Patents Assigned to Dr. Reddy's Laboratories, Limited
  • Tetracycline derivatives as antibacterial agents
    Patent number: 7939513
    Abstract: In accordance with one aspect, the present invention provides a compound of general formula (I), its stereoisomers thereof and/or its pharmaceutically acceptable salts thereof, which have antibacterial activity; with methods of treating infectious diseases in warm blooded animals employing these new compounds. wherein R1 is selected from optionally substituted alkyl.
    Type: Grant
    Filed: September 8, 2008
    Date of Patent: May 10, 2011
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: Mohamed Takhi, Natesan Selvakumar, Sreenivas Kandepu, Gavara Govinda Rajulu, Javed Iqbal
  • Bisphospholanes for use as catalysts in asymmetric reactions
    Patent number: 7935841
    Abstract: The invention concerns an enantiomerically enriched compound of formula (1) or the opposite enantiomer thereof wherein each of Ar1—Ar4 represent the same or different aromatic groups of up to 20 carbon atoms and the bridging group X is the formula (5) in which * denotes points of attachment to phosphorus atoms and methods of making thereof.
    Type: Grant
    Filed: April 18, 2007
    Date of Patent: May 3, 2011
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: Philip M. Jackson, Ian Campbell Lennon, Martin E. Fox
  • PREPARATION OF APREPITANT
    Publication number: 20110094321
    Abstract: A process for preparing aprepitant.
    Type: Application
    Filed: October 6, 2006
    Publication date: April 28, 2011
    Applicants: DR. REDDY'S LABORATORIES LIMITED, DR. REDDY'S LABORATORIES, INC.
    Inventors: Pravinchandra Jayantilal Vankawala, Ravi Ram Chandrasekhar Elati, Naveen Kumar Kolla, Subrahmanyeswara Rao Chlamala, Srinivas Gangula
  • Process for preparation of celecoxib
    Patent number: 7919633
    Abstract: There is provided a process for preparation of celecoxib by reacting 4,4,4-trifluoro-1-[4-(methyl)phenyl]butane-1,3-dione with 4-sulphonamidophenylhydrazine or its salt in a solvent medium that contains an alkyl ester. There is also provided a process for the purification of celecoxib using aromatic hydrocarbon solvents.
    Type: Grant
    Filed: March 19, 2008
    Date of Patent: April 5, 2011
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: Raghupathi Reddy Anumula, Goverdhan Gilla, Sampath Alla, Thirupathi Reddy Akki, Yakambram Bojja
  • Formulations Comprising Triptain Compounds
    Publication number: 20110077281
    Abstract: The invention provides a pharmaceutical composition for intranasal administration comprising a salt of sumatriptan or a physiologically acceptable solvate thereof, an alkyl glycoside or saccharide alkyl ester and optionally at least one pharmaceutically acceptable excipient, wherein the said composition provides Tmax value of less than 30 minutes upon said administration. Other aspects and embodiments are contemplated and described. The invention also provides a pharmaceutical composition for intranasal administration comprising a triptan, a pharmaceutically acceptable vehicle and a mucosal permeation enhancer, wherein upon said administration said composition provides a Tmax substantially equivalent to subcutaneous administration of said triptan. Other aspects and embodiments are contemplated and described.
    Type: Application
    Filed: June 17, 2010
    Publication date: March 31, 2011
    Applicant: Dr. Reddy's Laboratories Limited
    Inventors: Rajesh Gandhi, Sreekanth Manikonda, Arun Jana, Sameer Shrinivas Kunte
  • PROCESS FOR PREPARING (2R,3S/2S,3R)-2-(2,4-DIFLUOROPHENYL)-3-(5-FLUOROPYRIMIDIN-4-YL)-1-(1H-1,2,4-TRIAZOL-1-YL)BUTAN-2-OL
    Publication number: 20100292473
    Abstract: Voriconazole is prepared by a process comprising condensing 1-(2,4-difluorophenyl)-2-(1H-1,2,4-triazole-1-yl)ethanone with 4-chloro-6-ethyl-5-fluoropyrimidine, in a ketone, ether, aliphatic hydrocarbon, or aromatic hydrocarbon solvent, to give (2R,3S/2S,3R)-3-(4-chloro-5-fluoropyrimidin-6-yl)-2-(2,4-diflurophenyl)-1-(1H-1,2,4-triazole-1-yl)butan-2-ol.
    Type: Application
    Filed: June 10, 2010
    Publication date: November 18, 2010
    Applicants: DR. REDDY'S LABORATORIES LIMITED, DR. REDDY'S LABORATORIES, INC.
    Inventors: Venkataraman Sundaram, Venkata Bhaskara Rao Uppala, Surya Prabhakar Akundi, Venkateswarlu Muvva, Vijayawardhan Chitta, Alekhya Donthula, Manoj Ramesh Kharkar, Surya Narayana Devarakonda, Subba Reddy Peddireddy
  • Method for analyzing activated polyethylene glycol compounds
    Patent number: 7824919
    Abstract: A chemical analysis method for the determination of RO(CH2CH2O)nH, RO(C2H4O)nA, and AO(C2H4O)nA in a mixture thereof, wherein R is an alkyl group, A is a functional group for coupling with a surface or a biologically active material or another thing of use and n is an integer greater than 10. The method includes the step of chromatographing a sample of the mixture by liquid chromatography under critical conditions to determine the relative amounts of RO(CH2CH2O)n H, RO(C2H4O)nA, and AO(C2H4O)nA in the mixture. In addition a chemical analysis method for the determination of RO(CH2CH2O)nH, RO(C2H4O)nA, and AO(C2H4O)nA in a mixture thereof, wherein R is an alkyl group, A is a functional group for coupling with a biologically active material and n is an integer greater than 10. The method includes two steps.
    Type: Grant
    Filed: March 4, 2005
    Date of Patent: November 2, 2010
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: Ross A. Wallingford, Maciej Turowski
  • Method for making polyethylene glycol carbonates
    Patent number: 7816484
    Abstract: A method for preparing a polyalkylene glycol carbonate is disclosed comprising reacting a hydroxyl functional polyalkylene glycol and a reagent selected from carbonates and chloroformates in the presence of an aromatic solvent and an amine.
    Type: Grant
    Filed: February 27, 2007
    Date of Patent: October 19, 2010
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventor: Daniel E. Verral
  • BORTEZOMIB AND PROCESS FOR PRODUCING SAME
    Publication number: 20100226597
    Abstract: The present application provides a process for the preparation of Bortezomib, its intermediates and process for crystalline forms of Bortezomib.
    Type: Application
    Filed: September 12, 2008
    Publication date: September 9, 2010
    Applicants: DR. REDDY'S LABORATORIES LIMITED, DR. REDDY'S LABORATORIES, INC.
    Inventors: Raghavendracharyulu Venkata Palle, Rajasekhar Kadaboina, Veerendeer Murki, Amarendhar Manda, Nageshwar Gunda, Ramaseshagiri Rao Pulla, Mallesha Hanmanthu, Narasimha Naidu Mopidevi, Suresh Kumar Ramdoss
  • Polymorphic forms of ziprasidone and its hydrochloride salt and process for preparation thereof
    Patent number: 7790886
    Abstract: The present invention is related to crystalline forms of ziprasidone and its hydrochloride salt and an amorphous form of ziprasidone hydrochloride and the process for the preparation thereof. The crystalline forms and amorphous form of the invention are suitable for pharmaceutical purposes in the treatment of psychosis. The processes of the invention are simple, non-hazardous and commercially suitable.
    Type: Grant
    Filed: January 5, 2009
    Date of Patent: September 7, 2010
    Assignees: Dr. Reddy's Laboratories, Inc., Dr. Reddy's Laboratories Limited
    Inventors: Manne Satyanarayana Reddy, Thirumalai Rajan Srinivasan, Venka Bhaskara Rao Uppala, Mummadi Venkatesh, Akundi Surya Prabhakar
  • Ziprasidone process
    Patent number: 7777037
    Abstract: A process for preparing ziprasidone having low levels of keto ziprasidone and hydroxy ziprasidone impurities.
    Type: Grant
    Filed: October 26, 2005
    Date of Patent: August 17, 2010
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: Sundaram Venkataraman, Uppala Venkata Bhaskara Rao, Venkateswarlu Muvva, Vijayawardhan Chitta
  • Process for making crystalline form I of clopidogrel hydrogen sulphate
    Patent number: 7772398
    Abstract: A process for preparation of crystalline Form I of clopidogrel hydrogen sulphate, that include separating the crystalline Form I of clopidogrel hydrogen sulphate from a solution of clopidogrel freebase in a solvent, which is 2-propanol or 2-butanol is provided.
    Type: Grant
    Filed: March 11, 2005
    Date of Patent: August 10, 2010
    Assignees: Dr. Reddy's Laboratories, Inc., Dr. Reddy's Laboratories Limited
    Inventors: Eswaraiah Sajja, Raghupathi Reddy Anumula, Bhaskara rao Venkata Uppala
  • ORLISTAT PHARMACEUTICAL FORMULATIONS
    Publication number: 20100196464
    Abstract: Solid pharmaceutical formulations are prepared using compositions comprising orlistat and having average particle sizes less than about 250 ?m.
    Type: Application
    Filed: September 17, 2008
    Publication date: August 5, 2010
    Applicants: DR. REDDY'S LABORATORIES LIMITED, DR. REDDY'S LABORATORIES, INC.
    Inventors: Soma Sekhar Kothamasu, Arti Sah, Uma Sowjanya Asapu, Maheswara Reddy Arumalla
  • DOCETAXEL PROCESS AND POLYMORPHS
    Publication number: 20100197944
    Abstract: Processes for preparing substantially pure docetaxel, new crystalline forms of docetaxel and processes for preparation thereof, processes for preparing docetaxel trihydrate, and pharmaceutical compositions comprising docetaxel.
    Type: Application
    Filed: July 3, 2008
    Publication date: August 5, 2010
    Applicants: DR. REDDY'S LABORATORIES LIMITED, DR. REDDY'S LABORATORIES, INC.
    Inventors: Raghavendracharyulu Venkata Palle, Sekhar Munaswamy Nariyam, Rajasekhar Kadaboina, Lankeshwararao Matti, Sridhar Vasam, Shravan Kumar Komati, Siva Reddy Makireddy
  • Crystalline forms of fexofenadine and its hydrochloride
    Patent number: 7700779
    Abstract: The present invention is related to novel polymorph of Fexofenadine and Fexofenadine hydrochloride of formula 1 and process of preparation thereof. The present invention is also directed to provide pure novel polymorphs of Fexofenadine and its hydrochloride by a simple process which is cost effective, commercially viable and environment friendly.
    Type: Grant
    Filed: July 31, 2001
    Date of Patent: April 20, 2010
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: M. Satyanarayana Reddy, S. Thirumalai Rajan, U. V. Bhaskara Rao
  • AMORPHOUS VALGANCICLOVIR HYDROCHLORIDE
    Publication number: 20100081809
    Abstract: The present application relates to amorphous forms of valganciclovir salts such as the hydrochloride and processes for their preparation.
    Type: Application
    Filed: October 28, 2009
    Publication date: April 1, 2010
    Applicants: DR. REDDY'S LABORATORIES LIMITED, DR. REDDY'S LABORATORIES, INC.
    Inventors: Surya Narayana Devarakonda, Sesha Reddy Yerraguntla, Venu Nalivela, Arjun Kumar Tummala
  • TREATMENT AND PREVENTION OF CARDIOVASCULAR EVENTS
    Publication number: 20100068269
    Abstract: A pharmaceutical dosage form for treating or preventing cardiovascular events comprises therapeutic amounts of: a ?-adrenergic receptor antagonist, a diuretic, or both; a cholesterol-lowering agent; an inhibitor of the renin-angiotensin system; and aspirin.
    Type: Application
    Filed: November 19, 2009
    Publication date: March 18, 2010
    Applicants: DR. REDDY'S LABORATORIES LIMITED, DR. REDDY'S LABORATORIES, INC.
    Inventors: Badal Kumar Sasmal, Billa Praveen Reddy, Vijay Dinanathji Nasare, Mailatur Sivaraman Mohan
  • PROCESS FOR PREPARATION OF SOLID MONTELUKAST
    Publication number: 20100063291
    Abstract: A process for preparation of montelukast or a salt thereof is provided, the process including reacting a late intermediate compound which is 2-[1-[1-R-3-[2-(7 chloro quinolin-2-yl)vinyl [phenyl]-3-[2-methoxy carbonyl phenyl]propyl sulfonyl methyl]cyclo propyl]acetic acid or a salt thereof with methyl magnesium chloride or methyl magnesium bromide in an organic solvent. In one embodiment, the process includes reacting an earlier intermediate compound which is methyl 2-(3-R-(3-(2-(7-chloro 2-quinolinyl)-ethenyl)-3 hydroxy propyl)benzoate with methane sulfonyl chloride or toluene sulfonyl chloride to obtain a mesylated or tosylated derivative of the earlier intermediate compound; followed by a reaction of the mesylated or tosylated derivative with 1-mercapto methyl cyclopropane acetic acid in a polar solvent in a presence of a base to obtain the late intermediate compound.
    Type: Application
    Filed: November 17, 2009
    Publication date: March 11, 2010
    Applicants: DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LIMITED
    Inventors: Buchi Reddy Reguri, Satyanarayana Bollikonda, Veera Venkata Naga Chandra Sekhar Bulusu, Ravi Kumar Kasturi, Sanjeev Kumar Aavula
  • Process for preparing valsartan
    Patent number: 7659406
    Abstract: A process for preparing valsartan.
    Type: Grant
    Filed: January 3, 2006
    Date of Patent: February 9, 2010
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: Pratap Reddy Padi, Satya Narayana Bollikonda, Ananda Mohan Jasty, Suma Latha Yasareni, Vishal Dayaram Parmar
  • PREPARATION OF AMORPHOUS HYDROUS ESOMEPRAZOLE MAGNESIUM
    Publication number: 20100016606
    Abstract: A hydrate of esomeprazole magnesium in the form of an amorphous solid is provided. Methods of preparation and use of, as well as formulation containing the hydrate of esomeprazole magnesium in the form of an amorphous solid are also provided.
    Type: Application
    Filed: September 28, 2009
    Publication date: January 21, 2010
    Applicants: DR. REDDY'S LABORATORIES LIMITED, DR. REDDY'S LABORATORIES, INC.
    Inventors: Manne Satyanarayana Reddy, Muppa Kishore Kumar, Koilkonda Purandhar, Keshaboina Sreenath