Abstract: An inline drain sanitizing system, includes: a manifold assembly including an inlet port, an outlet port, and a treatment port, wherein: the inlet port is configured to be couplable to a condensate supply line and receive unsanitized condensate, and the outlet port is configured to be couplable to a condensate drain line and provide sanitized condensate; and a treatment subsystem configured to interface with the treatment port and process the unsanitized condensate to generate the sanitized condensate.