Patents Assigned to Dr. L. Zambeletti S.p.A.
  • Biphenylylalkanoic acid derivatives, methods of preparation and pharmaceutical compositions therefrom
    Patent number: 4570013
    Abstract: Novel compounds of formula ##STR1## are described which have antipyretic, analgesic and antiinflammatory activity. R is hydrogen, C.sub.1 -C.sub.3 linear or branched alkyl; R.sub.1 and R.sub.2 are hydrogen, halogen, unsubstituted or esterified hydroxy, alcoxy, and may be the same or different; R.sub.3 is hydrogen, C.sub.1 -C.sub.4 linear or branched aliphatic acyl, unsubstituted or substituted aroyl, alkylaroyl or hetaroyl groups.
    Type: Grant
    Filed: November 6, 1984
    Date of Patent: February 11, 1986
    Assignee: Dr. L. Zambeletti S.p.A.
    Inventors: Mario Bergamaschi, Gian B. Gervasi, Vittorio Vecchietti, Massimo Signorini
  • 2,4-Dioxacyclohexanone derivative
    Patent number: 4358444
    Abstract: 3-(2-Methoxy-phenoxy)-3-methyl-benzo-2,4-dioxacyclohexanone of formula ##STR1## a process for its preparation through reaction among the chloride of acetylsalicylic acid, guaiacole and pyridine; pharmaceutical compositions containing it.
    Type: Grant
    Filed: September 28, 1981
    Date of Patent: November 9, 1982
    Assignee: Dr. L. Zambeletti S.p.A.
    Inventor: Giuseppe Quadro
  • Use of rifamycin SV and its related salts in the treatment of rheumatoid arthritis, and related formulations suited for the purpose
    Patent number: 4312866
    Abstract: The invention concerns new salts of rifamycin SV and a new use of rifamycin SV in the treatment of rheumatoid arthritis and analogous affections, by intra-articular injection of the sodium salt of rifamycin SV or, better, of salts of said anti-biotic with basic aminoacid, e.g. with arginine, lysine or histidine.
    Type: Grant
    Filed: July 7, 1980
    Date of Patent: January 26, 1982
    Assignee: Dr. L. Zambeletti S.p.A.
    Inventors: Innocenzo Caruso, Franco Montrone, Luigi Molteni
  • Tripeptides, their esters and amides, and anti-ulcera activity thereof
    Patent number: 4048305
    Abstract: This invention relates to aseries of tripeptides of the general formula: ##STR1## wherein R = -- H, COCH.sub.3, alkylR.sub.1 = --oh, --nh.sub.2, --nh alkyl (C.sub.1 -C.sub.5) --O alkyl (C.sub.1 -C.sub.5)resulting from condensing of racemic, levorotatory and dextrorotatory phenylalanine and histidine and having an anti-ulcer activity.
    Type: Grant
    Filed: April 8, 1976
    Date of Patent: September 13, 1977
    Assignee: Dr. L. Zambeletti S.p.A.
    Inventors: Luigi Molteni, Gian Piero Vercesi, Eraldo Antonini