Abstract: The present invention relates to a drop-forming, storage stable, multiphase, ophthalmic composition comprising at least one liquid aqueous phase and at least one liquid hydrophobic phase, characterized in that it is emulsifier-free as well as buffer-free and comprises hyaluronic acid and/or hyaluronate.
Type:
Grant
Filed:
April 12, 2017
Date of Patent:
August 16, 2022
Assignee:
DR. GERHARD MANN CHEM.-PHARM. FABRIK GMBH
Abstract: The invention concerns a method for producing a sterile prednisolone gel. The method is characterized in that prednisolone or its pharmaceutically acceptable ester is sterilized and incorporated into a sterile polyacrylate gel, which has been per se conventionally produced, in appropriate amount under aseptic conditions, or else the sterile prednisolone or its pharmaceutically acceptable ester is suspended in a part of the amount of water required for producing the polyacrylate suspension and is then homogenously incorporated into the polyacryate, which is then made into a gel.
Type:
Grant
Filed:
November 27, 1996
Date of Patent:
September 22, 1998
Assignee:
Dr. Gerhard Mann Chem.-Pharm. Fabrik GmbH