Abstract: Provided are constructs and methods for expressing a transgene in plant cells and/or plant tissues using gene regulatory elements obtained from Brassica napus.
Type:
Grant
Filed:
December 28, 2015
Date of Patent:
August 27, 2019
Assignee:
Dow AgroSciences LLC
Inventors:
Holly Jean Butler, Scott Alan Bevan, Cory M. Larsen, William Moskal, Delkin Orlando Gonzalez
Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of pathogens through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in pathogens. The disclosure also concerns methods for applying dsRNA through formulations and/or transgenic plants that express nucleic acid molecules useful for the control of pathogens, and the plant cells and plants obtained thereby.
Type:
Grant
Filed:
November 1, 2017
Date of Patent:
August 27, 2019
Assignee:
Dow AgroSciences LLC
Inventors:
Javier A. Delgado, Justin M. Lira, Chaoxian Geng, Meghan L. Frey
Abstract: Compositions and methods include genetically encoding and expressing a novel delta-9 desaturase in plant cells. In some embodiments, methods of expressing nucleic acids in a plant cell to take advantage of the delta-9 desaturase enzyme's activity, such that the percent composition of saturated fatty acids in plant seeds is decreased and there is a concomitant increase in ?9 fatty acids. In other embodiments, amino acid sequences have delta-9 desaturase activity. Methods can involve expression of delta-9 desaturase in plant cells, plant materials, and whole plants for the purpose of increasing the amount of mono unsaturated fatty acids in whole plants, plant seeds, and plant materials, for example, seeds.
Type:
Grant
Filed:
January 4, 2017
Date of Patent:
August 6, 2019
Assignee:
Dow AgroSciences LLC
Inventors:
Daniel J. Gachotte, Ann Owens Merlo, Mark A. Thompson, Terence A. Walsh, Beth Rubin Wilson, Mary Welter
Abstract: A fungicidal 4-methoxy-3-acetyloxypicolinamide may be conveniently prepared in processes that include the coupling together of 4-methoxy-3-acetyloxypicolinic acid or 4-methoxy-3-hydroxypicolinic acid with a key 2-aminopropanoate ester derived from a 1,1-bis(4-fluorophenyl)propane-1,2-diol.
Type:
Grant
Filed:
July 16, 2018
Date of Patent:
July 23, 2019
Assignee:
Dow AgroSciences LLC
Inventors:
Gregory T. Whiteker, Nakyen Choy, Peter Borromeo, Nicholas R. Babij, Gary Roth, Patrick S. Hanley, Matthias S. Ober, Tina Staton, Daniel I. Knueppel, Grant Von Wald, Nicole Hough
Abstract: This disclosure concerns compositions and methods for increasing the expression of a polynucleotide of interest. Some embodiments concern novel transactivation polypeptides and variants thereof that have been identified in plants, and methods of using the same. Particular embodiments concern the use of at least one DNA-binding polypeptide in a fusion protein to target at least one transactivation polypeptide or variant thereof to a specific binding site on a nucleic acid comprising the polynucleotide of interest, such that its expression may be increased.
Type:
Grant
Filed:
February 1, 2013
Date of Patent:
July 16, 2019
Assignee:
Dow AgroSciences LLC
Inventors:
Joseph Petolino, Jianquan Li, Steven L Evans, Ryan C Blue
Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran and hemipteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran and hemipteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran and hemipteran pests, and the plant cells and plants obtained thereby.
Type:
Grant
Filed:
October 4, 2016
Date of Patent:
July 9, 2019
Assignee:
Dow AgroSciences LLC
Inventors:
Kenneth E. Narva, Elane Fishilevich, Murugesan Rangasamy, Meghan L. Frey, Wendy Lo, Sarah E. Worden, Premchand Gandra
Abstract: Methods for controlling aquatic weeds using halauxifen or florpyrauxifen or agriculturally acceptable esters or salts thereof in combination with one or more of diquat dibromide, copper salts, endothal, or fluridone, or agriculturally acceptable salts or esters thereof, are described. The herbicidal compositions described allow for effective control and/or selectivity when treating a body of water, to control target aquatic weed populations, such as alligatorweed, yellow nutsedge, barnyardgrass, early watergrass, Echinochloa species, saramollagrass, Chinese sprangletop, hydrilla, Eurasian watermilfoil and/or curlyleaf pondweed.
Abstract: The present disclosure provides methods for detecting and identifying plant events that contain precision targeted genomic loci, and plants and plant cells comprising such targeted genomic loci. The method can be deployed as a high throughput process utilized for screening the intactness or disruption of a targeted genomic loci and optionally for detecting a donor DNA polynucleotide insertion at the targeted genomic loci. The methods are readily applicable for the identification of plant events produced via a targeting method which results from the use of a site specific nuclease.
Type:
Grant
Filed:
August 29, 2016
Date of Patent:
July 9, 2019
Assignee:
Dow AgroSciences LLC
Inventors:
Lakshmi Sastry-Dent, Matthew A. Simpson, Zehui Cao, Wei Chen, Ning Zhou, Steven R. Webb
Abstract: The present disclosure relates to engineered zinc finger proteins that target 5-enolpyruvyl shikimate-3-phosphate synthase (EPSPS) genes in plants and methods of using such zinc finger proteins in modulating gene expression, gene inactivation, and targeted gene modification. In particular, the disclosure pertains to zinc finger nucleases for targeted cleavage and alteration of EPSPS genes.
Type:
Grant
Filed:
November 11, 2014
Date of Patent:
July 9, 2019
Assignees:
Dow AgroSciences LLC, Sangamo Therapeutics, Inc.
Inventors:
Manju Gupta, Asha M. Palta, Stephen Novak, Fyodor Urnov, Sunita Gopalan
Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran and/or hemipteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran and/or hemipteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran and/or hemipteran pests, and the plant cells and plants obtained thereby.
Type:
Grant
Filed:
December 13, 2016
Date of Patent:
June 25, 2019
Assignee:
Dow AgroSciences LLC
Inventors:
Kenneth E. Narva, Elane Fishilevich, Murugesan Rangasamy, Meghan L. Frey, Wendy Lo, Sarah E. Worden, Premchand Gandra
Abstract: This invention relates in part to plant breeding and herbicide tolerant plants. This invention includes a novel aad-1 transformation event in corn plants comprising a polynucleotide sequence, as described herein, inserted into a specific site within the genome of a corn cell. In some embodiments, said event/polynucleotide sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. Additionally, the subject invention provides assays for detecting the presence of the subject event in a sample (of corn grain, for example). The assays can be based on the DNA sequence of the recombinant construct, inserted into the corn genome, and on the genomic sequences flanking the insertion site. Kits and conditions useful in conducting the assays are also provided.
Type:
Grant
Filed:
January 6, 2016
Date of Patent:
June 18, 2019
Assignee:
Dow AgroSciences LLC
Inventors:
Yunxing Cory Cui, Jill Bryan, Donald Maum, Greg Gilles, Terry Wright, Jennifer Hamilton, Nicole Arnold, Nathan VanOpdorp, Tina Kaiser, Ning Zhou
Abstract: The present disclosure describes a method of coupling a first compound to a second compound, the method comprising: providing the first compound having a fluorosulfonate substituent; providing the second compound comprising an amine; and reacting the first compound and the second compound in a reaction mixture, the reaction mixture including a catalyst having at least one group 10 atom, the reaction mixture under conditions effective to couple the first compound to the second compound. The present disclosure further describes a one-pot method for coupling a first compound to a second compound.
Type:
Application
Filed:
February 8, 2019
Publication date:
June 13, 2019
Applicant:
Dow AgroSciences LLC
Inventors:
Patrick S. Hanley, Thomas P. Clark, Matthias S. Ober, William J. Kruper
Abstract: The present application provides processes for making pesticidal compounds and compounds useful both as pesticides and in the making of pesticidal compounds.
Type:
Grant
Filed:
May 8, 2018
Date of Patent:
June 11, 2019
Assignee:
Dow AgroSciences LLC
Inventors:
Qiang Yang, Beth Lorsbach, Gregory Whiteker, Gary Roth, Carl DeAmicis, Thomas Clark, Kaitlyn Gray, Belgin Canturk, Elisabeth J. Kane, Yu Zhang, Joseck M. Muhuhi
Abstract: This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions containing such molecules, and processes of using such pesticidal compositions against such pests. These pesticidal compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula (“Formula One”).
Type:
Application
Filed:
January 18, 2019
Publication date:
June 6, 2019
Applicant:
Dow AgroSciences LLC
Inventors:
Ronald J. Heemstra, Ronald Ross, JR., Timothy P. Martin, Nicolaas Vermeulen, John F. Daeuble, SR., Joseph D. Eckelbarger, Alex Nolan, Kaitlyn Gray, David A. Demeter, Ricky Hunter, Tony K. Trullinger
Abstract: This disclosure concerns compositions and methods for promoting transcription of a nucleotide sequence in a plant or plant cell, employing a Zea mays GRMZM2G144030 promoter. Some embodiments relate to a Zea mays GRMZM2G144030 promoter that functions in plants to promote transcription of operably linked nucleotide sequences. Other embodiments relate to a Zea mays GRMZM2G144030 3?UTR that functions in plants to terminate transcription of operably linked nucleotide sequences.
Abstract: This disclosure concerns compositions and methods for promoting transcription of a nucleotide sequence in a plant or plant cell, employing a promoter from a Zea mays KN1 gene. Some embodiments relate to a promoter from a Zea mays KN1 gene that functions in plants to promote transcription of operably linked nucleotide sequences.
Type:
Application
Filed:
February 11, 2019
Publication date:
May 30, 2019
Applicant:
Dow AgroSciences LLC
Inventors:
John Davies, David Mann, James Patrick Connell, William T. Beeson, IV
Abstract: Provided herein are 2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-substituted-pyridin-2-yl)-3-(1H-tetrazol-1-yl)propan-2-ols and 1-(2,4-difluorophenyl)-2,2-difluoro-2-(5-substituted-pyridin-2-yl)ethanones and processes for their preparation.
Type:
Grant
Filed:
February 1, 2018
Date of Patent:
May 28, 2019
Assignee:
Dow Agrosciences, LLC
Inventors:
William J. Hoekstra, Nakyen Choy, Carl DeAmicis, Daniel Knueppel, Jim Renga, Michael T. Sullenberger, Gregory Whiteker, Yuanming Zhu, Gary D. Gustafson
Abstract: This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions containing such molecules, and processes of using such pesticidal compositions against such pests. These pesticidal compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula (“Formula One”).
Type:
Application
Filed:
January 18, 2019
Publication date:
May 23, 2019
Applicant:
Dow AgroSciences LLC
Inventors:
Ronald J. Heemstra, Ronald Ross, JR., Timothy P. Martin, Nicolaas Vermeulen, John F. Daeuble, SR., Joseph D. Eckelbarger, Alex Nolan, Kaitlyn Gray, David A. Demeter, Ricky Hunter, Tony K. Trullinger