Patents Assigned to Duke Univerity
  • Hydrogels formed from polypeptide micelles and methods of use thereof
    Patent number: 9956300
    Abstract: The presently disclosed subject matter is directed to compositions, methods, and systems (e.g., platforms) comprising the same, the systems comprising, consisting of, or consisting essentially of micro- and macro-hydrogels that are formed from polypeptide micelles. The systems have enhanced mechanical properties that can be useful in a wide variety of applications, can be used for controlled release of drug-loaded micelles, and can be designed to reversibly assemble and disassemble on demand.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: May 1, 2018
    Assignee: Duke Univerity
    Inventors: Gabriel P. Lopez, Ashutosh Chilkoti, Ali Ghoorchian, Joseph R. Simon
  • Antiparkinsonian action of phenylisopropylamines
    Patent number: 8877802
    Abstract: A method of treating a subject for Parkinson's disease comprises administering said subject a phenylisopropylamine in an amount effective to treat said Parkinson's disease. In some embodiments the method is used to treat at least a motor symptom of Parkinson's disease; in some embodiments the method is used to treat at least a non-motor symptom of Parkinson's disease.
    Type: Grant
    Filed: July 26, 2006
    Date of Patent: November 4, 2014
    Assignee: Duke Univerity
    Inventors: Marc G. Caron, Tatyana D. Sotnikova, Raul R. Gainetdinov