Patents Assigned to Dr. Rentschler, Arzneimmittel GmbH & Co.
  • Patent number: 4894235
    Abstract: An improved form of administration of 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridine-dicarboxylic acid-dimethylester (i.e., Nifedipine) is provided in which the Nifedipine is molecularly dispersed wihtin a solidified melt of polyethylene glycols which are liquid, semi-solid and solid at room temperature. The weight ratio of liquid to non-liquid polyethylene glycols in the solidified melt ranges from about 7:23 to 23:7, the solidification temperature of the mixture ranges from about 25.degree. C. to 62.degree. C. and the mixture has a viscosity of from about 1 to 180,000 poise when measured at 20.degree. C. in admixture with up to about 40 percent by weight of water.
    Type: Grant
    Filed: October 3, 1985
    Date of Patent: January 16, 1990
    Assignee: Dr. Rentschler, Arzneimmittel GmbH & Co.
    Inventors: Hans Kohne, Wolfgang Lahr, Hein U. Schmersahl