Patents Assigned to DSM IP ASSETS
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Publication number: 20170088564Abstract: Silicone containing reactive monomers with hydrophilic end-groups of formula I useful in the manufacture of biocompatible medical devices are disclosed, wherein R1 is H or CH3, a is 0 or 1, p is an integer from 1 to 6, q is an integer from 1 to 3 and for each q, the end groups R51, R52, R53 are independently an alkyl, alkyl ether, urethane, trimethylsiloxy group, or a substituted or non-substituted aromatic group and at least one of them has a hydrophilic group Z attached wherein said hydrophilic group Z is selected from the group of poly(ethylene glycol), poly(propylene glycol), poly(ethyl oxazoline), poly(methyl oxazoline), hyaluronic acid, or combinations thereof, preferably to the terminal end of R51, R52, R53, X is O or NR54, where R54 is H or a monovalent alkyl group with 1 to 4 carbons, n is an integer from 1 to 100, R2 and R3 is independently an alkyl, alkyl ether, trimethylsiloxy group, or a substituted or non-substituted aromatic group, preferred R2 and R3 include methyl, ethyl, trimethylsiloxyType: ApplicationFiled: September 25, 2015Publication date: March 30, 2017Applicant: DSM IP ASSETS B.V.Inventors: Ananth IYER, Aziza SAHIN
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Patent number: 9603932Abstract: Intravaginal drug delivery device comprising at least one pharmaceutically active substance, and a polyurethane copolymer, wherein the copolymer has the structure according to formula (I): Also, method comprising administering one or more pharmaceutically active substances to a patient in need thereof.Type: GrantFiled: January 12, 2016Date of Patent: March 28, 2017Assignee: DSM IP ASSETS, B.V.Inventors: Robert S. Ward, Shanger Wang, Li Li, Durgaprasad Chalasani, Patrick Kiser, Meredith Roberts Clark
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Patent number: 9605156Abstract: The invention relates to a coating composition comprising an inorganic oxide precursor AMOx based on at least one inorganic element A selected from the group consisting of aluminum, silicium, titanium, zirconium, niobium, indium, tin, antimony, tantalum, and bismuth; and an inorganic oxide precursor BMOx based on at least one inorganic element B selected from the group consisting of scandium, yttrium, lanthanum, and the lanthanoids; wherein AMOx and BMOx are capable of forming a mixed inorganic oxide. A coating made from this composition shows enhanced resistance to hydrolysis. The invention also relates to a process for applying a coating on a substrate using such composition, more specifically to a liquid coating composition for use in a process of applying an anti-reflective coating on transparent substrate; to a coated substrate obtained with such process, and to an article, like a solar panel, comprising such coated substrate.Type: GrantFiled: June 17, 2011Date of Patent: March 28, 2017Assignee: DSM IP ASSETS B.V.Inventors: Nanning Joerg Arfsten, Roberto Arnoldus Dominicus Maria Habets, Pascal Jozef Paul Buskens
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Publication number: 20170081651Abstract: The present invention relates to a polypeptide having proline-specific endoprotease activity, selected from the group consisting of i. a polypeptide comprising a mature polypeptide sequence of SEQ ID NO: 2; ii. a polypeptide that has least 70%, 75%, 80%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98% or 99% identity to the mature polypeptide sequence of SEQ ID NO: 2; iii. a polypeptide encoded by a nucleic acid that hybridizes under medium stringency, preferably under high stringency conditions to the complementary strand of the mature polypeptide coding sequence of SEQ ID NO:1; iv. a polypeptide encoded by a nucleic acid that has at least 70%, 75% 80%, 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99% or 100% identity to the mature polypeptide coding sequence of SEQ ID NO: 1. The invention further relates to a method of producing the polypeptide and a process for the preparation of a food or feed product wherein the polypeptide is used.Type: ApplicationFiled: May 19, 2015Publication date: March 23, 2017Applicant: DSM IP ASSETS B.V.Inventors: Jan Metske VAN DER LAAN, Peter Jozef Ida VAN DE VONDERVOORT, Chantal CHRISTIS, Martine SPAANS, Angela DE BRUINE-PAULUS, Johanna Henrica Gerdina Maria MUTSAERS
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Patent number: 9596878Abstract: The present invention relates to the use of canthaxanthin and at least one vitamin D metabolite, preferably 25-hydroxy vitamin D3 (25-OH D3), for improving internal egg quality. Interior egg quality, usually expressed in Haugh Units, is prolonged by feeding the laying poultry a diet containing canthaxanthin and 25-hydroxy vitamin D3.Type: GrantFiled: June 10, 2014Date of Patent: March 21, 2017Assignee: DSM IP ASSETS B.V.Inventors: Isaac Bittar, Rafael Gustavo Hermes, Catherine Hamelin, Fernando Cisneros
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Patent number: 9593158Abstract: The present invention relates to a process for preparing gelatin comprising a step of incubating a material comprising collagen with an enzyme composition comprising an acid protease which has at least 70% identity to the amino acid sequence of SEQ ID NO:1, and preparing the gelatin. The invention also relates to gelatin obtained by a process as disclosed herein.Type: GrantFiled: September 16, 2013Date of Patent: March 14, 2017Assignee: DSM IP ASSETS B.V.Inventors: Zhong-Hua Quan, Monica Diana Vlasie
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Patent number: 9585837Abstract: The present invention relates to thermally, stable oil-in-water emulsions comprising an oil comprising a polyunsaturated fatty acid, water, an emulsifier, and a water-soluble stabilizer, and processes for preparing the thermally stable oil-in-water emulsions. The thermally stable oil-in-water emulsions remain flowable at a temperature of ?40° C., and are free from a variation in particle size after 9 months in storage at a temperature of ?40° C. to ?15° C.Type: GrantFiled: April 6, 2011Date of Patent: March 7, 2017Assignee: DSM IP ASSETS B.V.Inventors: Jimbin Mai, Micah Hazzy Needham, Gang Su, Wei Wang-Nolan, Chia-Ping Charles Hsu
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Patent number: 9580620Abstract: An aqueous emulsion coating composition comprising an autoxidisable vinyl oligomer having ?20 wt % of unsaturated fatty acid residue; Tg from ?50 to +15° C.; Mw from 2,500 to 40,000 g/mol; polydispersity from 2 to 12, said composition having ?15% co-solvent by weight of solids, ?13% NMP by weight of solids ?38% solids by weight of composition; said composition when in the form of a coating having a telegraphing value defined as the difference in gloss at a 20° angle of between a film cast on rough PVC and a film cast on smooth PVC of 10 gloss units.Type: GrantFiled: September 4, 2013Date of Patent: February 28, 2017Assignee: DSM IP ASSETS B.V.Inventors: Ilse Van Casteren, Gerardus Cornelis Overbeek, Ronald Tennebroek
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Patent number: 9579301Abstract: The present invention relates to an emulsion of an oil composition comprising docasoahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), which is characterized in that the emulsion is essentially free from ascorbyl palmitate.Type: GrantFiled: January 11, 2013Date of Patent: February 28, 2017Assignee: DSM IP ASSETS B.V.Inventors: Karl Manfred Voelker, Denis Hug, Thomas Lindemann
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Patent number: 9579303Abstract: The disclosure relates to compositions, preferably in the form of a powder and/or granules, which contain as principal components a first component selected from the group consisting of isoflavones, soy products containing at least one isoflavone, and mixtures thereof, together with a polysaccharide as second component. A preferred first component is genistein or a pharmaceutically acceptable salt or derivative thereof (e.g. genistin). A preferred second component is pectin. The disclosure further relates to a process for the manufacture of such compositions, and their use in dietary supplements, pharmaceutical and personal care compositions. The disclosure is also directed to the use of a polysaccharide for improving the flowability of a component selected from the group consisting of isoflavones, soy products, preferably those containing at least one isoflavone, and mixtures thereof.Type: GrantFiled: February 14, 2006Date of Patent: February 28, 2017Assignee: DSM IP ASSETS B.V.Inventors: Chyi-Cheng Chen, Bruno H. Leuenberger
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Patent number: 9574105Abstract: An aqueous solution coating composition comprising an autoxidizable polyvinyl polymer having ?20% of fatty acid residue by weight of polymer; Tg from ?60 to +15° C.; acid value of 15 to 75 mg KOH/g, Mw from 2500 to 100000 g/mol; polydispersity ?30, said composition having ?25% co-solvent by weight of solids, ?30% solids by weight of composition; said composition when in the form of a coating having a telegraphing value defined as the difference in gloss at a 20° angle of between a film cast on rough PVC and a film cast on smooth PVC of 10 gloss units.Type: GrantFiled: September 3, 2013Date of Patent: February 21, 2017Assignee: DSM IP ASSETS B.V.Inventors: Ilse Van Casteren, Gerardus Cornelis Overbeek, Ronald Tennebroek, Tijs Nabuurs, Richard George Coogan
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Patent number: 9573872Abstract: The present invention relates to a process of manufacturing compound having stereogenic centers from a mixture of E/Z isomers of unsaturated compounds having prochiral double bonds. The hydrogenation product has a specific desired configuration at the stereogenic centers. The process involves an asymmetric hydrogenation and an isomerization step. The process is very advantageous in that it forms the desired chiral product from a mixture of stereoisomers of the starting product in an efficient way.Type: GrantFiled: December 18, 2013Date of Patent: February 21, 2017Assignee: DSM IP ASSETS B.V.Inventors: Werner Bonrath, Thomas Netscher, Jonathan Alan Medlock, René Tobias Stemmler, Gerardus Karel Maria Verzijl, Andreas Hendrikus Maria De Vries
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Patent number: 9567286Abstract: The present invention relates to the use of specific organic compounds as flavor and fragrance material. Furthermore the invention relates to new specific organic compounds, as well as to flavor and fragrance formulations comprising at least one of the specific organic compounds.Type: GrantFiled: October 7, 2013Date of Patent: February 14, 2017Assignee: DSM IP ASSETS B.V.Inventors: Raphael Beumer, Johannes Tschumi, Michael Gressly
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Patent number: 9567434Abstract: A process for preparation of a polyamide PA-4X containing monomer units of 1,4-diaminobutane and an aliphatic linear dicarboxylic acid X with at least 8 carbon atoms, which contains the following steps: 1) making a solution comprising a salt of 1,4-diaminobutane and the aliphatic linear dicarboxylic acid and water, at a temperature at which the salt dissolves; 2) concentrating the solution of the salt at a temperature above the crystallization temperature of the salt, at a pressure of at most 7 barA to a water content of between 0 and 30 wt % based on the total amount of solution, 3) producing a polymer from the solution obtained by step 2, while keeping the polymer in a melt and at a pressure of less than 18 barA, 4) depressurizing the polymer obtained at step 3 while keeping the polymer in the melt to further polymerize the polymer. In an preferred embodiment the aliphatic linear dicarboxylic acid is 1,10-decanedioic acid.Type: GrantFiled: May 5, 2011Date of Patent: February 14, 2017Assignee: DSM IP ASSETS B.V.Inventors: Pim Gerard Anton Janssen, Ronald Ligthart
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Patent number: 9567476Abstract: There is disclosed a process for obtaining a water-borne crosslinkable composition comprising a block copolymer comprising at least blocks [A]x[B]y (where x is an integer from 3 to 80 (inc.), where y is an integer ?10 and where y>x) and a polymer P, the block copolymer-polymer having an acid value ?150 mg KOH per g of block copolymer-polymer, where at least block [A] and [B] is obtained by a controlled radical polymerisation of at least one ethylenically unsaturated monomer via a reversible addition-fragmentation chain transfer (RAFT) mechanism in solution in the presence of a control agent and a source of free radicals; and where polymer P is obtained in the presence of blocks [A]x[B]y by an emulsion polymerisation process.Type: GrantFiled: February 4, 2013Date of Patent: February 14, 2017Assignee: DSM IP ASSETS B.V.Inventors: Michael Arnoldus Jacobus Schellekens, Tijs Nabuurs, John Geurts, Gerardus Cornslis Overbeek
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Patent number: 9561170Abstract: The invention relates to a hair care composition comprising at least one cationic film forming polymer selected from the group of Polyquaternium and at least one quaternized hyperbranched polymer having end-groups of formula (I) characterized in that said quaternized hyperbranched polymer is obtainable by preparation of a hyperbranched polymer having dimethylamino end groups by condensation of 2-dodecen-1-ylsuccinic anhydride, diisopropanolamine and N,N-bis[3-(dimethylamino)propyl]amine followed by quaternization of the dimethylamino end-groups to end groups of formula (I).Type: GrantFiled: September 11, 2013Date of Patent: February 7, 2017Assignee: DSM IP ASSETS B.V.Inventors: Robin Elisabeth Maria Jacobus Daenen, Franciscus Johannes Marie Derks, Dirk Weber, Ruediger Wilz
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Patent number: 9561525Abstract: The present invention relates to a process for depositing an anti-reflective layer on a transparent flat substrate comprising the steps of providing a liquid coating composition comprising at least one solvent, at least one inorganic oxide precursor, and at least one pore forming agent; applying the coating composition to the substrate; drying the applied coating layer, and curing the coating layer; wherein during drying a gas flow is provided to the substrate at a flow rate of between 0.2 and 6 m/s. The advantage of this process is that defects visible in edge areas of the coated substrate can be significantly reduced.Type: GrantFiled: February 6, 2012Date of Patent: February 7, 2017Assignee: DSM IP ASSETS B.V.Inventors: Gerardus Aben, Ronnie Bernardus Maria De Rijk, Patrick Wilhelmus Antonius Vrijaldenhoven
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Patent number: 9561989Abstract: The present invention relates to a process of the asymmetric hydrogenation of a ketal of an unsaturated ketone or an acetal of an unsaturated aldehyde by molecular hydrogen in the presence of at least one chiral iridium complex. This process yields chiral compounds in a very efficient way and is very advantageous in that the amount of iridium complex can be remarkably reduced.Type: GrantFiled: December 18, 2013Date of Patent: February 7, 2017Assignee: DSM IP ASSETS B.V.Inventors: Werner Bonrath, Thomas Netscher, Jonathan Alan Medlock, Gerardus Karel Maria Verzijl, Andreas Hendrikus Maria De Vries
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Patent number: 9561993Abstract: The invention relates to a process for the manufacture of substituted dibenzoylmethane derivatives. This economical process provides products in high purity and yields and results in shorter reaction times.Type: GrantFiled: December 19, 2011Date of Patent: February 7, 2017Assignee: DSM IP ASSETS B.V.Inventor: Christof Wehrli
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Publication number: 20170029476Abstract: The present invention relates to a nucleic acid construct comprising: a nucleic acid sequence encoding an ice structuring protein (ISP) comprising the sequence set out in SEQ ID NO: 1 or a sequence at least 80% identical thereto or comprising the sequence set out in amino acids 21 to 261 of SEQ ID NO: 1 or a sequence at least 80% identical thereto; and, linked operably thereto, control sequences permitting expression of the nucleic acid sequence in a filamentous fungal host cell. The construct may be used in a method for the production of an ISP, wherein the ISP is expressed in a filamentous fungal host cell.Type: ApplicationFiled: December 2, 2014Publication date: February 2, 2017Applicant: DSM IP ASSETS B.V.Inventors: René Marcel DE JONG, Petrus Jacobus THEODORUS