Patents Assigned to DSM IP Assets B.V.
-
Patent number: 11660100Abstract: Disclosed are radially expanding debridement tools configured to pass through an access channel present in a first tissue of a living being, expand radially, and create a void in a second tissue of the living being upon being advanced distally through the access channel and into the second tissue while being rotated, wherein the shape of the void comprises at least one step. Further disclosed are debridement systems and methods of treating tissue defects in living beings.Type: GrantFiled: January 25, 2019Date of Patent: May 30, 2023Assignee: DSM IP ASSETS B.V.Inventors: William T. Fisher, Timothy Ringeisen, Gino Bradica
-
Patent number: 11655485Abstract: The invention relates to a process for the production of ethanol comprising fermenting a (optionally liquefied) corn slurry under anaerobic conditions in the presence of a recombinant yeast; and recovering the ethanol, wherein said recombinant yeast functionally expresses a heterologous nucleic acid sequence encoding a glucoamylase having an amino acid sequence according to SEQ ID NO: 1 or which glucoamylase is a functional homologue thereof having a sequence identity of at least 80%, or which glucoamylase is a functional homologue which is derived, by way of one or more amino acid substitutions, deletions or insertions, from the amino acid sequence of SEQ ID NO: 1, and wherein the process comprises dosing a glucoamylase at a concentration of 0.05 g/L or less.Type: GrantFiled: August 15, 2019Date of Patent: May 23, 2023Assignee: DSM IP ASSETS B.V.Inventor: Hans Marinus Charles Johannes De Bruijn
-
Patent number: 11655267Abstract: The present disclosure relates oligosaccharide preparations suitable for use in nutritional compositions such as animal feed and methods of manufacturing the described oligosaccharide preparations. The present disclosure further relates to nutritional compositions that comprise the oligosaccharide preparations. The disclosed oligosaccharide preparations can be advantageous as an animal feed due to, at least in part, their prebiotic utility and the presence of anhydro-subunit containing oligosaccharides, which can be used to detect and/or determine the presence and content of the disclosed oligosaccharide preparations in the nutritional composition.Type: GrantFiled: November 8, 2019Date of Patent: May 23, 2023Assignee: DSM IP ASSETS B.V.Inventors: Manuela Baur, Estel Canet-Martinez, Ruediger Hainz, Ulrich Hoeller, Lisa Ann Laprade, John Michael Geremia, Ghislain Schyns
-
Patent number: 11649471Abstract: The present invention relates to a process for the production of one or more fermentation product from a sugar composition, comprising the following steps: a) fermentation of the sugar composition in the presence of a yeast belonging to the genera Saccharomyces, Kluyveromyces, Candida, Pichia, Schizosaccharomyces, Hansenula, Kloeckera, Schwanniomyces or Yarrowia: and b) recovery of the fermentation product, wherein the yeast comprises the genes araA, araB and araD and the sugar composition comprises glucose, galactose and arabinose.Type: GrantFiled: March 12, 2021Date of Patent: May 16, 2023Assignee: DSM IP ASSETS B.V.Inventors: Paul Klaassen, Gijsberdina Pieternella Van Suylekom, Bianca Elisabeth Maria Gielesen, Nicolette Jasmijn Broers, Beate Wiedemann, Wilhelmus Theodorus Antonius Maria De Laat
-
Patent number: 11649353Abstract: Disclosed are compositions that may be useful for forming synthetic membranes, methods of forming membranes therefrom, and membranes. In an embodiment, a membrane comprises a free hydrophilic polymer and a polyurethane, the polyurethane comprising a backbone comprising the reaction product of a diisocyanate, a polymeric aliphatic diol, and, optionally, a chain extender, wherein the backbone comprises a C2-C16 fluoroalkyl or C2-C16 fluoroalkyl ether, or the polyurethane comprises an endgroup comprising a C2-C16 fluoroalkyl or C2-C16 fluoroalkyl ether.Type: GrantFiled: August 28, 2018Date of Patent: May 16, 2023Assignee: DSM IP ASSETS B.V.Inventors: Jennifer Al-Rashid, John Zupancich, Chad Sugiyama
-
Patent number: 11643551Abstract: Disclosed are compositions that may be useful for forming synthetic membranes, methods of forming membranes therefrom, and membranes. In an embodiment, a membrane comprises a free hydrophilic polymer comprising a polyoxazoline, and a polyurethane, the polyurethane comprising a backbone comprising the reaction product of a diisocyanate, a polymeric aliphatic 5 diol, and optionally a chain extender.Type: GrantFiled: August 28, 2018Date of Patent: May 9, 2023Assignee: DSM IP ASSETS B.V.Inventors: Jennifer Al-Rashid, Jacob Riffey, Chad Sugiyama, John Zupancich
-
Patent number: 11639497Abstract: The present disclosure relates a polypeptide having UGT activity, which polypeptide comprises an amino acid sequence which, when aligned with a polypeptide having UGT activity comprising the sequence set out in SEQ ID NO: 2, comprises at least one substitution of an amino acid corresponding to any of amino acids at positions 35, 189, 280, 284, 285, 334 or 373, said positions being defined with reference to SEQ ID NO: 2 and wherein the polypeptide has one or more modified properties as compared with a reference polypeptide having UGT activity. A polypeptide according to the disclosure may be used in a recombinant cell for the production of steviol or a steviol glycoside.Type: GrantFiled: June 26, 2018Date of Patent: May 2, 2023Assignee: DSM IP ASSETS B.V.Inventors: Viktor Marius Boer, Johannes Gustaaf Ernst Van Leeuwen
-
Patent number: 11627752Abstract: The present invention relates to a method for producing a flavour composition comprising providing a slurry of yeast cell walls and contacting the slurry of yeast cell walls with a glucanase and with an endoprotease, followed by separating a liquid fraction by solid/liquid separation to provide the liquid flavour composition.Type: GrantFiled: March 8, 2022Date of Patent: April 18, 2023Assignee: DSM IP ASSETS B.V.Inventors: Bernadette Theresia Morel, Marco Alexander Van Den Berg
-
Patent number: 11623976Abstract: A process for the production of a thermoplastic elastomer containing hard segments (a) of a polyester and soft segments (b) containing repeating units derived from an aliphatic carbonate, in which process a precursor thermoplastic elastomer is subjected to solid state post condensation at a temperature between 140 and 170° C. Also claimed is the thermoplastic elastomer.Type: GrantFiled: November 12, 2020Date of Patent: April 11, 2023Assignee: DSM IP ASSETS B.V.Inventors: Ellen Van Hemelrijck, Wilhelmus Petrus Johannes Appel
-
Patent number: 11623939Abstract: The present invention is directed to a process for purifying natamycin, to an all-trans polyene amphoteric macrolide, to a composition comprising said polyene amphoteric macrolide and to a process for preparing said polyene amphoteric macrolide.Type: GrantFiled: August 15, 2019Date of Patent: April 11, 2023Assignee: DSM IP ASSETS B.V.Inventors: Alexander Lucia Leonardus Duchateau, Peter Philip Lankhorst, Willebrordus Bernardus Van Scheppingen
-
Patent number: 11624057Abstract: The invention relates to a recombinant cell, preferably a yeast cell comprising: a) one or more heterologous genes encoding a glycerol dehydrogenase activity; b) one or more genes encoding a dihydroxyacetone kinase (E.C. 2.7.1.28 and/or E.C. 2.7.1.29); c) one or more heterologous genes encoding a ribulose-1,5-biphosphate carboxylase oxygenase (EC 4.1.1.39, RuBisCO); and d) one or more heterologous genes encoding a phosphoribulokinase (EC 2.7.1.19, PRK); and optionally e) one or more heterologous genes encoding for a glycerol transporter. This cell can be used for the production of ethanol and advantageously produces little or no glycerol.Type: GrantFiled: March 17, 2021Date of Patent: April 11, 2023Assignee: DSM IP ASSETS B.V.Inventors: Paulus Petrus De Waal, Ingrid Maria Vugt-Van Lutz, Jozef Petrus Johannes Schmitz, Hans Marinus Charles Johannes De Bruijn
-
Patent number: 11607420Abstract: The present invention relates to a new formulation of specific nutritional ingredients (nutraceuticals) and/or pharmaceutical compounds.Type: GrantFiled: June 6, 2019Date of Patent: March 21, 2023Assignee: DSM IP ASSETS B.V.Inventors: Elger Funda, Odile Krainz
-
Patent number: 11608364Abstract: The disclosure provides a recombinant cell capable of producing a steviol glycoside, wherein the cell comprises a nucleic acid coding for a variant of a parent polypeptide, wherein the variant has steviol glycoside transport mediating activity, wherein the variant comprises an amino acid sequence which, when aligned with the amino acid sequence of the parent polypeptide, comprises at least one modification of the amino acid residue corresponding to any of the amino acids in the amino acid sequence of the parent polypeptide, wherein the variant has an improved ability to produce rebaudioside M and optionally other steviol glycosides extracellularly if compared with the parent polypeptide when measured under the same conditions.Type: GrantFiled: April 29, 2019Date of Patent: March 21, 2023Assignee: DSM IP ASSETS B.V.Inventors: Johannes Gustaaf Ernst Van Leeuwen, Viktor Marius Boer, Priscilla Zwartjens, Jos Van Vugt, René Marcel De Jong
-
Patent number: 11602503Abstract: The present invention relates to a new delivery system for nutritional ingredients (nutraceuticals). These nutritional ingredients are useful for gut and metabolic health in monogastric animals, especially in humans.Type: GrantFiled: October 30, 2018Date of Patent: March 14, 2023Assignee: DSM IP ASSETS B.V.Inventors: Elger Funda, Odile Krainz, Robert Steinert
-
Patent number: 11591367Abstract: The present invention relates to novel selective melanocortin-1 receptor (MC1R) agonists as well as the use thereof as skin tanning agents.Type: GrantFiled: October 2, 2017Date of Patent: February 28, 2023Assignee: DSM IP ASSETS B.V.Inventors: Marc Heidl, Eileen Jackson
-
Patent number: 11591360Abstract: The present invention is directed to a process for purifying natamycin, to an epoxide polyene amphoteric macrolide, to a composition comprising said polyene amphoteric macrolide and to a process for preparing said polyene amphoteric macrolide.Type: GrantFiled: August 15, 2019Date of Patent: February 28, 2023Assignee: DSM IP ASSETS B.V.Inventors: Alexander Lucia Leonardus Duchateau, Peter Philip Lankhorst, Willebrordus Bernardus Van Scheppingen
-
Patent number: 11576394Abstract: The present invention describes a intracellular produced lactase, which comprises less than 40 units arylsulfatase activity per NLU of lactase activity. The invention also provides a process comprising treating a substrate with an enzyme preparation, wherein the enzyme preparation is substantially free from arylsulfatase.Type: GrantFiled: February 6, 2018Date of Patent: February 14, 2023Assignee: DSM IP ASSETS B.V.Inventors: Petrus Jacobus Theodorus Dekker, Luppo Edens, Maximiliaan Peter Marie De Swaaf, Albertus Alard Van Dijk
-
Patent number: 11578292Abstract: The present invention relates to a process for reducing haze in a beverage comprising adding a protein arginine deiminase and a proline-specific endoprotease during preparation of the beverage. The invention further relates to a wort or beer comprising a protein arginine deiminase and a proline-specific endoprotease.Type: GrantFiled: March 26, 2019Date of Patent: February 14, 2023Assignee: DSM IP ASSETS B.V.Inventors: Loes Elizabeth Bevers, Johanna Henrica Gerdina Maria Mutsaers
-
Patent number: 11578171Abstract: The invention relates to a thermoplastic composition comprising (A) a semi-aromatic copolyamide comprising repeat units derived from diamine consisting primarily of tetramethylene diamine and hexamethylene diamine, or pentamethylene diamine and hexamethylene diamine, and dicarboxylic acid consisting primarily of terephthalic acid, having a VN of at least 100 ml/g; and (B) a reinforcing agent. The invention also relates to a plastic part made of the thermoplastic composition. The invention further relates to an automotive vehicle comprising a structural part made of the thermoplastic composition and to an electrical assembly comprising a plastic component made of the thermoplastic composition.Type: GrantFiled: December 8, 2017Date of Patent: February 14, 2023Assignee: DSM IP ASSETS B.V.Inventors: Rudy Rulkens, Frank Van Der Burgt
-
Patent number: 11578344Abstract: The present invention is related to a novel enzymatic process for production of retinoids via a multi-step process, which process includes the use of heterologous enzymes having activity in a carotene-producing host cell, particularly wherein such process results in high percentage of retinoids, in trans-isoform.Type: GrantFiled: September 25, 2018Date of Patent: February 14, 2023Assignee: DSM IP ASSETS B.V.Inventors: Nathalie Balch, Paul Blomquist, Reed Doten, Peter Houston, Ethan Lam, Jenna McMahon, Joshua Trueheart, Celine Viarouge