Patents Assigned to DRIVINGFORCE THERAPEUTICS
  • Isothiocyanate compounds and isothiocyanate XPO1 protein inhibitor drugs thereof
    Patent number: 10315990
    Abstract: The present invention provides an isothiocyanate compound and its application. The compound is an aryl-substituted isothiocyanate compound that has a structure of the general formula I. The isothiocyanate compound of the present invention has very good solubility in water, far better inhibitory activity for XPO1 protein than other non-aryl substituted congeneric compounds, little side effects, and good biological safety and bioavailability, and is quite suitable for clinical application. Therefore, the isothiocyanate compound would have tremendous potential market space and economic benefits.
    Type: Grant
    Filed: February 3, 2016
    Date of Patent: June 11, 2019
    Assignee: DRIVINGFORCE THERAPEUTICS
    Inventor: Yongliang Yang
  • ISOTHIOCYANATE COMPOUND AND APPLICATION THEREOF
    Publication number: 20180029979
    Abstract: The present invention provides an isothiocyanate compound and its application. The compound is an aryl-substituted isothiocyanate compound that has a structure of the general formula I. The isothiocyanate compound of the present invention has very good solubility in water, far better inhibitory activity for XPO1 protein than other non-aryl substituted congeneric compounds, little side effects, and good biological safety and bioavailability, and is quite suitable for clinical application. Therefore, the isothiocyanate compound would have tremendous potential market space and economic benefits.
    Type: Application
    Filed: February 3, 2016
    Publication date: February 1, 2018
    Applicant: DRIVINGFORCE THERAPEUTICS Co., Ltd.
    Inventor: Yongliang YANG