Abstract: A novel dosing treatment for the administration of botulinum toxin injected into the calf muscle, namely, gastrocnemius-soleus complex in a range of about 50 to about 180 units and foot muscle group comprising one or more of a group consisting of the plantar intrinsic muscles, the plantar fascia muscles and calcaneal periosteum muscles in a range of about 20 to about 90 units of a patient to treat plantar fasciitis.
Abstract: A novel dosing regimen for the administration of botulinum toxin based on the pattern, quantity, and location of neuromuscular junctions in the target tissue. Because the number of neuromuscular junctions in a target tissue remains generally stable throughout life and because the pharmacological effect of botulinum toxin is localized at the neuromuscular junction, dosing efficacy is unaffected by muscle mass, age of the patient, or body weight.
Abstract: A novel dosing regimen for the administration of botulinum toxin based on the pattern, quantity, and location of neuromuscular junctions in the target tissue. Because the number of neuromuscular junctions in a target tissue remains generally stable throughout life and because the pharmacological effect of botulinum toxin is localized at the neuromuscular junction, dosing efficacy is unaffected by muscle mass, age of the patient, or body weight.
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