Patents Assigned to DRUG DELIVERY SOLUTIONS APS
  • Publication number: 20210000796
    Abstract: There is provided a topical formulation comprising a nucleophile, such as amino acids and most polypetides and/or a derivative thereof, for use in the treatment or prevention of itchy dry skin caused by urea, such as in uremic pruritus, of a subject. The amino acid may be histidine and the derivative may be a histidine degradation product, a peptide of histidine, a peptide of histidine and one or more additional amino acids, and a pharmaceutically-acceptable salt of histidine.
    Type: Application
    Filed: September 18, 2020
    Publication date: January 7, 2021
    Applicant: DRUG DELIVERY SOLUTIONS APS
    Inventors: Torkil MENNE, Johan SELMER, Jesper LANGE, Michelle GEORGIOU, Derek WHEELER, David EVANS
  • Patent number: 10806721
    Abstract: There is provided a topical formulation comprising a nucleophile, such as amino acids and most polypeptides and/or a derivative thereof, for use in the treatment or prevention of itchy dry skin caused by urea, such as in uremic pruritus, of a subject. The amino acid may be histidine and the derivative may be a histidine degradation product, a peptide of histidine, a peptide of histidine and one or more additional amino acids, and a pharmaceutically-acceptable salt of histidine.
    Type: Grant
    Filed: June 16, 2017
    Date of Patent: October 20, 2020
    Assignee: DRUG DELIVERY SOLUTIONS APS
    Inventors: Torkil Menne, Johan Selmer, Jesper Lange, Michelle Georgiou, Derek Wheeler, David Evans