Patents Assigned to DSM Nutritional Products
  • Patent number: 11883422
    Abstract: Preparations of glycan therapeutics, pharmaceutical compositions, dietary supplements and medical foods thereof are provided, and methods of using said glycan therapeutics, e.g. in cancer therapy.
    Type: Grant
    Filed: June 30, 2021
    Date of Patent: January 30, 2024
    Assignee: DSM Nutritional Products, LLC
    Inventors: Geoffrey A. von Maltzahn, Yvonne J. Yamanaka, Jared Silverman, John Miles Milwid, Jacob Rosenblum Rubens, John M. Geremia
  • Patent number: 11697692
    Abstract: Preparations of glycan polymers and variations thereof, pharmaceutical compositions, medical foods, supplements, foods, food ingredients, feed ingredients, and feed additives thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same.
    Type: Grant
    Filed: November 3, 2018
    Date of Patent: July 11, 2023
    Assignee: DSM Nutritional Products, LLC
    Inventors: John M. Geremia, Christopher Matthew Liu, Anastasia V. Lioubomirov
  • Patent number: 11653676
    Abstract: Described herein are methods of producing animal feed made up of oligosaccharide compositions, as well as methods of producing such oligosaccharide compositions and animal feed compositions, and methods of using such animal feed compositions to enhance animal growth.
    Type: Grant
    Filed: November 30, 2020
    Date of Patent: May 23, 2023
    Assignee: DSM Nutritional Products, LLC
    Inventors: John M. Geremia, Raffi Mardirosian, Michael J. Gidding, Anastasia V. Murphy
  • Patent number: 11649473
    Abstract: The disclosed subject matter relates generally to a method for modifying oil, and specifically to a process for increasing the concentration of polyunsaturated fatty acid in an oil composition.
    Type: Grant
    Filed: July 29, 2019
    Date of Patent: May 16, 2023
    Assignee: DSM Nutritional Products AG
    Inventors: Jaroslav A. Kralovec, Weijie Wang, James Colin Barrow
  • Patent number: 11584805
    Abstract: Described herein are methods for the production of oligosaccharides, including functionalized oligosaccharides, from one or more sugars, such as one or more monosaccharides, using polymeric and solid-supported catalysts containing acidic and ionic groups. Also provided are the oligosaccharide compositions, including functionalized oligosaccharide compositions, obtained using the methods.
    Type: Grant
    Filed: June 25, 2020
    Date of Patent: February 21, 2023
    Assignee: DSM Nutritional Products, LLC
    Inventors: John M. Geremia, Anastasia V. Lioubomirov, Scott Han, Benjamin A. Seigal, Alicia Landry, Kyle Sherry, Stephen Panos, Devin Churchman, Andrew O'Connor
  • Patent number: 11001782
    Abstract: Provided herein are methods of recovering oil from microorganisms. The methods are useful, for example, in obtaining nutritional oils and/or lipid biofuels. The methods of recovering oil described herein include contacting a population of microorganisms with one or more enzymes under conditions that cause disruption of the microorganisms and extracting lipids from the population of microorganisms in the presence of reduced amounts of organic solvent or in the absence of organic solvent.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: May 11, 2021
    Assignee: DSM Nutritional Products AG
    Inventors: Dorothy A. Dennis, Roberto E. Armenta
  • Patent number: 10435725
    Abstract: Disclosed are compositions and methods related to eukaryotic microorganisms that can produce unsaturated fatty acids which can be purified and used.
    Type: Grant
    Filed: June 21, 2017
    Date of Patent: October 8, 2019
    Assignee: DSM NUTRITIONAL PRODUCTS AG
    Inventors: Adam M. Burja, Helia Radianingtyas, Colin James Barrow, Anthony James Windust
  • Publication number: 20190169660
    Abstract: Disclosed are compositions and methods related to eukaryotic microorganisms that can produce unsaturated fatty acids which can be purified and used.
    Type: Application
    Filed: September 17, 2018
    Publication date: June 6, 2019
    Applicant: DSM NUTRITIONAL PRODUCTS AG
    Inventors: Adam M BURJA, Helia RADIANINGTYAS, Colin James BARROW, Anthony James WINDUST
  • Patent number: 10166196
    Abstract: Disclosed are microcapsules with shells that are not animal by-products and methods for preparing and using such microcapsules.
    Type: Grant
    Filed: January 9, 2008
    Date of Patent: January 1, 2019
    Assignee: DSM NUTRITIONAL PRODUCTS AG
    Inventors: Cuie Yan, Wei Zhang, Yulai Jin, Lesek Alexa Demont, Colin James Barrow
  • Patent number: 9968120
    Abstract: Disclosed are homogenized formulations that comprise microcapsules, wherein the microcapsules comprise an agglomeration of primary microcapsules and a loading substance, where each individual primary microcapsule has a primary shell, and the loading substance is encapsulated by the primary shell, and wherein the agglomeration is encapsulated by an outer shell. Also, disclosed are methods of making and using homogenized formulations by providing a pre-homogenized composition comprising one or more microcapsules and then homogenizing the composition. Some specific homogenization processes described are ultrasonic and pressure-based homogenizations.
    Type: Grant
    Filed: May 17, 2006
    Date of Patent: May 15, 2018
    Assignee: DSM NUTRITIONAL PRODUCTS AG
    Inventors: Jonathan Michael Curtis, Wei Zhang, Sharon Ann Spurvey, Suzelle Rejeanne Robert
  • Patent number: 9873880
    Abstract: Provided are Thraustochytrid and Thraustochytrium and relevant methods and reagents, including engineered regulatory sequences and genes from and/or operative in Thraustochytrid or Thraustochytrium, selectable markers useful for engineering microorganisms such as Thraustochytrids, means for mutagenizing microorganisms, strains produced by mutagenesis, and methods and compositions related to production of particular compounds in microorganisms.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: January 23, 2018
    Assignee: DSM Nutritional Products AG
    Inventors: Mark A. Scaife, Roberto E. Armenta
  • Publication number: 20170335356
    Abstract: Disclosed are compositions and methods related to eukaryotic microorganisms that can produce unsaturated fatty acids which can be purified and used.
    Type: Application
    Filed: June 21, 2017
    Publication date: November 23, 2017
    Applicant: DSM NUTRITIONAL PRODUCTS AG
    Inventors: Adam M. Burja, Helia Radianingtyas, Colin James Barrow, Anthony James Windust
  • Patent number: 9758787
    Abstract: The present disclosure provides, inter alia, Thraustochytrium and relevant methods and reagents, including engineered regulatory sequences from and/or operative in Thraustochytrid or Thraustochytrium, selectable markers useful for engineering microorganisms such as Thraustochytrids, means for mutagenizing microorganisms, novel strains produced by mutagenesis, and methods and compositions related to production of particular compounds in microorganisms.
    Type: Grant
    Filed: August 4, 2015
    Date of Patent: September 12, 2017
    Assignee: DSM NUTRITIONAL PRODUCTS AG
    Inventors: ShuoCheng Zhang, Roberto E. Armenta
  • Patent number: 9725408
    Abstract: Disclosed are methods of recovering urea from a urea/oil complex by drying the complex, combining the complex with water to form a urea solution, and removing water from the urea solution. Methods for recycling the urea in urea complexation processes are also disclosed. Also disclosed are methods of recovering polyunsaturated fatty acids or derivatives thereof from the urea/oil complexes.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: August 8, 2017
    Assignee: DSM Nutritional Products AG
    Inventors: Weijie Wang, Paul Frederick Mugford, Theophilus Cornelus Van Den Heuvel
  • Publication number: 20160312147
    Abstract: Provided herein are methods of recovering oil from microorganisms. The methods are useful, for example, in obtaining nutritional oils and/or lipid biofuels. The methods of recovering oil described herein include contacting a population of microorganisms with one or more enzymes under conditions that cause disruption of the microorganisms and extracting lipids from the population of microorganisms in the presence of reduced amounts of organic solvent or in the absence of organic solvent.
    Type: Application
    Filed: December 19, 2014
    Publication date: October 27, 2016
    Applicant: DSM NUTRITIONAL PRODUCTS AG
    Inventors: Dorothy A. Dennis, Roberto E. Armenta
  • Patent number: 9441212
    Abstract: Disclosed are methods and compositions related to ONC-T18, D4-desaturases, D5 elongases, their isolation, characterization, production, identification, and use for fatty acid production, as well as organisms containing these compositions and organisms expressing them.
    Type: Grant
    Filed: May 6, 2014
    Date of Patent: September 13, 2016
    Assignee: DSM NUTRITIONAL PRODUCTS AG
    Inventors: Adam M. Burja, Gabrielle S. Chafe, Helia Radianingtyas
  • Patent number: 9133463
    Abstract: The present disclosure provides, inter alia, Thraustochytrium and relevant methods and reagents, including engineered regulatory sequences from and/or operative in Thraustochytrid or Thraustochytrium, selectable markers useful for engineering microorganisms such as Thraustochytrids, methods for mutagenizing microorganisms, novel strains produced by mutagenesis and methods and compositions related to production of particular compounds in microorganisms.
    Type: Grant
    Filed: March 7, 2012
    Date of Patent: September 15, 2015
    Assignee: DSM NUTRITIONAL PRODUCTS AG
    Inventors: ShuoCheng Zhang, Roberto Armenta
  • Patent number: 9056058
    Abstract: Disclosed are microcapsules and methods for preparing and using them, as well as methods for improving various properties of microcapsules like impermeability.
    Type: Grant
    Filed: June 4, 2007
    Date of Patent: June 16, 2015
    Assignee: DSM Nutritional Products
    Inventors: Jin Yulai, Colin James Barrow, Wei Zhang, Cuie Yan, Jonathan Michael Curtis, Shawn Moulton, Nancy Beatrice Djogbenou, Lesek Alexa Demont
  • Patent number: 9023616
    Abstract: Disclosed are compositions and methods related to a eukaryote of the order Thraustochytriales and family Thraustochytriaceae which when cultured produce quantities of unsaturated fatty acids, such as omega 3 (n-3) and/or omega 6 (n-6) oils, such as DHA, EPA and DPA, capable of being purified and used as all such compositions are used and more, because of their means of production.
    Type: Grant
    Filed: July 30, 2007
    Date of Patent: May 5, 2015
    Assignee: DSM Nutritional Products AG
    Inventors: Helia Radianingtyas, Adam M. Burja, James Colin Barrow
  • Patent number: 8968872
    Abstract: Microcapsules comprising an agglomeration of primary microcapsules, each individual primary microcapsule having a primary shell and the agglomeration being encapsulated by an outer shell, may be prepared by providing an aqueous mixture of a loading substance and a shell material, adjusting pH, temperature, concentration and/or mixing speed to form primary shells of shell material around the loading substance and cooling the aqueous mixture until the primary shells agglomerate and an outer shell of shell material forms around the agglomeration. Such microcapsules are useful for storing a substance and for delivering the substance to a desired environment.
    Type: Grant
    Filed: April 27, 2010
    Date of Patent: March 3, 2015
    Assignee: DSM Nutritional Products AG
    Inventor: Nianxi Yan