Abstract: Methods and compositions for reducing cholesterol levels are provided which involve administering an effective daily dosage of proanthocyanidin and niacin-bound chromium to a subject.
Abstract: A method is disclosed for preventing or treating the adverse physiological effects associated with cardiac disease by administering a purified proanthocyanidin composition to the person in an amount effective to prevent or reduce the adverse physiological effects.
Abstract: A method is disclosed for preventing and/or reducing stress-induced gastric injury by administering an amount of grape seed proanthocyanidin extract effective to inhibit injury is administered to persons identified as among those with or at risk for such injury.
Type:
Grant
Filed:
November 19, 1999
Date of Patent:
September 18, 2001
Assignee:
Dry Creek Nutrition, Inc
Inventors:
Debasis Bagchi, Manashi Bagchi, Sidney J. Stohs
Abstract: A method for preventing and/or reducing the toxicity of acetaminophen is disclosed. An amount of grape seed proanthocyanidin extract effective to inhibit toxicity of acetaminophen is administered before, simultaneous with, and/or after dosage of acetaminophen. This allows for increased therapeutic dosages of acetaminophen to be administered with reduced risk of toxic effects, and for prevention of toxic effects in people with special sensitivity to acetaminophen. A composition containing both acetaminophen and grape seed proanthocyanidin extract, allowing for ease of administration of an amount of grape seed proanthocyanidin extract effective to protect from toxicity, also is disclosed.