Patents Assigned to Dr. Willmar Schwabe GmbH & Co.
  • Publication number: 20220080006
    Abstract: A process prepares a rapidly disintegrating tablet with a disintegration time of at most 15 minutes for the peroral administration of a dry extract of the leaves of Ginkgo biloba, and with a total weight of the tablet of between 150 mg and 300 mg per 100 mg of ginkgo extract contained. Rapidly disintegrating tablets containing dry extract of the leaves of Ginkgo biloba can be prepared, which, due to their smaller dimensions, are easier to take than the tablets used hitherto. In a preferred form, the tablets do not contain lactose and are therefore also well tolerated.
    Type: Application
    Filed: January 8, 2020
    Publication date: March 17, 2022
    Applicant: DR. WILLMAR SCHWABE GMBH & CO. KG
    Inventors: Joachim HERRMANN, Andreas Rothe
  • Patent number: 10357530
    Abstract: The present invention relates to a combination of valerian root extract and lavender oil treating of sleep disorders, as well as to a combination of preparation comprising valerian root extract and lavender oil.
    Type: Grant
    Filed: June 10, 2015
    Date of Patent: July 23, 2019
    Assignee: Dr. Willmar Schwabe GmbH & Co. KG
    Inventors: Wilfried Dimpfel, Michael Nöldner
  • Patent number: 10028986
    Abstract: The present invention relates to an improved multistep method for the production of an extract of Ginkgo biloba leaves for use as a drug.
    Type: Grant
    Filed: January 12, 2015
    Date of Patent: July 24, 2018
    Assignee: Dr. Willmar Schwabe GMBH & Co., KG
    Inventors: Frank Waimer, Steffen Reinhard, Hermann Hauer
  • Patent number: 9592261
    Abstract: The invention relates to a plant extract combination of ginkgo and ginseng which is effective especially in a (synergistic) over-additive manner and optionally comprises whitethorn extract. Ginseng is used in the form of an ethanol/ethanol/water extract while ginkgo is used in the form of an acetone/acetone-water extract, for example, and the active extracts are prepared at specific quantitative ratios, particularly <1.1:1, thus unexpectedly boosting the prevention or also the treatment of a decline in the mental capacity related to age or also other disorders.
    Type: Grant
    Filed: September 9, 2008
    Date of Patent: March 14, 2017
    Assignee: Dr. Willmar Schwabe GmbH & Co. KG
    Inventors: Rolf D. Beutler, Karlheinz Schmidt
  • Patent number: 8642099
    Abstract: The present invention relates to an improved multi-step method for preparing an extract from ginkgo biloba having a reduced content of 4?-O-methyl pyridoxine and/or biflavones, wherein the depletion is carried out by filtration over an adsorber resin and/or an ion exchanger and the substances to be removed are retained on the resin. The invention further relates to an extract from ginkgo biloba having a reduced content of 4?-O-methyl pyridoxine and/or biflavones, which is obtainable by the method according to the present invention, as well as to its use.
    Type: Grant
    Filed: July 9, 2008
    Date of Patent: February 4, 2014
    Assignee: Dr. Willmar Schwabe GmbH & Co. KG
    Inventors: Clemens Erdelmeier, Hermann Hauer, Egon Koch, Friedrich Lang
  • Publication number: 20100310653
    Abstract: The present invention relates to the use of an extract made of leaves of Ginkgo biloba for the production of a preparation, or an extract made of leaves of Ginkgo biloba as an agent for the treatment and prophylaxis of the dementia syndrome, the early stages and pre-stages thereof, wherein 180 to 300 mg of Ginkgo extract is administered once a day.
    Type: Application
    Filed: December 18, 2008
    Publication date: December 9, 2010
    Applicant: DR. WILLMAR SCHWABE GMBH & CO. KG
    Inventors: Joachim Herrmann, Robert Hörr
  • Publication number: 20100112096
    Abstract: The invention relates to production methods for obtaining dry extracts from Pelargonium sidoides and/or Pelargonium reniforme, extracts which may be obtained according to said method, and pharmaceutical products comprising such extracts.
    Type: Application
    Filed: April 4, 2008
    Publication date: May 6, 2010
    Applicant: DR. WILLMAR SCHWABE GMBH & CO., KG
    Inventors: Joachim Herrmann, Marc Thöle
  • Publication number: 20090142428
    Abstract: The present invention relates to extracts from the bark of corynanthe species, in particular corynanthe pachyceras as well as to their use for the therapy and prophylaxis of diseases of the lower urinary tract, sexual disorders, lipid metabolism disorders, cardiovascular diseases and acute and chronic pain conditions. The present invention further relates to medicaments, dietetic food products and pharmaceutical preparations containing these extracts.
    Type: Application
    Filed: November 7, 2006
    Publication date: June 4, 2009
    Applicant: DR. WILLMAR SCHWABE GMBH & CO. KG
    Inventors: Egon Koch, Hermann Hauer
  • Patent number: 7381429
    Abstract: The invention relates to extracts from Sophora species, to a method for producing the same and to their use in the prophylaxis and therapy of pathological conditions that are caused by estrogen deficiency or by other hormonal dysregulations.
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: June 3, 2008
    Assignee: Dr. Willmar Schwabe GmbH & Co.
    Inventors: Clemens Erdelmeier, Hermann Jaggy, Egon Koch
  • Publication number: 20080020068
    Abstract: The present invention relates to the use of trisubstituted benzopyranones for the treatment or propylaxis of pathological conditions associated with oxidative stress and/or inflammatory reactions as well as to novel trisubstituted benzopyranones and the physiologically acceptable salts thereof. The present invention further relates to plant extracts, medicaments, dietetic food products and pharmaceutical preparations containing these compounds.
    Type: Application
    Filed: June 30, 2005
    Publication date: January 24, 2008
    Applicant: Dr.Willmar Schwabe GmbH & Co. KG
    Inventors: Stefan Germer, Hermann Hauer, Egon Koch, Karl Schotz
  • Patent number: 7166310
    Abstract: The invention relates to an improved and stable (i.e. color-stable and, optionally, stable with regard to its hyperforin content) extract from the overground parts of Hypericum perforatum L., to a method for the preparation thereof, and to pharmaceutical preparations and topical medicaments that contain this extract; in particular, gels for treating skin and mucous membrane irritations and disorders such as acne, atopic dermatitis, neuro-dermatitis, psoriasis, stomatitis, herpes zoster, herpes labialis (lip herpes), warts, varicella (chicken-pox), sores, burns and other bacterial and viral skin and mucous membrane infections and skin disorders that are accompanied by cell proliferation and inflammation.
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: January 23, 2007
    Assignee: Dr. Willmar Schwabe GmbH & Co.
    Inventors: Egon Koch, Clemens Erdelmeier, Joachim Herrmann
  • Publication number: 20020114832
    Abstract: The invention provides improved pharmaceutical preparations comprising peppermint oil and caraway oil for the treatment of dyspeptic complaints and cramps in the gastrointestinal region. In particularly preferred embodiments, preparations of the invention comprise high dosages of peppermint oil and caraway oil in a delayed-release form which also preferably consists of an enteric-coated soft gelatin capsule. Related methods also are disclosed.
    Type: Application
    Filed: December 11, 2000
    Publication date: August 22, 2002
    Applicant: Dr. Willmar Schwabe GmbH & Co.
    Inventors: Joachim Herrmann, Rainer Oschmann, Karl-Heinz Stumpf
  • Patent number: 6399099
    Abstract: The invention relates to effervescent compositions containing a dry extract of ginkgo biloba and an effervescent mixture. By dissolving the mixture in water a virtually clear and almost neutral solution is produced which is stable during the period of use.
    Type: Grant
    Filed: September 17, 1997
    Date of Patent: June 4, 2002
    Assignee: Dr. Willmar Schwabe GmbH & Co.
    Inventor: Rainer Oschmann
  • Publication number: 20020031560
    Abstract: Disclosed is an improved extract of Hypericum perforatum L. (St. John's wort) containing Hyperforin, in which the Hyperforin is stabilized against decomposition or degradation by means of a stabilizer.
    Type: Application
    Filed: August 23, 2001
    Publication date: March 14, 2002
    Applicant: Dr. Willmar Schwabe GmbH & Co.
    Inventors: Clemens Erdelmeier, Eckhart Grethlein, Friedrich Lang, Rainer Oschmann, Karl-Heinz Stumpf
  • Patent number: 6328999
    Abstract: The invention relates to extracts from ginkgo biloba leaves with a reduced 4′-O-methyl pyridoxine and biflavones content, to a method for the production thereof and to medicaments containing said extracts.
    Type: Grant
    Filed: May 25, 2000
    Date of Patent: December 11, 2001
    Assignee: Dr. Willmar Schwabe GmbH & Co.
    Inventor: Klaus-Peter Schwabe
  • Patent number: 6288109
    Abstract: The invention relates to a novel 2H-1-pyran-2-ones of general formula (I), wherein R1 represents an alkyl radical with 2-5 C atoms, a cycloakyl radical with 4-6 C atoms, a cycloalkyl radical with 4-8 C atoms or an alkoxy alkyl radical with a total of 3-5 C atoms and R2 represents a 2-(3, 4-methylene dioxyphenyl) radical or a 2-phenyl ethenyl radical substituted with R3, R4 and R5 in positions 3, 4 and 5, whereby independently from each other R3 and R5 represent methoxy or ethoxy and R4 is a straight chain or branched alkoxy radical with 1-5 C atoms, an alkenyl radical with 3-5 C atoms, a cycloalkoxy radical with 4-6 C atoms, a cycloalkyl radical with 4-8 C atoms or an alkoxy alkoxy radical with a total of 3-5 C atoms. The invention also relates to a method for producing said compunds in addition to novel untermediate products and to a method for the production thereof.
    Type: Grant
    Filed: May 12, 2000
    Date of Patent: September 11, 2001
    Assignee: Dr. Willmar Schwabe GmbH & Co.
    Inventors: Shyam Sunder Chatterjee, Hermann Hauer
  • Patent number: 6280737
    Abstract: The disclosure relates to extracts from Harpagophytum procumbens with a high harpagoside content, to processes for producing them, such extracts containing no components capable of stimulating the synthesis of thromboxane B2 and cysteinylleucotrienes, and to pharmaceutical compositions containing such extracts.
    Type: Grant
    Filed: February 22, 1999
    Date of Patent: August 28, 2001
    Assignee: Dr. Willmar Schwabe GmbH & Co.
    Inventors: Karl-Heinz Stumpf, Hermann Jaggy, Rainer Oschmann, Egon Koch, Thomas Simmet
  • Patent number: 6241988
    Abstract: Disclosed is an improved extract of Hypericum perforatum L. (St. John's wort) containing Hyperforin, in which the Hyperforin is stabilized against decomposition or degradation by means of a stabilizer.
    Type: Grant
    Filed: February 18, 2000
    Date of Patent: June 5, 2001
    Assignee: Dr. Willmar Schwabe GmbH & Co.
    Inventors: Clemens Erdelmeier, Eckhart Grethlein, Friedrich Lang, Rainer Oschmann, Karl-Heinz Stumpf
  • Patent number: 5512286
    Abstract: The present application relates to an extract from the leaves of Ginkgo biloba containing most of the flavone glycosides, ginkgolides and bilobalide originally present in the leaves, characterized in that it is essentially free of components of the leaves with serum-precipitating and/or haemagglutinating properties, method of its preparation and pharmaceutical compositions containing the extract.
    Type: Grant
    Filed: February 23, 1994
    Date of Patent: April 30, 1996
    Assignee: Dr. Willmar Schwabe GmbH & Co.
    Inventor: Klaus-Peter Schwabe
  • Patent number: 5428038
    Abstract: Novel 2H-1-benzopyran-2-ones (coumarin derivatives) of the general formula (I) are provided: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, X and Y are defined as in the specification, and the addition compounds thereof with physiologically compatible acids, intermediates and methods for the preparation thereof. The coumarin compounds possess a neuroprotective and anti-allergic action.
    Type: Grant
    Filed: October 8, 1993
    Date of Patent: June 27, 1995
    Assignee: Dr. Willmar Schwabe GmbH & Co.
    Inventors: Shyam S. Chatterjee, Michael Noldner, Hermann Hauer, Egon Koch