongguan APAC Biotechnology Co., Ltd.
    Inventors: Rey-Ting Guo, Jian-Wen Huang, Ya-Shan Cheng, Tzu-Hui Wu, Hui-Lin Lai, Cheng-Yen Lin, Ting-Yung Huang
  • Patent number: 8722382
    Abstract: A xylanase having increased enzymaic activity is disclosed. The xylanase has a modified amino acid sequence of SEQ ID NO: 2, wherein Tryptophan at position 125 is substituted with Phenylalanine and Phenylalanine at position 163 is substituted with Tryptophan.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: May 13, 2014
    Assignee: Dongguan APAC Biotechnology Co., Ltd.
    Inventors: Rey-Ting Guo, Ya-Shan Cheng, Jian-Wen Huang, Tzu-Hui Wu, Hui-Lin Lai, Cheng-Yen Lin, Ting-Yung Huang