Abstract: Compositions and methods for the treatment or prevention of Dengue virus infection in a vertebrate subject are provided. In particular, human neutralizing monoclonal antibodies to Dengue virus isolated from EBV immortalized B cells derived from patients who have recovered from Dengue infection are disclosed. Methods are provided for administering such antibodies to a vertebrate subject in an amount effective to reduce, eliminate, or prevent relapse from infection.

Abstract: A device for illuminating a target comprises a laser which produces a light beam, a viewing medium which receives electromagnetic radiation in an acceptance band, a beam-splitter which splits the light beam into a first beam and a second beam, and an imaging assembly. The imaging assembly comprises a light conversion medium and an element responsible for image creation comprising one of a light focusing medium and a light reflective medium. The first beam is directed along a travel path from the beam-splitter to the element and then to the light conversion medium, wherein the light conversion medium converts the first beam into electromagnetic radiation within the acceptance band. A spot object distance between the light conversion medium and the element is less than a target distance. The target distance is between the target and the beam-splitter less a distance between the beam-splitter and the element.

Abstract: Compositions and methods for the treatment or prevention of Dengue virus infection in a vertebrate subject are provided. In particular, human neutralizing monoclonal antibodies to Dengue virus isolated from EBV immortalized B cells derived from patients who have recovered from Dengue infection are disclosed. Methods are provided for administering such antibodies to a vertebrate subject in an amount effective to reduce, eliminate, or prevent relapse from infection.

Abstract: Various embodiments provide a method for landing an unmanned aerial vehicle (UAV) in the presence of a wind. The method comprises: performing a first flare-maneuver whilst the UAV is flying. The flare-maneuver causes a front portion of the UAV to rise with respect to a rear portion of the UAV. The method also comprises steering the UAV along a path heading into a direction of the wind. The method further comprises performing a second flare-maneuver before the UAV impacts a landing surface to land. Various embodiments provide a corresponding UAV.

Abstract: Described herein are antigen binding proteins that bind to pathogenic mycobacteria-derived Mannose-Capped Lipoarabinomannan (ManLAM) and methods and kits for using and making the antigen binding proteins. Also described herein are antigen binding proteins that bind to the alpha 1-2 linkage mannose caps of ManLAM, antigen binding proteins that bind to a mannose cap with up to three alpha 1-2 linked mannose residues, and antigen binding proteins that bind to LAM with a mannose sugar capping motif.

Abstract: A laser vibrometer makes non-contact measurements of vibrations of a target. A laser produces a laser beam, and a beamsplitter splits the laser beam into a reference beam and a first target beam. A first frequency shifter/splitter splits the first target beam into a pair of target beams each having a frequency different than a frequency of the other target beams. The target beams are reflected from the target to a detector, and the reference beam is combined with the target beams such that the detector receives the target beams and reference beam together.

Abstract: Described herein are antigen binding proteins that bind to pathogenic mycobacteria-derived Mannose-Capped Lipoarabinomannan (ManLAM) and methods and kits for using and making the antigen binding proteins. Also described herein are antigen binding proteins that bind to the alpha 1-2 linkage mannose caps of ManLAM, antigen binding proteins that bind to a mannose cap with up to three alpha 1-2 linked mannose residues, and antigen binding proteins that bind to LAM with a mannose sugar capping motif.

Abstract: An optical-limiter is disclosed herein. In an embodiment, the optical limiter comprises chemically functionalized graphene substantially spaced apart as single sheets in a substantially transparent liquid cell or solid thin film. A method of fabricating an optical response material is also disclosed.

Abstract: Compositions and methods for the treatment or prevention of Dengue virus infection in a vertebrate subject are provided. In particular, human neutralizing monoclonal antibodies to Dengue virus isolated from EBV immortalized B cells derived from patients who have recovered from Dengue infection are disclosed. Methods are provided for administering such antibodies to a vertebrate subject in an amount effective to reduce, eliminate, or prevent relapse from infection.

Abstract: A composition comprising a hydrogel particle and a fluorophore; wherein said composition produces an enhanced fluorescent signal when excited by an energy source capable of exciting the fluorophore.

Abstract: A laser vibrometer makes non-contact measurements of vibrations of a target. A laser produces a laser beam, and a beamsplitter splits the laser beam into a reference beam and a first target beam. A first frequency shifter/splitter splits the first target beam into a pair of target beams each having a frequency different than a frequency of the other target beams. The target beams are reflected from the target to a detector, and the reference beam is combined with the target beams such that the detector receives the target beams and reference beam together.

Abstract: A method of detecting an amount of a cholinesterase inhibitor in a sample comprising steps of: (a) contacting the sample with an agent capable of recovering the cholinesterase inhibitor from the sample so that the cholinesterase inhibitor is recovered, wherein the agent comprises a reactivity towards phosphyl moieties; (b) isolating the recovered cholinesterase inhibitor from the sample; (c) contacting the isolated cholinesterase inhibitor from step (b) with a test cholinesterase wherein the cholinesterase activity of the test cholinesterase before step (a) is known; and (d) measuring the cholinesterase activity to determine the amount of cholinesterase inhibitor in the sample based on the inhibition of the test cholinesterase activity from the known activity of the test cholinesterase before step (a).

Abstract: A device for illuminating a target comprises a laser which produces a light beam, a viewing medium which receives electromagnetic radiation in an acceptance band, a beam-splitter which splits the light beam into a first beam and a second beam, and an imaging assembly. The imaging assembly comprises a light conversion medium and an element responsible for image creation comprising one of a light focusing medium and a light reflective medium. The first beam is directed along a travel path from the beam-splitter to the element and then to the light conversion medium, wherein the light conversion medium converts the first beam into electromagnetic radiation within the acceptance band. A spot object distance between the light conversion medium and the element is less than a target distance. The target distance is between the target and the beam-splitter less a distance between the beam-splitter and the element.

Abstract: Passive antibody therapy as a tool for both prophylaxis against—and treatment of—highly pathogenic H5N1 influenza virus, providing immediate immunity is described. It is provided by an antibody specific to hemagglutinin capable of neutralizing influenza viruses and methods of making and using the same, the methods and compounds described herein may be used in diagnostic, prophylactic and therapeutic methods.

Abstract: A chemical dosimeter comprising: a chamber defined by a heat resistant mesh; and a quantity of an adsorbent contained within the chamber; the arrangement being such that gas may diffuse into the chamber through the heat resistant mesh so that chemicals in the gas may be adsorbed by the adsorbent.

Abstract: A device for producing laser radiation, the device comprising: an elongate sample of a quasi-three-level laser material; a source of pumping radiation; and a concentrator configured such that at least some of the pumping radiation emitted by the source of pumping radiation is concentrated by the concentrator and subsequently enters the sample through a side surface thereof.

Abstract: The invention provides a device for closing parachute packs, each of which has a plurality of flaps and a closing cord (36), the device (10) being characterised by a base (12) for bearing on a flap in one direction during the packing operation, and by a mechanism (18, 22) adapted to draw a pull cord (34) connectable to the closing cord (36) in substantially an opposite direction to allow the flaps to be secured relative to the closing cord (36) by a pin.

Abstract: A device for producing laser radiation having a wavelength of about 2 ?m, the device comprising: a solid-state sample capable of producing lasing transitions corresponding to a wavelength of about 2 ?m; and a source of pumping radiation having a wavelength of about 1 ?m, the source being arranged so that at least some of the radiation produced thereby is absorbed by the solid-state sample, causing the solid-state sample to emit radiation having a wavelength of about 2 ?m.

Abstract: An apparatus for generating laser radiation, the apparatus comprising: a pumping device comprising a resonant cavity; and a laser radiation generation element that is substantially Poynting vector walk-off compensated, the laser radiation generation element being located within the resonant cavity.

Abstract: A chemical dosimeter comprising: a chamber defined by a heat resistant mesh; and a quantity of an adsorbent contained within the chamber; the arrangement being such that gas may diffuse into the chamber through the heat resistant mesh so that chemicals in the gas may be adsorbed by the adsorbent.