Abstract: This invention relates to stable liquid formulations of the nitrification inhibitor nitrapyrin comprising polar solvents that are stabilized with small amounts of compounds which help to reduce the tendency of polar solutions of nitrapyrin to corrode metal surfaces. Many of the formulations disclosed herein exhibit useful physical, chemical, and bioactive properties including reduced levels of corrosion when in contact with ferrous metals.
Type:
Grant
Filed:
May 11, 2016
Date of Patent:
January 8, 2019
Assignee:
Dow Agrosciences, LLC
Inventors:
Hiteshkumar Dave, Lei Liu, Alex Williams, Rajesh Goyal, Nicholas Fradette, Chloe Moreau, Samantha Armisen, Kevin Mayer
Abstract: This disclosure concerns compositions and methods for identifying the phytophthora resistant phenotype in soybean. In some embodiments, the disclosure concerns methods for performing marker-assisted breeding and selection of plants carrying one or more determinants of phytophthora resistance in soybean. In some embodiments, the disclosure concerns methods for detecting phytophthora resistance in soybean via the use of an amplification reaction.
Type:
Grant
Filed:
March 11, 2014
Date of Patent:
January 8, 2019
Assignee:
Dow AgroSciences LLC
Inventors:
Yonghe Bai, Fang Lu, Tyler Mansfield, Jenelle Meyer, Robert E. Moore, Bradley Hedges, William M. Campbell, Julu Manandhar, Jan E. Backlund, David H. Meyer, Siva P. Kumpatla, Raghav Ram
Abstract: A safened herbicidal composition for use in rice comprising a herbicidally effective amount of (a) a compound of formula (I): or an agriculturally acceptable salt or ester thereof and (b) a safener or a compatible herbicide capable of safening such as a chemical from the quinolinyloxyacetate family of chemicals, dicyclonon, daimuron, dimepiperate, fenclorim, furilazole, halosulfuron, isoxadifen-ethyl, mefenpyr-diethyl, naphthalic anhydride (NA), or agriculturally acceptable salts, esters, or mixtures thereof, for use in direct-seeded, water-seeded or transplanted rice.
Abstract: The subject invention provides novel plants that are not only resistant to 2,4-D and other phenoxy auxin herbicides, but also to aryloxyphenoxypropionate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention alone or “stacked” together with another herbicide resistance gene, preferably a glyphosate resistance gene, so as to provide broader and more robust weed control, increased treatment flexibility, and improved herbicide resistance management options. More specifically, preferred enzymes and genes for use according to the subject invention are referred to herein as AAD (aryloxyalkanoate dioxygenase) genes and proteins. No ?-ketoglutarate-dependent dioxygenase enzyme has previously been reported to have the ability to degrade herbicides of different chemical classes and modes of action.
Type:
Grant
Filed:
August 7, 2015
Date of Patent:
January 8, 2019
Assignee:
Dow AgroSciences LLC
Inventors:
Terry Wright, Justin Lira, Donald Merlo, Nicole Arnold
Abstract: A fungicidal composition containing a fungicidally effective amount of (a) the compound of Formula I, (3S,6S,7R,8R)-8-benzyl-3-(3-((isobutyryloxy)methoxy)-4-methoxypicolinamido)-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl isobutyrate, and (b) fluxapyroxad, provides synergistic control of selected fungi.
Type:
Grant
Filed:
December 27, 2013
Date of Patent:
January 8, 2019
Assignee:
Dow AgroSciences LLC
Inventors:
David G. Ouimette, J. Todd Mathieson, Gregory M. Kemmitt
Abstract: The invention relates to picolinamides of Formula I and their use as fungicides.
Type:
Grant
Filed:
December 21, 2015
Date of Patent:
January 8, 2019
Assignee:
Dow AgroSciences LLC
Inventors:
Chenglin Yao, Kevin G. Meyer, Yu Lu, Brian A. Loy, David M. Jones, Ronald J. Heemstra, Jeffrey B. Epp, Johnathan E. DeLorbe, Kyle A. DeKorver, John F. Daeuble, Sr.
Abstract: This disclosure concerns compositions and methods for promoting transcription of a nucleotide sequence in a plant or plant cell, employing a promoter from a Panicum virgatum (Pavir.Cb02009) egg cell gene. Some embodiments relate to a promoter from a Panicum virgatum (Pavir.Cb02009) egg cell gene that functions in plants to promote transcription of operably linked nucleotide sequences. Other embodiments relate to a 3? UTR from a Panicum virgatum (Pavir.Cb02009) egg cell gene that functions in plants to promote transcription of operably linked nucleotide sequences.
Type:
Application
Filed:
September 8, 2017
Publication date:
January 3, 2019
Applicant:
Dow AgroSciences LLC
Inventors:
Sandeep Kumar, Pierluigi Barone, Daren Hemingway, Emily Etchison, Andrew Asberry, Heather Pence, Andrew J. Bowling
Abstract: This document discloses molecules having the following formula (“Formula One”): and processes related thereto.
Type:
Grant
Filed:
March 16, 2017
Date of Patent:
January 1, 2019
Assignee:
Dow AgroSciences LLC
Inventors:
Noormohamed M. Niyaz, Negar Garizi, Yu Zhang, Tony K. Trullinger, Ricky Hunter, Ann M. Buysse, Asako Kubota, Paul R. LePlae, Jr., Daniel I. Knueppel, Christian T. Lowe, Dan Pernich, David A. Demeter, Timothy C. Johnson
Abstract: The instant invention describes compounds of Formula I having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
Type:
Grant
Filed:
March 7, 2018
Date of Patent:
January 1, 2019
Assignee:
Dow AgroSciences LLC
Inventors:
Michael R. Loso, Gary D. Gustafson, Asako Kubota, Maurice C. Yap, Zachary A. Buchan, Kimberly M. Steward, Michael T. Sullenberger, William J. Hoekstra, Christopher M. Yates
Abstract: The subject invention provides novel plants that are not only resistant to 2,4-D, but also to pyridyloxyacetate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention “stacked” together with one or more other herbicide resistance genes. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the development of, and controlling, strains of weeds that are resistant to one or more herbicides such as glyphosate. The preferred enzyme and gene for use according to the subject invention are referred to herein as AAD-12 (AryloxyAlkanoate Dioxygenase). This highly novel discovery is the basis of significant herbicide tolerant crop trait and selectable marker opportunities.
Type:
Grant
Filed:
September 19, 2014
Date of Patent:
January 1, 2019
Assignee:
Dow AgroSciences LLC
Inventors:
Terry R. Wright, Justin M. Lira, Terence Anthony Walsh, Donald Merlo, Jayakumar Pon Samuel, Gaofeng Lin
Abstract: Provided herein is a process for the preparation of 4-((6-(2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile.
Type:
Application
Filed:
November 17, 2016
Publication date:
December 27, 2018
Applicant:
Dow AgroSciences LLC
Inventors:
Qiang Yang, Yan Hao, Sarah Ryan, Gregory Whiteker
Abstract: A method for producing a transgenic plant includes providing a nucleic acid molecule comprising at least two regions of nucleic acid sequence that lack sequence homology with genomic DNA of the plant cell, and at least two zinc finger nuclease recognition sites, wherein the at least two regions of nucleic acid sequence that lack sequence homology with genomic DNA of the plant cell flank the at least two zinc finger nuclease recognition sites. A plant cell or tissue having the nucleic acid molecule stably integrated into the genome of the plant cell is transformed. A plant is regenerated from the plant cell. Transgenic plants are produced by the method. Seeds are produced by the transgenic plants.
Type:
Grant
Filed:
August 12, 2014
Date of Patent:
December 25, 2018
Assignee:
Dow AgroSciences LLC
Inventors:
W. Michael Ainley, Ryan C. Blue, Michael G. Murray, David Richard Corbin, Rebecca Ruth Miles, Steven R. Webb
Abstract: Disclosed herein are methods of controlling a broadleaf volunteer crop, comprising applying to the broadleaf volunteer crop, an area adjacent the broadleaf volunteer crop, or to soil or water to prevent the emergence or growth of the broadleaf volunteer crop, a herbicidally effective amount of a 6-arylpicoline carboxylic acid, a 2-arylpyrimidine carboxylic acid, or a salt or ester thereof, wherein the broadleaf volunteer crop is genetically modified soybean.
Type:
Grant
Filed:
February 26, 2014
Date of Patent:
December 18, 2018
Assignee:
Dow AgroSciences LLC
Inventors:
Paul Richard Schmitzer, Kent William Davies, Monte Ray Weimer
Abstract: Provided herein is a process for the preparation of 4-((6-(2-(2,4-difluorophenyl)-1,1-difiuoro-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile.
Abstract: A process for the alkylation of picolinamides with substituted chloroacylals to produce a structure of Formula (III), wherein the reaction is performed in the presence of a phase-transfer catalyst and an inorganic halide co-catalyst.
Type:
Grant
Filed:
October 3, 2016
Date of Patent:
December 4, 2018
Assignee:
Dow AgroSciences LLC
Inventors:
Matthew J. Jansma, Timothy J. Adaway, Michael Lee Trippeer
Abstract: Improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalkyl and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates and arylalkyl and alkyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates, are described herein. The improved methods include a direct Suzuki coupling step, which eliminates the protection/de-protection steps in the current chemical process, and therefore eliminates or reduces various raw materials, equipment and cycle time as well as modification of other process conditions including use of crude AP, use of ABA-diMe, and varying pH, catalyst concentration, solvent composition, and/or workup procedures. This includes synthesis of 2-aryl-6-aminopyrimidine-4-carboxylates.
Type:
Application
Filed:
July 26, 2018
Publication date:
November 22, 2018
Applicant:
Dow AgroSciences LLC
Inventors:
Jason S. Fisk, Xiaoyong Li, Mark Muehlfeld, Robert S. Bauman, Jooossian Oppenheimer, Siyu Tu, Mark A. Nitz, Reetam Chakrabarti, Shawn D. Feist, James W. Ringer, Ronald B. Leng
Abstract: Improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalkyl and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates and arylalkyl and alkyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates, are described herein. The improved methods include a direct Suzuki coupling step, which eliminates the protection/de-protection steps in the current chemical process, and therefore eliminates or reduces various raw materials, equipment and cycle time as well as modification of other process conditions including use of crude AP, use of ABA-diMe, and varying pH, catalyst concentration, solvent composition, and/or workup procedures. This includes synthesis of 2-aryl-6-aminopyrimidine-4-carboxylates.
Type:
Application
Filed:
July 26, 2018
Publication date:
November 22, 2018
Applicant:
Dow AgroSciences LLC
Inventors:
Jason S. F, Xiaoyong Li, Mark Muehlfeld, Robert S. Bauman, Jossian Oppenheimer, Siyu Tu, Mark A. Nitz, Reetam Chakrabarti, Shawn D. Feist, James W. Ringer, Ronald B. Leng
Abstract: A fungicidal 4-methoxy-3-acetyloxypicolinamide may be conveniently prepared in processes that include the coupling together of 4-methoxy-3-acetyloxypicolinic acid or 4-methoxy-3-hydroxypicolinic acid with a key 2-aminopropanoate ester derived from a 1,1-bis(4-fluorophenyl)propane-1,2-diol.
Type:
Application
Filed:
July 16, 2018
Publication date:
November 8, 2018
Applicant:
Dow AgroSciences LLC
Inventors:
Gregory T. Whiteker, Nakyen Choy, Peter Borromeo, Nicholas R. Babij, Gary Roth, Patrick S. Hanley, Matthias S. Ober, Tina Staton, Daniel I. Knueppel, Grant Von Wald, Nicole Hough