Patents Assigned to DSM
  • Publication number: 20100130695
    Abstract: The present invention relates to a polymer composition with an increased rate of oxygen-uptake by the presence of an oxidation catalyst. The invention further relates to a process to increase the rate of oxygen-uptake by a polymer composition. The invention also relates to a process to increase the oxo-biodegradability of a polymer composition and to the use of such a composition for the preparation of a product having a controlled lifetime. The invention further relates to a process to increase the rate of oxygen-scavenging in a composition containing a carbon-containing polymer, the composition obtained by this method and its use in the preparation of an oxygen-scavenging product. The present invention further relates to objects containing an oxygen scavenging layer containing such a composition.
    Type: Application
    Filed: July 4, 2007
    Publication date: May 27, 2010
    Applicant: DSM IP ASSETS B.V.
    Inventors: Pieter Gijsman, Johan Franz Gradus Antonius Jansen
  • Publication number: 20100124398
    Abstract: A Radiation Curable Coating composition, which may be used as an inner primary coating, an outer primary coating, single coats, a matrix, or a buffer resin composition, comprising: A Radiation Curable Coating composition, which may be used as an inner primary coating, an outer primary coating, single coats, a matrix, or a buffer resin composition, comprising at least one radiation-curable oligomer wherein said at least one radiation curable oligomer is a fatty-acid modified epoxy acrylate; at least one ethylenenic unsaturated reactive diluent; wherein said oligomer(s) and diluent(s) are selected from the group that does not include moieties with Urethane chemistry. This composition, when tested, is found to have resistance to thermal degradation as measured by less than 10% weight loss after exposure of cured specimens in a natural convection furnace for 100 hours at 180° C.
    Type: Application
    Filed: November 3, 2009
    Publication date: May 20, 2010
    Applicant: DSM IP ASSETS B.V.
    Inventors: Edward J. MURPHY, Timothy Bishop, Steven R. Schmid
  • Patent number: 7718205
    Abstract: The invention relates to an improved process for the preparation of calcium-D-pantothenate from fermentation broths comprising eluting D-pantothenic acid from a strongly basic anion exchange resin with a weak organic acid and neutralising the eluate with a basic calcium salt.
    Type: Grant
    Filed: April 18, 2005
    Date of Patent: May 18, 2010
    Assignee: DSM IP Assets B.V.
    Inventor: Frank Eisele
  • Patent number: 7718406
    Abstract: The invention relates to compounds of general formula (I) and acid addition salts thereof, where the various symbols have the meanings given in the description and claims, the production and use thereof as substrate for the detection of TAFIa, a fibrinolysis inhibiting enzyme. The detection occurs by using the absorption between 400 and 412 nm, arising as a result of the formation of 3-carboxy-4-nitrothiophenol from Ellman's reagent as a function of time.
    Type: Grant
    Filed: December 6, 2002
    Date of Patent: May 18, 2010
    Assignee: DSM IP Assets B.V.
    Inventors: Hugo Ziegler, Dagmar Prasa, Jörg Stürzebecher, Peter Wikstroem
  • Publication number: 20100120154
    Abstract: The present invention discloses a method to construct eukaryotic cells having a target sequence in a chromosomal DNA sequence replaced by a replacement sequence of interest comprising: modifying a parent eukaryotic cell with a preference for NHR to provide a eukaryotic cell having an increased HR/NHR ratio as compared to the parent cell, providing two sets of DNA molecules of which the first set comprises DNA molecules each comprising a first non-functional fragment of the replacement sequence of interest flanked at its 5?-side by a DNA sequence substantially homologous to a sequence of the chromosomal DNA flanking the target sequence and the second set comprises DNA molecules each comprising a second non-functional fragment of the DNA replacement sequence of interest overlapping with the first non-functional fragment and flanked at its 3?-side by a DNA sequence substantially homologous to a sequence of the chromosomal DNA flanking the target sequence, wherein the first and second non-functional fragments
    Type: Application
    Filed: March 20, 2008
    Publication date: May 13, 2010
    Applicant: DSM IP Assets B.V.
    Inventors: Hesselien Touw-Riel, Marco Alexander Berg, Van Den
  • Publication number: 20100119646
    Abstract: The present invention relates to the use of a selected group of phenol derivatives as components of animal feed or feed additives for the improvement of animal performance as well as to the corresponding animal feed or feed additives containing them.
    Type: Application
    Filed: January 31, 2008
    Publication date: May 13, 2010
    Applicant: DSM IP ASSETS B.V.
    Inventors: Daniel D'Orazio, Antoine Saizieu-De, Goede Schueler, Aurelia Seon, Carlos Simoes-Nunes
  • Patent number: 7713724
    Abstract: The invention relates to isolated polypeptides with hydantoin recemase activity, that do not suffer from substrate inhibition. Such polypeptides arc for instance isolated polypeptides with at least 87% identity with SEQ ID: NO. 2 or SEQ ED: NO. 4. The invention also relates to nucleic acid sequences encoding these polypeptides. The invention also relates to processes for the racemisation of enantiomerically enriched hydantoin compounds and to processes for the preparation of enantiomarically enriched I)-or I-? amino acids.
    Type: Grant
    Filed: May 23, 2003
    Date of Patent: May 11, 2010
    Assignee: DSM IP Assets B.V.
    Inventors: Wilhelmus Hubertus Joseph Boesten, Joannes Gerardus Theodorus Kierkels, Friso Bernard Jan Assema, Luis Miguel Ruiz Pérez, Dolores González Pacanowska, Jesús González López, Santiago De La Escalera Hueso
  • Publication number: 20100112162
    Abstract: An oil composition containing 25-hydroxy Vitamin D3 and an oil is provided. In addition an emulsion, a microencapsulated oil composition, and a feed premix composition each containing 25-hydroxy Vitamin D3 are provided. Methods of making an oil composition, a microencapsulated oil composition, and a feed premix containing 25-hydroxy Vitamin D3 are also provided.
    Type: Application
    Filed: December 4, 2009
    Publication date: May 6, 2010
    Applicant: DSM IP ASSETS B.V.
    Inventors: Jean-Claude Tritsch, Li-Qun Yu, Stephen Thomas Mazzaro
  • Publication number: 20100112635
    Abstract: A method of enzymatically producing a protein hydrolysate from a protein substrate is described, wherein a proline-specific endoprotease or a composition containing a proline-specific endoprotease and optionally a subtilisin or a metallo endoprotease, and other enzymes such as carboxypeptidases, is used to produce a protein hydrolysate enriched in peptide fragments having a carboxy-terminal proline residue. Such protein hydrolysates may be used as such or to reduce bitterness in foods nutritionally supplemented by protein hydrolysates, as well as to produce hydrolysate-containing foodstuffs having low antigenicity.
    Type: Application
    Filed: September 17, 2009
    Publication date: May 6, 2010
    Applicant: DSM IP ASSETS B.V.
    Inventors: Luppo Edens, Robertus Antonius Mijndert Hoeven, Van Der, Veronique Delest
  • Patent number: 7705109
    Abstract: Processes for the preparation of a block copolyetherester elastomer and block copolyether elastomers made thereby are provided having polyester hard blocks and poly(alkylene oxide) polyol soft blocks, wherein at least one aromatic dicarboxylic acid or an ester-forming derivative thereof, and at least one alkylene diol, are esterified with a poly(alkylene oxide) polyol, comprising an poly(propylene oxide), end capped with ethylene oxide, are esterified, an ethylene oxide content of between 22 and 90% by weight, relative to the total weight of the poly(alkylene oxide) polyol, and an unsaturation content, being the total content of vinyl and allyl groups, of less than 35 meq per kg poly(alkylene oxide) polyol.
    Type: Grant
    Filed: February 3, 2005
    Date of Patent: April 27, 2010
    Assignee: DSM IP Assets B.V.
    Inventors: Heide-Anna Götz, Angelika Schmidt, Mohamed Redoine Dahrouch, Dionisius Maria Joseph Guillaume Gilissen
  • Patent number: 7705172
    Abstract: The invention relates to a process for the production of an organometallic compound according to formula (1): MALjYrX(p.
    Type: Grant
    Filed: September 13, 2006
    Date of Patent: April 27, 2010
    Assignee: DSM IP Assets B.V.
    Inventors: Edwin Gerard Ijpeij, Martin Alexander Zuideveld, Henricus Johannes Arts, Francis Van Der Burgt, Gerardus Henricus Josephus Van Doremaele
  • Patent number: 7706659
    Abstract: The invention relates to coated optical fibers comprising soft primary coatings and to such primary coatings for protecting glass optical fibers having a sufficient high resistance against cavitation. In particular, the primary coatings have a cavitation strength at which a tenth cavitation appears (?10cav) of at least about 1.0 MPa as measured at a deformation rate of 0.20% min?1 and of at least about 1.4 times their storage modulus at 23° C. The coating preferably shows strain hardening in a relative Mooney plot, preferably has a strain energy release rate Go of about 20 J/m2 or more, and preferably has a low volumetric thermal expansion coefficient. The invention furthermore provides a method and apparatus for measuring the cavitation strength of a primary coating.
    Type: Grant
    Filed: November 9, 2005
    Date of Patent: April 27, 2010
    Assignee: DSM IP Assets B.V.
    Inventors: Markus J. H. Bulters, Gerrit Rekers, Philippe W. P. V. Bleiman, Jozef M. H. Linsen, Alexander A. M. Stroeks, Johannes A. Van Eekelen, Adrianus G. M. Abel, Marko Dorschu, Paulus A. M. Steeman
  • Patent number: 7704419
    Abstract: Process for the preparation of urea granules in a fluid bed granulator comprising at least one inlet for fluidization air, a distribution plate above which the fluid bed is present and sprayers that are mounted in the distribution plate, from which the urea melt is sprayed on or over the urea particles present in the fluid bed, which particles are kept in motion by the fluidization air, characterized in that the fluidization air contains very finely atomized water and in that the urea concentration of the urea melt is higher than 97 wt. %.
    Type: Grant
    Filed: July 2, 2004
    Date of Patent: April 27, 2010
    Assignee: DSM IP Assets B.V.
    Inventors: Stanislaus Martinus Petrus Mutsers, Antonius Jozef Peter Bongers, Gerardus Mathias Cornelis Wagemans
  • Patent number: 7704608
    Abstract: The invention relates to new processes for the preparation of antireflective coatings and coated substrates, as well as articles produced by these processes. These coatings can include one or more layers made of materials which form nano-structured and/or nano-porous surfaces. The process can include applying a cross-linkable hard coat to a substrate, partially curing or cross-linking the hard coat, and then applying a second coat carried by a solvent or mixture of solvents capable of swelling the partially cured hard coat. The second coat is then cross-linked and grafted to the hard coat to produce a durable coated substrate with antireflective properties.
    Type: Grant
    Filed: March 15, 2007
    Date of Patent: April 27, 2010
    Assignee: DSM IP Assets B.V.
    Inventors: Jens C. Thies, Edwin Currie, Guido J. W. Meijers, Keqi Gan
  • Publication number: 20100099727
    Abstract: The invention provides novel compounds of general formula I wherein R1, R2 and R3 are independently hydrogen, OR4, C1-C6 alkyl or C2-C6 alkenyl, R4 is hydrogen, C1-C6 alkyl or C2-C6 alkenyl, —N-(AA) represents the residue of an amino acid or of a peptide which is bonded over the N-terminus of the amino acid or the peptide and the peptide is composed of 2 to 6, that means 2, 3, 4, 5 or 6, amino acids, wherein the C-terminus of the amino acid or the peptide is optionally esterified with a C1-C16 hydrocarbon moiety and n is an integer of 1 to 5. The compounds are in particular useful for cosmetic applications.
    Type: Application
    Filed: November 27, 2009
    Publication date: April 22, 2010
    Applicant: DSM IP ASSETS B.V.
    Inventors: Jochen Klock, Philippe Emmandel Maillan, Juergen H. Vollhardt, Raphael Beumer
  • Publication number: 20100099753
    Abstract: The present invention refers to tricyclic diterpenes and their derivatives of the formulae (I) and (II), wherein R1 is hydrogen or C1-6-alkyl; R2 is hydroxy, C3-5-acyloxy, hydroxymethyl, 1,3-dihydroxypropyl or C1-6-alkyl; R3 and R4 independently from each other are hydrogen, hydroxy, hydroxymethyl, C1-5-acyloxy or C1-6-alkoxy; R5 is C1-6-alkyl, hydroxymethyl carboxy or methoxycarbonyl; R9 is hydrogen, hydroxymethyl, methoxy, oxo or C1-5-acyloxy; R10 is hydrogen, or R5 and R9 taken together are —CH2—O— or —O—CH2—; or R5 and R10 taken together are —CO—O—, —O—CO—, —CH2—O— or —O—CH2—; R6 is hydrogen, or R5 and R6 together form a bond; R7 and R8 independently from each other are C1-6-alkyl, carboxy, x-hydroxy-Cx-alkyl (with x being an integer from 1 to 6), or C1-6-alkoxycarbonyl with the proviso that at least one of R7 and R8 is C1-6-alkyl; R11 and R12 are both hydrogen or R11 and R12 together are oxo, with the further proviso for formula (I) that if R2 is hydroxy R1 is C1-6-alkyl, for use as medicaments for the t
    Type: Application
    Filed: December 23, 2009
    Publication date: April 22, 2010
    Applicant: DSM IP ASSETS B.V.
    Inventors: Antoine De Saizieu, Ann Fowler, Regina Goralczyk, Claus Kilpert, Goede Schueler, Christof Wehrli
  • Patent number: 7700723
    Abstract: The present invention discloses an isolated polynucleotide molecule derived from a polynucleotide encoding a polypeptide having L-sorbosone dehydrogenase activity comprising a partial nucleotide sequence of at least 20 consecutive nucleotides of SEQ ID NO:1. The present invention further relates to a process for the production of L-ascorbic acid in high yield, in particular a process using resting cells of a microorganism able to convert given carbon sources into vitamin C. The thus obtained vitamin C may be further processed by purification and/or separation steps.
    Type: Grant
    Filed: August 16, 2004
    Date of Patent: April 20, 2010
    Assignee: DSM IP Assets B.V.
    Inventors: Alan Berry, Connie Lee, Anne Françoise Mayer, Masako Shinjoh
  • Patent number: 7700012
    Abstract: Process for the production of urea-comprising particles, wherein the urea-comprising particles are produced in a pelletizer, comprising a feeding device, a belt and a device to remove the formed pellets from the belt, by feeding a urea-comprising liquid to the feeding device from which droplets of the urea-comprising liquid are dosed to the belt, whereon the urea-comprising droplets solidify and cool to a temperature of ?55° C., whereafter the formed urea-comprising particles are removed from the belt.
    Type: Grant
    Filed: April 3, 2006
    Date of Patent: April 20, 2010
    Assignee: DSM IP Assets B.V.
    Inventors: Jan Wiebe J. W. Van Der Werf, Marc Jozeph M. J. Brouwer
  • Patent number: 7696364
    Abstract: The present invention relates to a process for the manufacture of alkenylated aromatic compounds featuring at least one hydroxy group, their ring-closure reactions to 5 chroman derivatives, as well as the acylation of the latter and the aromatic compounds featuring at least one hydroxy group themselves. The present invention relates especially to a process for the manufacture of tocol, tocopherols and their alkanoates such as (x-tocopherol (TCP) and alkanoates (TCPA) thereof, preferably (x-toeopheryl acetate (TCPAc). The processes of the present invention are characterized in that at least one step of the processes is carried out in the presence of an indium salt as the catalyst.
    Type: Grant
    Filed: December 6, 2004
    Date of Patent: April 13, 2010
    Assignee: DSM IP Assets B.V. a Netherlands Corporation
    Inventors: Werner Bonrath, Yann Foricher, Thomas Netscher, Angela Wildermann
  • Patent number: 7695949
    Abstract: The present invention provides a process for producing a target fermentation product. This process includes providing a fermentation medium containing a recombinantly-produced microorganism that over-produces a fermentation product and contains a mutation which causes auxotrophic growth of the microorganism wherein the auxotrophy within the microorganism does not compromise the ability of the microorganism to produce the fermentation product. The medium is then supplied in excess with all substrates required for production of the fermentation product and in growth limiting amounts with a substrate complementing the auxotrophy. Host cells, vectors, and polynucleotide sequences used in the process are also provided. The polynucleotide sequences of the present invention include sequences derived from the biotin operon of B. subtilis and in particular the bioFDB gene cassette.
    Type: Grant
    Filed: October 8, 2003
    Date of Patent: April 13, 2010
    Assignee: DSM IP Assets B.V.
    Inventors: Hans-Peter Hohmann, Nigel John Mouncey, Heinrich Winfred Schlieker, Jeffrey W. Stebbins