Patents Assigned to Dupont Nutrition Biosciences APS
  • Patent number: 11931385
    Abstract: A feed additive composition comprising a direct fed microbial (DFM), in combination with a xylanase (e.g. endo-1,4-?-d-xylanase) and a ?-glucanase (and optionally a further fibre degrading enzyme).
    Type: Grant
    Filed: July 6, 2021
    Date of Patent: March 19, 2024
    Assignee: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Mai Faurschou Isaksen, Marion Bernardeau, Luis Fernando Romero Millan, Elijah G. Kiarie, Susan Lund Arent, Päivi Nurminen, Sofia Forssten, Daniel Petri, Elizabeth Ann Galbraith, Mari Ellen Davis
  • Patent number: 11883446
    Abstract: This invention relates to bacterial strains, compositions comprising bacterial strains as well as methods and uses of said strains and compositions for preventing or treating illness and/or symptoms associated with a coronavirus in a subject in need thereof.
    Type: Grant
    Filed: April 1, 2022
    Date of Patent: January 30, 2024
    Assignee: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Sebastien Guery, Markus Lehtinen, Sinikka Anneli Latvala, Liisa Lehtoranta, Bryan-James Zabel, Wesley William Morovic, Charles Budinoff, Scott D. Power
  • Patent number: 11884942
    Abstract: An isolated and/or purified ?-glucanotransferase from Exiguobacterium acetylicum, recombinantly engineered variants thereof, active fragments thereof, synthetic nucleic acids encoding the ?-glucanotransferase and variants thereof, host cells comprising the synthetic nucleic acids, and compositions comprising the ?-glucanotransferase are provided. Methods of using the compositions include the manufacture of oligosaccharides.
    Type: Grant
    Filed: July 22, 2021
    Date of Patent: January 30, 2024
    Assignee: DUPONT NUTRITION BIOSCIENCES APS
    Inventor: Slavko Kralj
  • Patent number: 11844356
    Abstract: The present invention relates to a method of making a dough, said method comprises admixing a dough component, a phospholipase A2 enzyme which acts on N-acyl phosphatidyl ethanolamine at the sn2 position, and an enzyme that acts on a polar lipid at the sn1 position. A food enzyme composition comprising: a phospholipase A2 enzyme which is capable of acting on N-acylphosphatidyl ethanolamine at the sn2 position; and an enzyme that acts on a polar lipid at the sn1 position is also taught.
    Type: Grant
    Filed: April 28, 2021
    Date of Patent: December 19, 2023
    Assignee: DuPont Nutrition Biosciences APS
    Inventors: Jorn Borch Soe, Rene Mikkelsen, Tina Lillan Joergensen
  • Patent number: 11744254
    Abstract: A phospholipase A1 characterized by having an sn1/sn2 specificity ratio of about 55/45 or greater wherein said phospholipase A1 has a lysophospholipase/phospholipase activity ratio of less than 0.02 is presented in conjunction with methods for use in lipid containing food matrix, baking and making dough with the phospholipase and also including baking improvers using the disclosed phospholipase A1.
    Type: Grant
    Filed: December 17, 2018
    Date of Patent: September 5, 2023
    Assignee: DuPont Nutrition Biosciences APS
    Inventors: Keya Zhang, Lone Broend Miller, Lene Kragh, Tina Lillan Joergensen
  • Patent number: 11732251
    Abstract: Methods and compositions are provided for the use of anti-CRISPR (ACR) proteins in plants, including modulation of Cas endonuclease activity, improvement of frequency of homologous recombination, control of Cas endonuclease activity during various cell cycles, spatial and/or temporal regulation of Cas endonuclease activity in plants, usage in gene activation or repression, as well as reduction of off-target polynucleotide cleavage.
    Type: Grant
    Filed: April 24, 2018
    Date of Patent: August 22, 2023
    Assignees: DUPONT NUTRITION BIOSCIENCES APS, UNIVERSITE LAVAL (CANADA)
    Inventors: Christophe Fremaux, Philippe Horvath, Alexander Hynes, Marie-Laurence Lemay, Sylvain Moineau, Dennis A. Romero, Geneviève Rousseau, Joshua K Young
  • Patent number: 11725199
    Abstract: The invention is directed to a lactose-positive, galactose-negative, Streptococcus thermophilus strain releasing glucose during milk fermentation. This Streptococcus thermophilus strain carries mutation in the glcK gene, in the ccpA gene, in the lacZ gene and/or in the ptsH gene, and optionally in one or more genes, in particular one gene, encoding a protein of the mannose-glucose-specific PTS. The invention also concerns a composition comprising at least one, lactose-positive, galactose-negative, Streptococcus thermophilus strain of the invention, and the use of this strain or composition to manufacture a fermented dairy product.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: August 15, 2023
    Assignee: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Armelle Cochu-Blachere, Christophe Fremaux, Thomas Desfougeres
  • Patent number: 11634673
    Abstract: The present disclosure provides methods, compositions, apparatuses and kits comprising two or more distant related glucoamylases in mashing having a synergistic effect on the released fermentable DPI sugar. Increased levels of DPI being primarily glucose is of high importance for high attenuation brewing applied for brewing low carb or light beers. In some embodiments, the present disclosure provides methods, apparatuses; compositions and kits for the use of two or more glucoamylases to increase the apparent specific activity in the mashing operation.
    Type: Grant
    Filed: September 19, 2018
    Date of Patent: April 25, 2023
    Assignee: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Jacob Flyvholm Cramer, Tove Bladt
  • Patent number: 11578316
    Abstract: Compositions and methods are provided comprising acetolactate decarboxylase (ALDC) enzyme variants having higher specific activity. Composition and method are provided where the ALDC variants are used in combination with metal ions to further increase stability and/or activity.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: February 14, 2023
    Assignee: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Jacob Flyvholm Cramer, Lene Kragh
  • Patent number: 11530405
    Abstract: The invention relates to anti-CRISPR genes and anti-CRISPR proteins, and their uses in various biotechnology applications.
    Type: Grant
    Filed: April 24, 2018
    Date of Patent: December 20, 2022
    Assignees: DUPONT NUTRITION BIOSCIENCES APS, UNIVERSITE LAVAL (CANADA)
    Inventors: Christophe Fremaux, Philippe Horvath, Dennis A. Romero, Sylvain Moineau, Alexander Hynes, Geneviève Rousseau
  • Patent number: 11479763
    Abstract: Certain embodiments of the disclosure are directed to the expression/production of ?-galactosidases in recombinant Bacillus spp. host cells having reduced or eliminated para-nitrobenzylesterase activity.
    Type: Grant
    Filed: April 5, 2018
    Date of Patent: October 25, 2022
    Assignee: Dupont Nutrition Biosciences APS
    Inventors: Cristina Bongiorni, Karina Hansen Kjaer
  • Patent number: 11470864
    Abstract: The present invention relates to a culture or kit-of-part comprising a Lactobacillus delbrueckii subsp lactis strain, and uses thereof to manufacture a cereal-based lactic acid-fermented product, in particular a maize-based lactic acid-fermented product such as mahewu.
    Type: Grant
    Filed: April 12, 2017
    Date of Patent: October 18, 2022
    Assignee: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Pascal Fourcassie, Claire Bonard, Veronique Laffitte, Brett Wordon
  • Patent number: 11473073
    Abstract: The present disclosure provides polypeptides having aminopeptidase activity and isolated nucleic acid sequences encoding the polypeptides. In some embodiments, the disclosure also provides to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing the polypeptides. In some embodiments, the present disclosure further provides to methods of obtaining protein hydrolysates useful as flavor improving agents.
    Type: Grant
    Filed: June 27, 2016
    Date of Patent: October 18, 2022
    Assignee: Dupont Nutrition Biosciences APS
    Inventors: Karsten Matthias Kragh, Ernst Meinjohanns, Thomas Eisele, Peter Edvard Degn, Steffen Yde Bak
  • Patent number: 11382938
    Abstract: A method for Inhibiting or Delaying the Growth of Enterococcus spp. in Animals using at least one Bacillus-based component is disclosed herein.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: July 12, 2022
    Assignee: DuPont Nutrition Biosciences APS
    Inventors: Marion Bernardeau, Alexandra Wealleans
  • Publication number: 20220174981
    Abstract: A method for the production of a hydrolysate comprising: (a) admixing at least one protein or a portion thereof with: (A) at least one endoprotease; and (B) (a?) at least one proline tolerant tripeptidyl peptidase or fermentate comprising a proline tolerant tripeptidyl peptidase predominantly having exopeptidase activity wherein said proline tolerant tripeptidyl peptidase is capable of cleaving tri-peptides from the N-terminus of peptides having: Proline at P1; and synthetic amino acids at P1; or (b?) at least one proline tolerant tripeptidyl peptidase having exopeptidase activity wherein said proline tolerant tripeptidyl peptidase is capable of cleaving tri-peptides from the N-terminus of peptides having: Proline at PV; and synthetic amino acids at PV; and (b) recovering the hydrolysate.
    Type: Application
    Filed: November 24, 2021
    Publication date: June 9, 2022
    Applicant: DuPont Nutrition Biosciences APS
    Inventors: Karsten Matthias KRAGH, Ernst MEINJOHANNS, Andrei MIASNIKOV, Maria MA, Thomas EISELE, Svend HAANING, Peter Edvard DEGN, Steffen Yde BAK
  • Publication number: 20220169974
    Abstract: The invention relates to a polynucleotide comprising a lacZ gene (lacZFS) encoding a ?-galactosidase characterized by a particular profile regarding its efficiency of hydrolysis of lactose. The invention is also directed to a Streptococcus thermophilus strain comprising a lacZFS allele and bacterial composition thereof, and their use to obtain fermented milk not undergoing post-acidification.
    Type: Application
    Filed: March 13, 2020
    Publication date: June 2, 2022
    Applicant: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Anais JEDRZEJOWSKI, Christophe FREMAUX, Sabine VAN DILLEN, Thomas DESFOUGERES, Max Charles JODEAU, Damien LUGAND
  • Publication number: 20220159981
    Abstract: The present invention relates to polypeptides, specifically polypeptides having transgalactosylating activity and nucleic acids encoding these, and their uses in e.g. dairy product.
    Type: Application
    Filed: September 7, 2021
    Publication date: May 26, 2022
    Applicant: DuPont Nutrition Biosciences ApS
    Inventors: MORTEN KROG LARSEN, Jacob FLYVHOLM CRAMER
  • Publication number: 20220117247
    Abstract: The present invention relates to a lactic acid bacterium, in particular a strain of the Streptococcus genus, with reduced sensitivity to cos-type bacteriophages. The invention also relates to methods to engineer these lactic acid bacteria as well as their use to ferment milk.
    Type: Application
    Filed: February 13, 2020
    Publication date: April 21, 2022
    Applicant: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Christophe FREMAUX, Philippe HORVATH, Armelle COCHU-BLACHÈRE, Dennis ROMERO, Sylvain MOINEAU, Simon LABRIE
  • Publication number: 20220040241
    Abstract: A feed additive composition comprising a direct fed microbial (DFM), in combination with a xylanase (e.g. endo-1,4-?-d-xylanase) and a ?-glucanase (and optionally a further fibre degrading enzyme).
    Type: Application
    Filed: July 6, 2021
    Publication date: February 10, 2022
    Applicant: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Mai Faurschou Isaksen, Marion Bernardeau, Luis Fernando Romero Millan, Elijah G. Kiarie, Susan Arent Lund, Päivi Nurminen, Sofia Forssten, Daniel Petri, Elizabeth Ann Galbraith, Mari Ellen Davis
  • Publication number: 20210360937
    Abstract: The present invention relates to the solubilisation of cereal bran, for preparing compositions comprising soluble fractions of cereal bran and the use of these compositions comprising solubilised cereal bran for the preparation of food products, such as bread.
    Type: Application
    Filed: June 3, 2021
    Publication date: November 25, 2021
    Applicant: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: JENS FRISBAEK SØRENSEN, RENE MIKKELSEN, CHARLOTTE HORSMANS POULSEN, KARSTEN MATTHIAS KRAGH