Abstract: Interferon is produced in vivo or in vitro by administration of dipyridamole as interferon inducer to cellular material. Interferon may be induced in warm blooded animals by administration of dipyridamole orally in single doses of 1.0 to 100 mg/kg, intraperitoneally in single doses of 0.1 to 16.7 mg/kg and intravenously in an amount of 0.01 to 50 mg/kg.

Abstract: The invention comprises preparations for the treatment of neoplasms, the methods of treatment of neoplasms using such preparations, and processes for preparing such preparations, including the step of selective enzymatic degradation of the nuclei of cancer cells.The invention further comprises the method of treating patients suffering from neoplasms with immunomodulating agents obtained by isolating the genetically active components of cancer cell nuclei obtained from cancer tissue, subsequently recombining them by specific hybridization steps to prepare a vaccine therefrom, and intravenously, intraperitoneally and/or intramuscularly administering the resulting vaccine product to patients.

Abstract: Device for the production of temporary dental crowns having a die and a matrix. The die is an artificial tooth having a shape closely approximating that of the tooth being restored, a fixing and supporting shaft protruding from the middle of the artificial tooth. The matrix is cup-shaped with a recess into which an elastic ring is placed, the elastic ring pressing inwardly a plastic foil from which the temporary crown is formed about the die as it is thrust into the elastic ring. The relaxed internal diameter of the internal ring is smaller than the size of the lower part of the tooth being restored. Concentrically with the space in the open end of the matrix there is provided a socket with an outside flange within which the outer edge of the plastic foil is initially held. The device can produce temporary plastic dental crowns which closely approximate the shape of the tooth being restored, and it is easy to take the crown off the matrix and the die without any damage thereto.

Abstract: A vaccine effective against pertussis in infants, administered orally, comprises live bacteria of the Bordetella pertussis strain EM 1964.

Abstract: A biologically creative polyamide net which is non-allergenic, non-carcinogenic, non-toxic and compatible with the human body is obtained by treating a polyamide net knit in a sequence of washing operations and activating the net with a solution of a antibacterial composition at elevated temperatures.

Abstract: A process for preparing compounds of the formula: ##STR1## or pharmaceutically acceptable salts thereof, wherein R.sub.1 and R.sub.2 each individually are hydrogen, halogen, or nitro, which comprises the steps of: (a) alkylating a compound of the formula: ##STR2## wherein R.sub.3 is C.sub.1 to C.sub.4 alkyl or phenyl, with a compound of the formula:R.sub.4 --Xwherein R.sub.4 is C.sub.1 to C.sub.6 alkyl or phenyl-alkyl where the alkyl is C.sub.1 to C.sub.4 and X is halogen, in the presence of a base to yield a compound of the formula: ##STR3## and; (b) cyclizing the compound formed during step (a) with ethylenediamine mono-p-toluenesulphonate at a temperature of 100.degree. to 200.degree. C. to yield the desired product. New intermediate compounds are also disclosed. The desired products have antihypertensive properties.

Abstract: A novel cosmetic is obtained by mechanical mixing of a 0.6-0.8% solution of a collagen and adding thereto from 0.6-1% of pyridoxal phosphate.

Abstract: An antibiotic with high activity of the rifamycin class with the formula ##STR1## in which R is biphenylmethyl, cinnamyl or alpha-naphthylmethyl.

Abstract: An R,S-[2-(2-hydroxyethylamino)-1-phenyl]-ethylamine of the formula III ##STR1## wherein R represents hydrogen, allyl, propargyl or benzyl. These compounds provide valuable intermediates for the synthesis of Tetramisole.

Abstract: The invention covers the following compounds: 5-(N-benzoylthiocarbamoyl)-5H-dibenz [b, f] azepine, 5-thiocarbamoyl-5H-dibenz [b,f] azepine, 5-(S-methylisothiocarbamoyl)-5H-dibenz [b,f]-azepine and their 10,11-dihydro analogs. These compounds are intermediates for psychoactive drugs.

Abstract: A preparation is disclosed for treating gastritis and gastric and duodenal ulcers which comprises dried soya medium, sucrose, and dried Lactobacillus bulgaricus culture which has been obtained by cultivating the culture in a soya medium under anaerobic conditions at a temperature of between 35.degree.-42.degree. C, followed by spray drying the culture at a temperature of 150.degree.-190.degree. C. The culture consists of 25-35% protein, 45-52% sucrose, and 4-5.5% lactic acid.

Abstract: This invention provides method for obtaining tetracycline hydrochloride through interaction of a suspension consisting of tetracycline base in an organic solvent with concentrated hydrochloric acid, wherein the solution containing tetracycline base and hydrochloric acid is treated by high-frequency oscillations.

Abstract: Method of producing microcrystalline cellulose. Cellulose containing at least about 92% alpha-cellulose and 5 - 6.5% beta cellulose, having a solubility in 5% sodium hydroxide of about 2 to 4% and a viscosity 110 to 180 mP is acid hydrolyzed and the resulting crystalline mass is de-aggregated, the acid hydrolysis being performed at the same time as the chemical de-aggregating of the material. The de-aggregated material may be bleached and cleaned if desired.