Abstract: A two-wire, admittance-responsive instrument system in which a transmitter, receiver and calibrator are connected by a two-wire transmission line is disclosed. The calibrator repetitively transmits a calibration enabling signal causing the transmitter to increment a reference admittance for comparison to a sensed admittance corresponding to a known physical condition. The calibrator monitors the bistable output signals transmitted by the transmitter in the calibration mode, which changes state when the incremented reference admittance bears a predetermined relationship to the sensed admittance. The calibrator may then transmit additional calibration enabling signals causing preload to be established for transmitter operation.