Patents Assigned to Dr. Rentschler Arzneimittel GmbH & Co.
  • Patent number: 5614491
    Abstract: The present invention pertains to cyclosporin-containing liquid preparations for oral or parenteral administration, as well as to a process for preparing same. Besides the active ingredient cyclosporin, the preparations contain a polyoxyethylene glycerol fatty acid monoester and a monohydric and/or polyhydric alcohol(s). The preparations are stable and well tolerated, and they have higher bioavailability than the preparations known currently.
    Type: Grant
    Filed: November 30, 1994
    Date of Patent: March 25, 1997
    Assignee: Dr. Rentschler Arzneimittel GmbH & Co.
    Inventors: Hatto Walch, Monika Fleck, Klaus Neuer
  • Patent number: 5071642
    Abstract: Solid drug formulations for oral administration containing one or more dihydropyridines in doses of between 10 and 240 mg and suitable to be administered as a single dose per day for the treatment of circulatory disorders and high blood pressure.
    Type: Grant
    Filed: October 21, 1987
    Date of Patent: December 10, 1991
    Assignee: Dr. Rentschler Arzneimittel GmbH & Co.
    Inventors: Wolfgang Lahr, Hans Kohne, Frank Musculus, Hein-Uwe Schmersahl
  • Patent number: 4916132
    Abstract: The present invention relates to the use of dihydroergotamine and its salts for the local treatment of trophic disturbances, to drug forms for the local application of dihydroergotamine for the treatment of trophic disturbances and to methods for the production thereof, the concentrations of active substance in the drug compositions being between 0.001 and 99.9% by weight.
    Type: Grant
    Filed: March 22, 1988
    Date of Patent: April 10, 1990
    Assignee: Dr. Rentschler Arzneimittel GmbH & Co.
    Inventor: Hubert Seibel
  • Patent number: 4880634
    Abstract: An excipient system containing a drug for peroral administration in the form of an ultrafine aqueous, colloidal suspension of lipid nano-pellets comprised of lipids and a surfactant of which the particle diameters of the nano-pellets range from 50-1,000 nm, preferably from 80-800 nm, the ratio of lipid to surfactant in the lipid nano-pellets ranging from 1:0.1 to 1:2.2, preferably from 1:0.22 to 1:1.2, especially from 1:1 to 1:0.22, and where the lipid nano-pellets are present in the suspension in a concentration of from 1-20% by weight. The lipid nano-pellets can be provided with pharmacologically active substances, making possible improved biological availability upon peroral administration.
    Type: Grant
    Filed: June 26, 1987
    Date of Patent: November 14, 1989
    Assignee: Dr. Rentschler Arzneimittel GmbH & Co.
    Inventor: Peter Speiser
  • Patent number: 4855300
    Abstract: A pharmaceutical combination preparation and method for the treatment of circulatory disturbances comprising a dihydropyridine of the formula ##STR1## in which --R.sub.1, is a CH.sub.3 --O--CH.sub.2 --CH.sub.2 -- or CH.sub.3 group; R.sub.2 is a ##STR2## or CH.sub.3 --CH.sub.2 -- group; R.sub.3 is 4, NO.sub.2 or CL; and R.sub.2 is NO.sub.2, H or CL; and pharmaceutically suitable salts thereof; as active substance A and Pentoxifylline as active substance B, the quantity ratios of A:B being from about 1:150 to about 1:2.
    Type: Grant
    Filed: February 4, 1987
    Date of Patent: August 8, 1989
    Assignee: Dr. Rentschler Arzneimittel GmbH & Co.
    Inventors: Kumaresh Nandi, Helga Fischer, Wilfried Herrmann, Hans Kohne, Wolfgang Lahr, Hein U. Schmersahl, Hatto Walch
  • Patent number: 4172013
    Abstract: An apparatus for the mass growth of cells, characterized by a plurality of flat troughs which form a stack, seated in an airtight and liquid-tight manner on each other at their free outer edges, wherein, in two corners of each trough, there are provided two overflows which are arranged spaced above the bottom of the trough and open toward the next lower trough, and wherein the overflows of the different troughs are at least approximately aligned, and wherein the overflows of the uppermost and lowermost troughs can be closed, the individual troughs being connected with each other, and a method for the mass growth of diploid cells utilizing the same, are disclosed.
    Type: Grant
    Filed: May 27, 1977
    Date of Patent: October 23, 1979
    Assignee: Dr. Rentschler Arzneimittel GmbH & Co.
    Inventors: Rastislav Skoda, Valdemar Pakos