Abstract: A method for delivering at least an active principal A to a human or animal, by administering, in vivo, an active compound of general formula A?V?C?, that is capable of restoring at least the entity A by cleavage, in vivo, of the corresponding attachments between A? and V?, wherein V is a biogenic vectorization compound of general formula X-R-Y, where R represents an aliphatic, cyclic or alicyclic, saturated or unsaturated hydrocarbon chain of 2 to 10 carbon atoms, and X and Y are each a free acid, amine or alcohol function; and A and C are two respectively different active principles, one of which has a chemical function complementary to the function of X, capable of reacting with the latter to give an ionic A? - - - V? or covalent A?—V? attachment that can be cleaved in vivo, and the other of which has a chemical function complementary to the function of Y, capable of reacting with the latter to give an ionic V? - - - C? or covalent V?—C? attachment.

Abstract: A medicinal combination for the treatment of diabetes, in particular of type 2 diabetes, combining a biguanide, in particular an N-dimethylbiguanide, as a first medicament, and an agent for transporting the said biguanide, as a second medicament, said combination comprising: e [sic] a therapeutically active quantity of the biguanide f [sic] and a quantity of transporting agent, previously determined to potentiate the therapeutic activity of the biguanide according to (a).

Abstract: The present invention relates to a compound of formula III, method of making the same and its use in the treatment of diabetes.