Patents Assigned to DSM Nutritional Products
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Patent number: 11883422Abstract: Preparations of glycan therapeutics, pharmaceutical compositions, dietary supplements and medical foods thereof are provided, and methods of using said glycan therapeutics, e.g. in cancer therapy.Type: GrantFiled: June 30, 2021Date of Patent: January 30, 2024Assignee: DSM Nutritional Products, LLCInventors: Geoffrey A. von Maltzahn, Yvonne J. Yamanaka, Jared Silverman, John Miles Milwid, Jacob Rosenblum Rubens, John M. Geremia
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Patent number: 11697692Abstract: Preparations of glycan polymers and variations thereof, pharmaceutical compositions, medical foods, supplements, foods, food ingredients, feed ingredients, and feed additives thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same.Type: GrantFiled: November 3, 2018Date of Patent: July 11, 2023Assignee: DSM Nutritional Products, LLCInventors: John M. Geremia, Christopher Matthew Liu, Anastasia V. Lioubomirov
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Patent number: 11653676Abstract: Described herein are methods of producing animal feed made up of oligosaccharide compositions, as well as methods of producing such oligosaccharide compositions and animal feed compositions, and methods of using such animal feed compositions to enhance animal growth.Type: GrantFiled: November 30, 2020Date of Patent: May 23, 2023Assignee: DSM Nutritional Products, LLCInventors: John M. Geremia, Raffi Mardirosian, Michael J. Gidding, Anastasia V. Murphy
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Patent number: 11649473Abstract: The disclosed subject matter relates generally to a method for modifying oil, and specifically to a process for increasing the concentration of polyunsaturated fatty acid in an oil composition.Type: GrantFiled: July 29, 2019Date of Patent: May 16, 2023Assignee: DSM Nutritional Products AGInventors: Jaroslav A. Kralovec, Weijie Wang, James Colin Barrow
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Patent number: 11584805Abstract: Described herein are methods for the production of oligosaccharides, including functionalized oligosaccharides, from one or more sugars, such as one or more monosaccharides, using polymeric and solid-supported catalysts containing acidic and ionic groups. Also provided are the oligosaccharide compositions, including functionalized oligosaccharide compositions, obtained using the methods.Type: GrantFiled: June 25, 2020Date of Patent: February 21, 2023Assignee: DSM Nutritional Products, LLCInventors: John M. Geremia, Anastasia V. Lioubomirov, Scott Han, Benjamin A. Seigal, Alicia Landry, Kyle Sherry, Stephen Panos, Devin Churchman, Andrew O'Connor
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Patent number: 11001782Abstract: Provided herein are methods of recovering oil from microorganisms. The methods are useful, for example, in obtaining nutritional oils and/or lipid biofuels. The methods of recovering oil described herein include contacting a population of microorganisms with one or more enzymes under conditions that cause disruption of the microorganisms and extracting lipids from the population of microorganisms in the presence of reduced amounts of organic solvent or in the absence of organic solvent.Type: GrantFiled: December 19, 2014Date of Patent: May 11, 2021Assignee: DSM Nutritional Products AGInventors: Dorothy A. Dennis, Roberto E. Armenta
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Patent number: 10435725Abstract: Disclosed are compositions and methods related to eukaryotic microorganisms that can produce unsaturated fatty acids which can be purified and used.Type: GrantFiled: June 21, 2017Date of Patent: October 8, 2019Assignee: DSM NUTRITIONAL PRODUCTS AGInventors: Adam M. Burja, Helia Radianingtyas, Colin James Barrow, Anthony James Windust
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Publication number: 20190169660Abstract: Disclosed are compositions and methods related to eukaryotic microorganisms that can produce unsaturated fatty acids which can be purified and used.Type: ApplicationFiled: September 17, 2018Publication date: June 6, 2019Applicant: DSM NUTRITIONAL PRODUCTS AGInventors: Adam M BURJA, Helia RADIANINGTYAS, Colin James BARROW, Anthony James WINDUST
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Patent number: 10166196Abstract: Disclosed are microcapsules with shells that are not animal by-products and methods for preparing and using such microcapsules.Type: GrantFiled: January 9, 2008Date of Patent: January 1, 2019Assignee: DSM NUTRITIONAL PRODUCTS AGInventors: Cuie Yan, Wei Zhang, Yulai Jin, Lesek Alexa Demont, Colin James Barrow
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Patent number: 9968120Abstract: Disclosed are homogenized formulations that comprise microcapsules, wherein the microcapsules comprise an agglomeration of primary microcapsules and a loading substance, where each individual primary microcapsule has a primary shell, and the loading substance is encapsulated by the primary shell, and wherein the agglomeration is encapsulated by an outer shell. Also, disclosed are methods of making and using homogenized formulations by providing a pre-homogenized composition comprising one or more microcapsules and then homogenizing the composition. Some specific homogenization processes described are ultrasonic and pressure-based homogenizations.Type: GrantFiled: May 17, 2006Date of Patent: May 15, 2018Assignee: DSM NUTRITIONAL PRODUCTS AGInventors: Jonathan Michael Curtis, Wei Zhang, Sharon Ann Spurvey, Suzelle Rejeanne Robert
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Patent number: 9873880Abstract: Provided are Thraustochytrid and Thraustochytrium and relevant methods and reagents, including engineered regulatory sequences and genes from and/or operative in Thraustochytrid or Thraustochytrium, selectable markers useful for engineering microorganisms such as Thraustochytrids, means for mutagenizing microorganisms, strains produced by mutagenesis, and methods and compositions related to production of particular compounds in microorganisms.Type: GrantFiled: March 12, 2014Date of Patent: January 23, 2018Assignee: DSM Nutritional Products AGInventors: Mark A. Scaife, Roberto E. Armenta
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Publication number: 20170335356Abstract: Disclosed are compositions and methods related to eukaryotic microorganisms that can produce unsaturated fatty acids which can be purified and used.Type: ApplicationFiled: June 21, 2017Publication date: November 23, 2017Applicant: DSM NUTRITIONAL PRODUCTS AGInventors: Adam M. Burja, Helia Radianingtyas, Colin James Barrow, Anthony James Windust
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Patent number: 9758787Abstract: The present disclosure provides, inter alia, Thraustochytrium and relevant methods and reagents, including engineered regulatory sequences from and/or operative in Thraustochytrid or Thraustochytrium, selectable markers useful for engineering microorganisms such as Thraustochytrids, means for mutagenizing microorganisms, novel strains produced by mutagenesis, and methods and compositions related to production of particular compounds in microorganisms.Type: GrantFiled: August 4, 2015Date of Patent: September 12, 2017Assignee: DSM NUTRITIONAL PRODUCTS AGInventors: ShuoCheng Zhang, Roberto E. Armenta
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Patent number: 9725408Abstract: Disclosed are methods of recovering urea from a urea/oil complex by drying the complex, combining the complex with water to form a urea solution, and removing water from the urea solution. Methods for recycling the urea in urea complexation processes are also disclosed. Also disclosed are methods of recovering polyunsaturated fatty acids or derivatives thereof from the urea/oil complexes.Type: GrantFiled: March 13, 2014Date of Patent: August 8, 2017Assignee: DSM Nutritional Products AGInventors: Weijie Wang, Paul Frederick Mugford, Theophilus Cornelus Van Den Heuvel
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Publication number: 20160312147Abstract: Provided herein are methods of recovering oil from microorganisms. The methods are useful, for example, in obtaining nutritional oils and/or lipid biofuels. The methods of recovering oil described herein include contacting a population of microorganisms with one or more enzymes under conditions that cause disruption of the microorganisms and extracting lipids from the population of microorganisms in the presence of reduced amounts of organic solvent or in the absence of organic solvent.Type: ApplicationFiled: December 19, 2014Publication date: October 27, 2016Applicant: DSM NUTRITIONAL PRODUCTS AGInventors: Dorothy A. Dennis, Roberto E. Armenta
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Patent number: 9441212Abstract: Disclosed are methods and compositions related to ONC-T18, D4-desaturases, D5 elongases, their isolation, characterization, production, identification, and use for fatty acid production, as well as organisms containing these compositions and organisms expressing them.Type: GrantFiled: May 6, 2014Date of Patent: September 13, 2016Assignee: DSM NUTRITIONAL PRODUCTS AGInventors: Adam M. Burja, Gabrielle S. Chafe, Helia Radianingtyas
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Patent number: 9133463Abstract: The present disclosure provides, inter alia, Thraustochytrium and relevant methods and reagents, including engineered regulatory sequences from and/or operative in Thraustochytrid or Thraustochytrium, selectable markers useful for engineering microorganisms such as Thraustochytrids, methods for mutagenizing microorganisms, novel strains produced by mutagenesis and methods and compositions related to production of particular compounds in microorganisms.Type: GrantFiled: March 7, 2012Date of Patent: September 15, 2015Assignee: DSM NUTRITIONAL PRODUCTS AGInventors: ShuoCheng Zhang, Roberto Armenta
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Patent number: 9056058Abstract: Disclosed are microcapsules and methods for preparing and using them, as well as methods for improving various properties of microcapsules like impermeability.Type: GrantFiled: June 4, 2007Date of Patent: June 16, 2015Assignee: DSM Nutritional ProductsInventors: Jin Yulai, Colin James Barrow, Wei Zhang, Cuie Yan, Jonathan Michael Curtis, Shawn Moulton, Nancy Beatrice Djogbenou, Lesek Alexa Demont
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Patent number: 9023616Abstract: Disclosed are compositions and methods related to a eukaryote of the order Thraustochytriales and family Thraustochytriaceae which when cultured produce quantities of unsaturated fatty acids, such as omega 3 (n-3) and/or omega 6 (n-6) oils, such as DHA, EPA and DPA, capable of being purified and used as all such compositions are used and more, because of their means of production.Type: GrantFiled: July 30, 2007Date of Patent: May 5, 2015Assignee: DSM Nutritional Products AGInventors: Helia Radianingtyas, Adam M. Burja, James Colin Barrow
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Patent number: 8968872Abstract: Microcapsules comprising an agglomeration of primary microcapsules, each individual primary microcapsule having a primary shell and the agglomeration being encapsulated by an outer shell, may be prepared by providing an aqueous mixture of a loading substance and a shell material, adjusting pH, temperature, concentration and/or mixing speed to form primary shells of shell material around the loading substance and cooling the aqueous mixture until the primary shells agglomerate and an outer shell of shell material forms around the agglomeration. Such microcapsules are useful for storing a substance and for delivering the substance to a desired environment.Type: GrantFiled: April 27, 2010Date of Patent: March 3, 2015Assignee: DSM Nutritional Products AGInventor: Nianxi Yan