Patents Assigned to DSM IP Assets B.V.
  • Patent number: 10982235
    Abstract: The present invention relates to a process for the production of one or more fermentation product from a sugar composition, comprising the following steps: a) fermentation of the sugar composition in the presence of a yeast belonging to the genera Saccharomyces, Kluyveromyces, Candida, Pichia, Schizosaccharomyces, Hansenula, Kloeckera, Schwanniomyces or Yarrowia: and b) recovery of the fermentation product, wherein the yeast comprises the genes araA, araB and araD and the sugar composition comprises glucose, galactose and arabinose.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: April 20, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Paul Klaassen, Gijsberdina Pieternella Van Suylekom, Bianca Elisabeth Maria Gielesen, Nicolette Jasmijn Broers, Beate Wiedemann, Wilhelmus Theodorus Antonius Maria De Laat
  • Patent number: 10982113
    Abstract: The present patent application relates to a novel coating system, wherein the coating comprises Carnauba wax and at least one polysorbate. Furthermore it relates to compositions coated with such a coating system and the use of such compositions in the production of tablets.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: April 20, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Michael John Adams, Bruno Leuenberger, Loni Schweikert, Olivia Vidoni, Yan Zhang, Zhibing Zhang
  • Patent number: 10982195
    Abstract: The invention relates to a recombinant cell, preferably a yeast cell comprising: a) one or more heterologous genes encoding a glycerol dehydrogenase activity; b) one or more genes encoding a dihydroxyacetone kinase (E.C. 2.7.1.28 and/or E.C. 2.7.1.29); c) one or more heterologous genes encoding a ribulose-1,5-biphosphate carboxylase oxygenase (EC 4.1.1.39, RuBisCO); and d) one or more heterologous genes encoding a phosphoribulokinase (EC 2.7.1.19, PRK); and optionally e) one or more heterologous genes encoding for a glycerol transporter. This cell can be used for the production of ethanol and advantageously produces little or no glycerol.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: April 20, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Paulus Petrus De Waal, Ingrid Maria Vugt-Van Lutz, Jozef Petrus Johannes Schmitz, Hans Marinus Charles Johannes De Bruijn
  • Patent number: 10980249
    Abstract: The invention relates to the use of at least one bacterial phytase in combination with one or more protease(s) in animal feed for improving weight gain and/or Feed Conversion Ratio (FCR), wherein the phytase is administered in one or more of the following amounts (dosage ranges): 1,000 FYT/kg feed, 2,000 FYT/kg feed 3,000 FYT/kg feed and wherein the protease is administered in one of the following amounts (dosage ranges): 10,000 units/kg feed, 11,000, 12,000, 13,000, 14,000, 15,000, 16,000, 17,000, 18,000, 19,000, 20,000 units/kg feed.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: April 20, 2021
    Assignees: DSM IP Assets B.V., Novozymes A/S
    Inventors: Fidelis Fru, Aaron Joell Cowiesen, Inge Knap
  • Patent number: 10975009
    Abstract: The present invention relates to a selective reduction of specific aldehydes and ketones to their corresponding alcohols.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: April 13, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Matthias Beller, Werner Bonrath, Johannes Gerardus De Vries, Yuting Fan, Sandra Hinze, Laurent Lefort, Jonathan Alan Medlock, Pim Puylaert, Richard Van Heck
  • Patent number: 10966934
    Abstract: The present patent application relates to coated particles. These coated particles show improved properties when used in compressed tablets.
    Type: Grant
    Filed: February 16, 2018
    Date of Patent: April 6, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Jihane Achkar, Elger Funda, Loni Schweikert, Kai Urban, Olivia Brigitte Vidoni, Ernst Zedi
  • Patent number: 10968437
    Abstract: Factors For the Production and Accumulation of Polyunsaturated Fatty Acids (PUFAs) Derived from PUFA Synthases Abstract Disclosed are novel enhancing factor proteins of the PUFA synthase systems, nucleic acid molecules encoding the same, recombinant nucleic acid molecules and recombinant host cells comprising such nucleic acid molecules, genetically modified microorganisms comprising the same, and methods of making and using the same. Also disclosed are genetically modified microorganisms that have been genetically modified to express a PUFA synthase system for the production of PUFAs, wherein the microorganisms have been modified to express the novel enhancing factor proteins of the PUFA synthase system.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: April 6, 2021
    Assignee: DSM IP Assets B.V.
    Inventors: James George Metz, Jerry M. Kuner, David Glen McCaskill, Mendy Louise Foster
  • Patent number: 10952991
    Abstract: The present invention is made for the prevention of ketosis or minimizing the effects of ketosis in ruminant animals. This purpose is achieved by feeding to the animal biotin in combination with a mixture of at least two essential oil compounds selected from the group consisting of thymol, eugenol, meta-cresol, vaniline and guajacol. The present invention is useful because it is capable of preventing and/or inhibiting ketosis of calving ruminant animals and the subsequent need for veterinary treatment. In a preferred embodiment of a feeding concept for dairy cattle, especially calving dairy cattle, biotin being used in an amount sufficient to provide a daily dosage of 10 mg to 20 mg per head to which it is to be administered. It is at present contemplated that the essential oils are administered in amounts (total dosage ranges of essential oils) of 1 to 1.5 g per head per day.
    Type: Grant
    Filed: December 11, 2014
    Date of Patent: March 23, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Irmgard Immig, Wolfgang Steinberg, Joseph McGrath
  • Patent number: 10947573
    Abstract: The invention relates to a process for the preparation of a fermentation product from lignocellulosic material, comprising the following steps: a) optionally, pretreatment of the lignocellulosic material, b) optionally, washing of the optionally pretreated lignocellulosic material, c) enzymatic hydrolysis of the optionally washed and/or optionally pretreated lignocellulosic material using an enzyme composition comprising at least two cellulases and whereby the enzyme composition at least comprises LPMO, and optionally purifying the hydrolysed lignocellulosic material, d) fermentation of the hydrolysed lignocellulosic material to produce a fermentation product, and e) optionally, recovery of a fermentation product, wherein the amounts of formed hydrolysed oxidation products at the end of the enzymatic hydrolysis by the oxidation by LPMO of the lignocellulosic material containing cellulose and/or cello-oligosaccharides is kept between 3 to 80 g/kg glucan present in the lignocellulosic material by adding a s
    Type: Grant
    Filed: May 9, 2019
    Date of Patent: March 16, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Bertus Noordam, Loes Elizabeth Bevers, Rudy Francois Maria Jozef Parton, Michael Petrus Jozef Berkhout
  • Patent number: 10947515
    Abstract: The present invention relates to a recombinant host comprising a recombinant nucleic acid sequence encoding a polypeptide having at least about: a. 85% identity to the amino acid sequence set forth in SEQ ID NO: 1; b. 85% identity to the amino acid sequence set forth in SEQ ID NO: 3; c. 85% identity to the amino acid sequence set forth in SEQ ID NO: 6; d. 85% identity to the amino acid sequence set forth in SEQ ID NO: 9; e. 85% identity to the amino acid sequence set forth in SEQ ID NO: 11; f. 85% identity to the amino acid sequence set forth in SEQ ID NO: 14; g. 85% identity to the amino acid sequence set forth in SEQ ID NO: 17; h. 85% identity to the amino acid sequence set forth in SEQ ID NO: 20; i. 85% identity to the amino acid sequence set forth in SEQ ID NO: 22; or j. 85% identity to the amino acid sequence set forth in SEQ ID NO: 25.
    Type: Grant
    Filed: January 30, 2020
    Date of Patent: March 16, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Viktor Marius Boer, Johannes Gustaaf Emst Van Leeuwen, Priscilla Zwartjens, Catharina Petronella Antonia Maria Kolen
  • Patent number: 10941421
    Abstract: The present invention relates to processes for producing ethanol from lignocellulosic hydrolysates comprising, hexoses, pentoses and acetic acid, whereby genetically modified yeast cells are use that comprise an exogenous gene encoding an acetaldehyde dehydrogenase and a bacterial gene encoding an enzyme with NAD+-linked glycerol dehydrogenase activity. The process is further characterised in that glycerol is present in or fed into the culture medium, whereby the modified yeast cell ferments the hexoses, pentoses, acetic acid and glycerol to ethanol. The invention further relates to yeast cells for use in such processes. The yeast cells advantageously comprise genetic modifications that improve glycerol utilization such as modifications that increase one or more of dihydroxyacetone kinase activity and transport of glycerol into the cell.
    Type: Grant
    Filed: May 3, 2018
    Date of Patent: March 9, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Johannes Adrianus Maria De Bont, Aloysius Wilhelmus Rudolphus Hubertus Teunissen, Paul Klaassen, Wouter Willem Antonius Hartman, Shimaira Van Beusekom
  • Patent number: 10933002
    Abstract: The present invention relates to topical compositions comprising phytantriol and erythrulose as well as the use thereof for preservation boosting.
    Type: Grant
    Filed: December 4, 2018
    Date of Patent: March 2, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventor: Christine Mendrok-Edinger
  • Patent number: 10925850
    Abstract: The invention is directed to microbial oils containing omega-3 polyunsaturated fatty acids comprising docosahexaenoic acid, eicosapentaenoic acid, and optionally docosapentaenoic acid and dosage forms containing such oils.
    Type: Grant
    Filed: April 6, 2018
    Date of Patent: February 23, 2021
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, Paul Warren Behrens, Jon Milton Hansen, Joseph W. Pfeifer, III, Tracey Lynn Stahl, Ross Zirkle
  • Patent number: 10927399
    Abstract: The present invention relates to a method of identifying a heterologous polypeptide having enzymatic activity for converting pyruvate, acetaldehyde or acetate into acetyl-CoA in (the cytosol of) a yeast cell comprising: a) providing a mutated yeast cell comprising a deletion of at least one gene of the (PDH) by-pass, selected from the genes encoding the enzymes pyruvate decarboxylase (PDC), acetaldehyde dehydrogenase (ALD), and acetyl-CoA synthetase (ACS); b) transforming said mutated yeast cell with an expression vector comprising a heterologous nucleotide sequence encoding a candidate polypeptide having potential enzymatic activity for converting pyruvate, acetaldehyde or acetate into acetyl-CoA; c) testing said recombinant mutated yeast cell for its ability to grow on minimal medium containing glucose as sole carbon source, and d) identifying said candidate polypeptide as a heterologous polypeptide having enzymatic activity for converting pyruvate, acetaldehyde or acetate into acetyl-CoA in (the cytosol of
    Type: Grant
    Filed: October 3, 2013
    Date of Patent: February 23, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Ulrike Maria Mueller, Liang Wu, Lourina Madeleine Raamsdonk, Aaron Adriaan Winkler
  • Publication number: 20210045982
    Abstract: The present invention relates to topical compositions comprising at least one liquid UV-filter and a nano-sized 1,4-di(benzoxazol-2?-yl)benzene.
    Type: Application
    Filed: March 19, 2019
    Publication date: February 18, 2021
    Applicant: DSM IP Assets B.V.
    Inventors: Christine MENDROK-EDINGER, Alexander SCHLIFKE-POSCHALKO
  • Patent number: 10918113
    Abstract: The present disclosure describes a variant polypeptide having lipolytic activity, wherein the variant has an amino acid sequence which, when aligned with the amino acid sequence as set out in SEQ ID NO: 2, comprises at least one substitution of an amino acid residue at a position corresponding to any of the positions 53, 112, 141, 178, 179, 182, 202, 203, 235, 282, 284, said positions being defined with reference to SEQ ID NO: 2, and wherein said variant has at least 70% identity with the mature polypeptide having lipolytic activity as set out in SEQ ID NO: 2. Such a variant polypeptide may be used in the preparation of a baked product.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: February 16, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Rene Marcel De Jong, Chantal Christis, Neil Carr
  • Patent number: 10920207
    Abstract: The invention relates to a host cell comprising at least four different heterologous polynucleotides chose from the group of polynucleotides encoding cellulases, hemicellulases and pectinases, wherein the host cell is capable of producing the at least four different enzymes chosen from the group of cellulases, hemicellulases and pectinases, wherein the host cell is a filam-tous fungus and is capable of secretion of the at least four different enzymes. This host cell can suitably be used for the production of an enzyme composition that can be use in a process for the saccharification of cellulosic material.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: February 16, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Alrik Pieter Los, Cornelis Maria Jacobus Sagt, Margot Elisabeth Francoise Schooneveld-Bergmans, Robbertus Antonius Damveld
  • Patent number: 10920026
    Abstract: The present invention relates to a polymer composition, consisting of (A) 30-90 wt. % of at least one thermoplastic polymer comprising at least a semi-crystalline semi-aromatic polyamide (SSPA-1) in an amount in the range of 30-90 wt. %; (B) 10-70 wt. % of at least one reinforcing agent, and (C) 0-25 wt. % of one or more other components; wherein the SSPA-1 consists of (A-1-a) 90-100 wt. % of repeat units derived from (i) an aromatic dicarboxylic acid and (ii) diamines, and (A-1-b) 0-10 wt. % of repeat units derived from other monomers; the diamines (ii) consist of 80-95 mole % of a linear aliphatic diamine, 5-20 mole % of 2-methyl-pentamethylene diamine, and 0-10 mole % of other diamines; and the SSPA-1 has a melting temperature (Tm) of at least 300° C. The invention further relates to a molded part made of the composition, a process for making the composition and a process for making the molded part.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: February 16, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventor: Zhujuan Wang
  • Patent number: 10913859
    Abstract: The invention relates to thermosetting powder coating compositions as disclosed herein, said compositions comprising one or more unsaturated resins comprising ethylenic unsaturations, one or more curing agents, and one or more thermal radical initiators, wherein at least one of the initiators is a peroxydicarbonate-X. The invention further relates to a process for making said thermosetting powder coating compositions and processes for coating an article with said thermosetting powder coating compositions. The invention further relates to cured thermosetting powder coating compositions obtained by curing of the thermosetting powder coating compositions of the invention. The invention further relates to an article having coated thereon said thermosetting powder coating composition as well as to an article having coated and cured thereon said thermosetting powder coating composition.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: February 9, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Johannes Gertrudis Christianus Bongaerts, Dragos Popescu
  • Patent number: 10913965
    Abstract: The present disclosure relates to a novel method, expression vectors, and host cells for producing nicotinamide riboside by regulating the pathways that lead to the production of nicotinamide riboside.
    Type: Grant
    Filed: November 14, 2016
    Date of Patent: February 9, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Adam G. Lawrence, Celine ViArouge